Associations between Serum Levels of #Cholesterol and #survival to Age 90 in Postmenopausal Women

Although elevated lipid levels predict increased risk of coronary heart disease and death in middle‐aged women and men, evidence is mixed if lipid levels measured in later life predict survival to very old ages..

HDL and LDL levels were not associated with survival to age 90 after adjustment for cardiovascular risk factors..

Similarly, no associations were observed between HDL and LDL levels and survival to age 90 with mobility disability. High HDL was not associated with survival to age 90 with intact mobility after adjustment for other cardiovascular risk factors. Compared with the lowest LDL quartile, the three upper LDL quartiles were associated with greater odds of survival to age 90 with intact mobility..

Neither higher HDL nor lower LDL levels predicted survival to age 90, but higher LDL predicted healthy survival. These findings suggest the need for reevaluation of healthy LDL levels in older women.