Association of #sugary drink consumption with all-cause and cause-specific #mortality: the Japan Public Health Center-based Prospective Study

Highlights•We assessed the association between sugary drinks and mortality in Japan. •Sugary drink consumption was positively associated with all-cause mortality. •Sugary drinks increased risk of death from circulatory system diseases. AbstractBackgroundFew epidemiologic studies have assessed the associations of sugary drink consumption with mortality outcomes among Asian populations. MethodsThis study included 70,486 participants in the Japan Public Health Center-based Prospective Study at the age of 45–74 … Continue reading Association of #sugary drink consumption with all-cause and cause-specific #mortality: the Japan Public Health Center-based Prospective Study

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Association of Major Dietary #Protein Sources With All‐Cause and Cause‐Specific #Mortality: Prospective Cohort Study

Dietary recommendations regarding protein intake have been focused on the amount of protein. However, such recommendations without considering specific protein sources may be simplistic and insufficient. Methods and Results We included 102 521 postmenopausal women enrolled in the Women’s Health Initiative between 1993 and 1998, and followed them through February 2017. During 1 876 205 person‐years of follow‐up, 25 976 deaths occurred. Comparing the highest … Continue reading Association of Major Dietary #Protein Sources With All‐Cause and Cause‐Specific #Mortality: Prospective Cohort Study

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#Personality pathways to mortality: Interleukin-6 links conscientiousness to #mortality risk

Personality is associated consistently with mortality hazards, but the physiological pathways are not yet clear. Immune system dysregulation may be one such pathway due to its role in age-related morbidity and mortality. In this preregistered study, we tested whether interleukin-6 (IL-6) and C-reactive protein (CRP) mediated the associations between personality traits and mortality hazards. The sample included 957 participants (M ± SD = 58.65 ± … Continue reading #Personality pathways to mortality: Interleukin-6 links conscientiousness to #mortality risk

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Risk of #Cardiovascular Disease Mortality in Relation to #Depression and 14 Common Risk Factors

Depression has been linked to a worse prognosis of Cardiovascular disease (CVD), and these two diseases share a variety of common risk factors such as unhealthy lifestyles and chronic medical conditions. However, the potential role of these common risk factors in modulating the association between depression and CVD mortality and whether the co-occurrence of depression and a specific common risk factor has a cumulative impact … Continue reading Risk of #Cardiovascular Disease Mortality in Relation to #Depression and 14 Common Risk Factors

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Association of Medical #Stimulants With #Mortality in the US From 2010 to 2017

The role of nonopioids in the drug overdose epidemic in the US is frequently overshadowed. From 2015 to 2016, mortality rates involving cocaine and psychostimulants were smaller than opioids, but were rising faster than opioids.1 We examined individual substances listed on death certificates to better understand stimulant-associated mortality and assess rates over time. https://bit.ly/3oEgFbP Continue reading Association of Medical #Stimulants With #Mortality in the US From 2010 to 2017

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Clinical Outcomes in Patients With Heart #Failure Hospitalized With #COVID-19

The purpose of this study was to evaluate in-hospital outcomes among patients with a history of heart failure (HF) hospitalized with coronavirus disease-2019 (COVID-19).. ..Among 1,212,153 patients with history of HF, 132,312 patients were hospitalized from April 1, 2020, to September 30, 2020. A total of 23,843 patients (18.0%) were hospitalized with acute HF, 8,383 patients (6.4%) were hospitalized with COVID-19, and 100,068 patients (75.6%) … Continue reading Clinical Outcomes in Patients With Heart #Failure Hospitalized With #COVID-19

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#Glucosamine #Chondroitin and Mortality in a US NHANES Cohort

Background: Limited previous studies in the United Kingdom or a single US state have demonstrated an association between intake of glucosamine/chondroitin and mortality. This study sought to investigate the association between regular consumption of glucosamine/chondroitin and overall and cardiovascular (CVD) mortality in a national sample of US adults. Methods: Combined data from 16,686 participants in National Health and Nutrition Examination Survey 1999 to 2010, merged … Continue reading #Glucosamine #Chondroitin and Mortality in a US NHANES Cohort

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Prognostic value of #electrocardiographic abnormalities in adults from the Brazilian longitudinal study of adults’ health

Cardiovascular diseases (CVDs) are highly preventable non-communicable diseases. ECG is a potential tool for risk stratification with respect to CVD. Our aim was to evaluate ECG’s role in all-cause and cardiovascular mortality prediction. Methods Participants from the Brazilian Longitudinal Study of Adult Health, free of known CVD at baseline were included. A 12-lead ECG was obtained at baseline (2008–2010). Participants were followed up to 2018 … Continue reading Prognostic value of #electrocardiographic abnormalities in adults from the Brazilian longitudinal study of adults’ health

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Evaluation of Time to Benefit of #Statins for the Primary Prevention of Cardiovascular Events in Adults Aged 50 to 75 Years A Meta-analysis

Guidelines recommend targeting preventive interventions toward older adults whose life expectancy is greater than the intervention’s time to benefit (TTB). The TTB for statin therapy is unknown To conduct a survival meta-analysis of randomized clinical trials of statins to determine the TTB for prevention of a first major adverse cardiovascular event (MACE) in adults aged 50 to 75 years.. Eight trials randomizing 65 383 adults (66.3% … Continue reading Evaluation of Time to Benefit of #Statins for the Primary Prevention of Cardiovascular Events in Adults Aged 50 to 75 Years A Meta-analysis

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#Dementia and the risk of death in elderly patients with #COVID‐19 infection: Systematic review and meta‐analysis

The COVID‐19 infection represents a global public health emergency worldwide. Several risk factors have been associated with a poor prognosis among COVID‐19 patients. We aimed to perform a systemic review and meta‐analysis to evaluate the mortality risk in elderly patients with dementia and COVID‐19 infection.. ..A total of 233 articles were retrieved; 158 were excluded for not meeting the inclusion criteria, leaving 75 articles to … Continue reading #Dementia and the risk of death in elderly patients with #COVID‐19 infection: Systematic review and meta‐analysis

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Mortality risk of #antipsychotic augmentation for adult depression

Randomized controlled trials have demonstrated increased all-cause mortality in elderly patients with dementia treated with newer antipsychotics. It is unknown whether this risk generalizes to non-elderly adults using newer antipsychotics as augmentation treatment for depression.. ..Non-elderly adults (25–64 years) diagnosed with depression who after ≥3 months of antidepressant monotherapy initiated either augmentation with a newer antipsychotic or with a second antidepressant. Patients with alternative indications … Continue reading Mortality risk of #antipsychotic augmentation for adult depression

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Low High‐Sensitivity C‐ #Reactive Protein Level in Korean Patients With Chronic #Kidney Disease and Its Predictive Significance for Cardiovascular Events, Mortality, and Adverse Kidney Outcomes: Results From KNOW‐CKD

Inflammation levels are lower in East Asians than in Western people. We studied the association between high‐sensitivity hs‐CRP (C‐reactive protein) and adverse outcomes in Korean patients with chronic kidney disease. Methods and Results We included 2018 participants from the KNOW‐CKD (Korean Cohort Study for Outcome in Patients With Chronic Kidney Disease) between April 2011 and February 2016. The primary outcome was a composite of extended … Continue reading Low High‐Sensitivity C‐ #Reactive Protein Level in Korean Patients With Chronic #Kidney Disease and Its Predictive Significance for Cardiovascular Events, Mortality, and Adverse Kidney Outcomes: Results From KNOW‐CKD

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