Tag: mortality

Environment, Sports

Association of Daily #Step Count and Step Intensity With Mortality Among US Adults

..Accelerometer-measured number of steps per day and 3 step intensity measures (extended bout cadence, peak 30-minute cadence, and peak 1-minute cadence [steps/min]). Accelerometer data were based on measurements obtained during a 7-day period at baseline. .. A total of 4840 participants (mean age, 56.8 years; 2435 [54%] women; 1732 [36%] individuals with obesity) wore accelerometers for a mean of 5.7 days for a mean of … Continue reading Association of Daily #Step Count and Step Intensity With Mortality Among US Adults

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Infectivology

Clinical course and risk factors for mortality of adult inpatients with #COVID-19 in Wuhan, China: a retrospective cohort study

Since December, 2019, Wuhan, China, has experienced an outbreak of coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Epidemiological and clinical characteristics of patients with COVID-19 have been reported but risk factors for mortality and a detailed clinical course of illness, including viral shedding, have not been well described.. ..91 (48%) patients had a comorbidity, with hypertension being the … Continue reading Clinical course and risk factors for mortality of adult inpatients with #COVID-19 in Wuhan, China: a retrospective cohort study

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Cardiology, Gerontology, Hypertension, Uncategorized

Blood #pressure in frail older adults: associations with #cardiovascular outcomes and all-cause mortality

Blood pressure (BP) management in frail older people is challenging. An randomised controlled trial of largely non-frail older people found cardiovascular and mortality benefit with systolic (S) BP target <120 mmHg. However, all-cause mortality by attained BP in routine care in frail adults aged above 75 is unclear.. ..Risks of cardiovascular outcomes increased with SBPs >150 mmHg. Associations with mortality varied between non-frail <85 and … Continue reading Blood #pressure in frail older adults: associations with #cardiovascular outcomes and all-cause mortality

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Cardiology

Clinical Implications of the New York Heart Association Classification

The New York Heart Association (NYHA) classification has served as a fundamental tool for risk stratification of heart failure (HF) and determines clinical trial eligibility and candidacy for drugs and devices. However, its ability to adequately stratify risk is unclear.. Cumulative mortality varied significantly across NYHA classes and HF clinical trials (likelihood ratio, P<0.001). Mortality at 20 months for NYHA class II ranged from 7% … Continue reading Clinical Implications of the New York Heart Association Classification

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Environment

#Education, Race/Ethnicity, and Causes of Premature #Mortality Among Middle-Aged Adults in 4 US Urban Communities: Results From CARDIA, 1985–2017

..Our primary outcome was years of potential life lost (YPLL). Results. The age-adjusted mortality rate per 1000 persons was 45.17 among Black men, 25.20 among White men, 17.63 among Black women, and 10.10 among White women. Homicide and AIDS were associated with the most YPLL, but cancer and cardiovascular disease were the most common causes of death. In multivariable models, each level of education achieved … Continue reading #Education, Race/Ethnicity, and Causes of Premature #Mortality Among Middle-Aged Adults in 4 US Urban Communities: Results From CARDIA, 1985–2017

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Diet

Association of Low-Carbohydrate and Low-Fat #Diets With #Mortality Among US Adults

..Overall low-carbohydrate-diet and low-fat-diet scores were not associated with total mortality. The multivariable-adjusted hazard ratios for total mortality per 20-percentile increase in dietary scores were 1.07 (95% CI, 1.02-1.11; P = .01 for trend) for unhealthy low-carbohydrate-diet score, 0.91 (95% CI, 0.87-0.95; P < .001 for trend) for healthy low-carbohydrate-diet score, 1.06 (95% CI, 1.01-1.12; P = .04 for trend) for unhealthy low-fat-diet score, and 0.89 (95% CI, 0.85-0.93; P < .001 for … Continue reading Association of Low-Carbohydrate and Low-Fat #Diets With #Mortality Among US Adults

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Diet, Oncology

Prevalence and clinical implications of #sarcopenic obesity in patients with solid tumours of the respiratory and gastrointestinal tracts: a population-based study

Emerging evidence on body composition suggests that sarcopenic obesity (obesity with depleted muscle mass) might be predictive of morbidity and mortality in non-malignant disease and also of toxicity to chemotherapy.. ..Available lumbar CT images of the obese patients were analysed for total skeletal muscle cross-sectional area; these values were also used to estimate total body fat-free mass (FFM).. ..Sarcopenic obesity was associated with poorer functional … Continue reading Prevalence and clinical implications of #sarcopenic obesity in patients with solid tumours of the respiratory and gastrointestinal tracts: a population-based study

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Infectivology

Predictors of #mortality of #influenza virus infections in a Swiss Hospital during four influenza seasons: Role of quick sequential organ failure assessment

..Thirty-day mortality was 6.0% (25 patients). Multivariate analysis revealed that infection due to A virus (P 0.035; OR 7.1; 95% CI 1.1–43.8), malnutrition (P < 0.001; OR 25.0; 95% CI 4.5–138.8), hospital-acquired infection (P 0.003; OR 12.2; 95% CI 2.3–65.1), respiratory insufficiency (PaO2/FiO2 < 300) (P < 0.001; OR 125.8; 95% CI 9.6–1648.7) and pulmonary infiltrate on X-ray (P 0.020; OR 6.0; 95% CI 1.3–27.0) … Continue reading Predictors of #mortality of #influenza virus infections in a Swiss Hospital during four influenza seasons: Role of quick sequential organ failure assessment

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Gerontology, Pneumology

Characteristics of Patients Experiencing Rehospitalization or Death After Hospital Discharge in a Nationwide Outbreak of #E-cigarette, or #Vaping, Product Use–Associated Lung Injury — United States, 2019

Some patients hospitalized for e-cigarette, or vaping, product use–associated lung injury (EVALI) have been rehospitalized or have died after hospital discharge.. ..Compared with other EVALI patients, rehospitalized patients and patients who died after hospital discharge were more likely to have one or more chronic conditions, including cardiac disease, chronic pulmonary disease, and diabetes, and to be older. At least one quarter of rehospitalizations and deaths … Continue reading Characteristics of Patients Experiencing Rehospitalization or Death After Hospital Discharge in a Nationwide Outbreak of #E-cigarette, or #Vaping, Product Use–Associated Lung Injury — United States, 2019

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Environment

Association Between #Automotive Assembly Plant Closures and #Opioid Overdose Mortality in the United States

..Automotive assembly plant closures are culturally significant events that substantially erode local economic opportunities. ..Automotive assembly plant closures were associated with statistically significant increases in opioid overdose mortality. Five years after a plant closure, mortality rates had increased by 8.6 opioid overdose deaths per 100 000 individuals (95% CI, 2.6-14.6; P = .006) in exposed counties compared with unexposed counties, an 85% increase relative to the mortality rate … Continue reading Association Between #Automotive Assembly Plant Closures and #Opioid Overdose Mortality in the United States

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Gerontology, Sports

Association of #Step Volume and Intensity With All-Cause #Mortality in Older Women

A goal of 10 000 steps/d is commonly believed by the public to be necessary for health, but this number has limited scientific basis.. ..In spline analysis, HRs were observed to decline progressively with higher mean steps per day until approximately 7500 steps/d, after which they leveled. For measures of stepping intensity, higher intensities were associated with significantly lower mortality rates; however, after adjusting for steps … Continue reading Association of #Step Volume and Intensity With All-Cause #Mortality in Older Women

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Cardiology, Environment

Birth #month, birth season, and overall and cardiovascular disease #mortality in US women: prospective cohort study

..In fully adjusted multivariable analyses, no significant association was observed between birth month, birth season, and overall mortality. Compared with women born in November, increased cardiovascular disease mortality was observed among those born from March to July (hazard ratio for March, 1.09, 95% confidence interval 0.98 to 1.21; April, 1.12, 1.00 to 1.24; May, 1.08, 0.98 to 1.20; June, 1.07, 0.96 to 1.19; and July … Continue reading Birth #month, birth season, and overall and cardiovascular disease #mortality in US women: prospective cohort study

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