Rising temperatures erode human sleep globally

Insufficient sleep is a risk factor for several adverse physical and mental outcomes. A lack of sleep has been associated with reduced cognitive performance, diminished productivity, compromised immune function, adverse cardiovascular outcomes, depression, anger, and suicidal behavior. High ambient temperatures have been associated with reduced subjective sleep quality, but little is known regarding the influence …

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Poor sleep may undermine people’s attempts to keep weight off

New research being presented at this year’s European Congress on Obesity (ECO) in Maastricht, Netherlands (4-7 May), finds that not getting enough good quality sleep undermines people’s attempts to keep weight off after dieting, and suggests that around two hours of vigorous physical activity per week can help maintain better sleep. The study is by …

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Sleep deprivation induces corneal epithelial progenitor cell over-expansion through disruption of redox homeostasis in the tear film

Sleep deficiency, a common public health problem, causes ocular discomfort and affects ocular surface health. However, the underlying mechanism remains unclear. Herein, we identified that short-term sleep deprivation (SD) resulted in hyperproliferation of corneal epithelial progenitor cells (CEPCs) in mice. The expression levels of p63 and Keratin 14, the biomarkers of CEPCs, were upregulated in …

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Subcortical Neuronal Correlates of Sleep in Neurodegenerative Diseases

Importance Sleep disturbance is common among patients with neurodegenerative diseases. Examining the subcortical neuronal correlates of sleep disturbances is important to understanding the early-stage sleep neurodegenerative phenomena. Objectives To examine the correlation between the number of important subcortical wake-promoting neurons and clinical sleep phenotypes in patients with Alzheimer disease (AD) or progressive supranuclear palsy (PSP). …

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Light exposure during sleep impairs cardiometabolic function

SignificanceAmbient nighttime light exposure is implicated as a risk factor for adverse health outcomes, including cardiometabolic disease. However, the effects of nighttime light exposure during sleep on cardiometabolic outcomes and the related mechanisms are unclear. This laboratory study shows that, in healthy adults, one night of moderate (100 lx) light exposure during sleep increases nighttime …

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