Buongiorno! My name is Aldo and I am an Internal Medicine Doctor. This is my Medical News Blog and I'm sure you'll find it useful and informative. All the articles can be searched by Category, Tag or Text. Just click on a post or on the Search link above.
Comparison of verbal autopsy using a large #language model to biologically confirmed causes of death for #malaria and other communicable diseases among children in six sub-Saharan African countries
Malaria, a preventable parasitic disease, causes most child deaths in sub-Saharan Africa (SSA). Reliable cause-of-death data are essential to evaluate progress toward the national and global malaria control goals. However, civil registration and vital statistics are often weak and incomplete in many low- and middle-income countries. In such circumstances, verbal autopsy (VA) provides an alternative… Continue reading Comparison of verbal autopsy using a large #language model to biologically confirmed causes of death for #malaria and other communicable diseases among children in six sub-Saharan African countries
Multimodality imaging in #hypertrophic #cardiomyopathy
Hypertrophic cardiomyopathy (HCM) is a myocardial disorder characterized by unexplained myocardial hypertrophy. Although the diagnosis of HCM is traditionally based on increased left ventricular (LV) wall thickness, contemporary management requires a comprehensive multimodality imaging approach to accurately define disease phenotype, assess functional consequences, and guide risk stratification. Transthoracic echocardiography remains the first-line imaging modality, providing… Continue reading Multimodality imaging in #hypertrophic #cardiomyopathy
The effect of post-operative continuous negative pressure therapy after debridement, antibiotics, and implant retention for acute #periprosthetic joint infection
Background: Acute periprosthetic joint infection (#PJI ) is a serious complication after total knee and hip replacement, with varying success rates in its management using debridement, antibiotics, and implant retention (DAIR). We hypothesize that the application of post-operative continuous negative pressure therapy (CNPT) can improve the success rate of DAIR in the treatment of acute… Continue reading The effect of post-operative continuous negative pressure therapy after debridement, antibiotics, and implant retention for acute #periprosthetic joint infection
Severe #copper deficiency–related polyneuropathy following laparoscopic sleeve #gastrectomy: A case report and literature review
Highlights•Timely copper repletion may yield favorable outcomes in severe copper deficiency–related polyneuropathy.•Review of prior SG and RYGB cases of copper deficiency–related polyneuropathy and their treatments and outcomes.•Neurological complication rates following SG and RYGB reported since 1976.•Reported incidence of copper deficiency between 6 and 24 mo after SG and RYGB.•Recommended laboratory tests for neurological complications following… Continue reading Severe #copper deficiency–related polyneuropathy following laparoscopic sleeve #gastrectomy: A case report and literature review
Clinical efficacy study on the efficacy and safety of #acupuncture for post- #stroke #dysphagia based on the regulation of the swallowing neural circuit: protocol for a multicenter, open-label, randomized controlled trial
Introduction: Post-stroke dysphagia (PSD) is a common complication of stroke. Rehabilitation training and acupuncture have been suggested as current effective therapies, but high-quality evidence of acupuncture is insufficient. A meta-analysis has shown that acupuncture may be an effective adjunctive treatment for improving swallowing function, but the guidelines do not provide sufficient recommendations. Therefore, clinical and… Continue reading Clinical efficacy study on the efficacy and safety of #acupuncture for post- #stroke #dysphagia based on the regulation of the swallowing neural circuit: protocol for a multicenter, open-label, randomized controlled trial
Effect of core stabilization exercises on #lumbar multifidus morphology and functional outcomes in chronic non-specific low #back pain: a randomized controlled trial
Background: Chronic non-specific low back pain (CNSLBP) is often associated with morphological changes in the lumbar multifidus muscle (LMF), such as reduced cross-sectional area (CSA) and increased fat infiltration, compromising spinal stability and function. Core stabilization exercises aim to enhance neuromuscular control by targeting deep trunk muscles. However, few randomized trials have investigated their effects… Continue reading Effect of core stabilization exercises on #lumbar multifidus morphology and functional outcomes in chronic non-specific low #back pain: a randomized controlled trial
#Electroacupuncture ameliorates skeletal muscle #insulin resistance in #diabetic rats via PPAR-γ/NF-κB signaling pathway
Objectives: To observe the effect of electroacupuncture (EA) at "Sanyinjiao" (SP6) and "Zusanli" (ST36) on the expressions of peroxisome proliferator-activated γ receptor (PPAR-γ), nuclear factor-κB (NF-κB) and glucose transporter 4 (GLUT4) in skeletal muscle of Zucker Diabetic Fatty (ZDF) rats with type 2 diabetes mellitus (T2DM), so as to explore its possible mechanism in improving… Continue reading #Electroacupuncture ameliorates skeletal muscle #insulin resistance in #diabetic rats via PPAR-γ/NF-κB signaling pathway
Effect of #acupuncture intervention combined with lateral approach #sciatic nerve block on postoperative analgesia in patients after total #knee #arthroplasty
Objectives: To explore the effect of acupuncture intervention combined with lateral approach sciatic nerve block (LSNB) on postoperative analgesia in patients after total knee arthroplasty (TKA).Methods: A total of 90 patients scheduled for TKA between May 2022 and May 2024 were selected as the study subjects. They were randomly divided into a control group and… Continue reading Effect of #acupuncture intervention combined with lateral approach #sciatic nerve block on postoperative analgesia in patients after total #knee #arthroplasty
Effects of glucagon-like peptide-1 on systemic hemodynamics, kidney function, and intrarenal oxygenation in sheep with sepsis-associated acute kidney injury
Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) reduce chronic kidney disease progression in people with type 2 diabetes mellitus. Sepsis is the leading cause of acute kidney injury (AKI). This study investigated whether GLP-1 is renoprotective in an ovine model of gram-negative septic AKI. Sixteen healthy merino ewes were surgically instrumented to measure mean arterial pressure,… Continue reading Effects of glucagon-like peptide-1 on systemic hemodynamics, kidney function, and intrarenal oxygenation in sheep with sepsis-associated acute kidney injury