#Acne vulgaris and risk of #depression and #anxiety: A meta-analytic review

Several studies have shown an association of acne vulgaris with depression and anxiety, but a quantitative review has not yet been conducted.. Forty-two studies were included. We found a significant association of acne vulgaris with depression ( r = 0.22 [95% confidence interval 0.17-0.26, P < .00001]) and anxiety ( r = 0.25 [95% confidence interval 0.19-0.31, P < .00001]). Subgroup analyses and comparisons showed … Continue reading #Acne vulgaris and risk of #depression and #anxiety: A meta-analytic review

Outcomes of Online #Mindfulness-Based Cognitive Therapy for Patients With Residual Depressive Symptoms A Randomized Clinical Trial

Patients with residual depressive symptoms face a gap in care because few resources, to date, are available to manage the lingering effects of their illness.. To evaluate the effectiveness for treating residual depressive symptoms with Mindful Mood Balance (MMB), a web-based application that delivers mindfulness-based cognitive therapy, plus usual depression care compared with usual depression care only. Participants who received MMB plus UDC had significantly … Continue reading Outcomes of Online #Mindfulness-Based Cognitive Therapy for Patients With Residual Depressive Symptoms A Randomized Clinical Trial

Assessment of a Prediction Model for Antidepressant Treatment Stability Using Supervised Topic Models

..Stable treatment response, intended as a proxy for treatment effectiveness, defined as continued prescription of an antidepressant for 90 days. Supervised topic models were used to extract 10 interpretable covariates from coded clinical data for stability prediction. With use of data from 1 hospital system (site A), generalized linear models and ensembles of decision trees were trained to predict stability outcomes from topic features that … Continue reading Assessment of a Prediction Model for Antidepressant Treatment Stability Using Supervised Topic Models

Effects of #yoga on depressive symptoms in people with mental disorders: a systematic review and meta-analysis

..Eligibility criteria for selecting studies We included randomised controlled trials with a yoga intervention comprising ≥50% physical activity in adults with a recognised diagnosed mental disorder according to DSM-3, 4 or 5. Results 19 studies were included in the review (1080 participants) and 13 studies were included in the meta-analysis (632 participants). Disorders of depression, post-traumatic stress, schizophrenia, anxiety, alcohol dependence and bipolar were included. … Continue reading Effects of #yoga on depressive symptoms in people with mental disorders: a systematic review and meta-analysis

#Circadian rhythm and sleep alterations in older people with lifetime #depression: a case-control study

Depression is common in older people and is associated with underlying brain change increasing the risk of dementia. Sleep disturbance is frequently reported by those with lifetime depression, however whether circadian misalignment also exists is unclear. We aimed to examine circadian rhythms and sleep associations in older patients with and without lifetime depression.. ..Participants underwent 2-weeks of actigraphy followed by a 3-night protocol including dim … Continue reading #Circadian rhythm and sleep alterations in older people with lifetime #depression: a case-control study

Inflammatory modulation of #fluoxetine use in patients with #depression: A systematic review and meta-analysis

There is growing evidence that there is a relationship between major depressive disorder (MDD), also simply known as “depression”, and inflammatory processes. Selective serotonin inhibitors, such as fluoxetine, are used as a first-line treatment for depression, and it is hypothesized that its use can reduce levels of proinflammatory cytokines. The aim of this systematic review and meta-analysis is to enable a better understanding of how … Continue reading Inflammatory modulation of #fluoxetine use in patients with #depression: A systematic review and meta-analysis

#Mood Homeostasis, Low Mood, and History of #Depression in 2 Large Population Samples

..To assess whether mood homeostasis (ie, the stabilization of one’s mood by engaging in mood-modifying activities) is a possible new therapeutic target by testing the hypothesis that people with low (vs high) mean mood and people with (vs without) a history of depression have impaired mood homeostasis.. ..A total of 28 212 participants from the 58sec data set (65.8% female; mean [SD] age, 28.1 [9.0] years) … Continue reading #Mood Homeostasis, Low Mood, and History of #Depression in 2 Large Population Samples

Association Between Lifetime Affective Symptoms and Premature Mortality

Associations between affective problems (anxiety and depression) and premature mortality have been demonstrated among psychiatric, medical, and community-based samples and across many causes of death.. ..Of 3001 study members (1509 [50.3%] female, 1492 [49.7%] male), 235 individuals (7.8%) died over a 15-year follow-up. After adjustment for sex, those who experienced case-level affective symptoms 1, 2, and 3 to 4 times had 76%, 87%, and 134% … Continue reading Association Between Lifetime Affective Symptoms and Premature Mortality

Factors Associated With #Mental Health Outcomes Among Health Care Workers Exposed to #Coronavirus Disease 2019

.. A total of 1257 of 1830 contacted individuals completed the survey, with a participation rate of 68.7%. A total of 813 (64.7%) were aged 26 to 40 years, and 964 (76.7%) were women. Of all participants, 764 (60.8%) were nurses, and 493 (39.2%) were physicians; 760 (60.5%) worked in hospitals in Wuhan, and 522 (41.5%) were frontline health care workers. A considerable proportion of … Continue reading Factors Associated With #Mental Health Outcomes Among Health Care Workers Exposed to #Coronavirus Disease 2019

Association of #Depression, #Anxiety, and Trauma With #Cannabis Use During Pregnancy

..Depression, anxiety, and trauma diagnoses and symptoms were associated with higher odds of cannabis use among pregnant women in California. These results support previous qualitative findings that pregnant women self-report using cannabis to manage mood and stress and suggest a dose-response association, with higher odds of cannabis use associated with co-occurring depressive and anxiety disorders and greater depression severity. However, research is needed to determine … Continue reading Association of #Depression, #Anxiety, and Trauma With #Cannabis Use During Pregnancy

Thalamic Gamma Aminobutyric Acid Level Changes in Major #Depressive Disorder After a 12-Week Iyengar Yoga and Coherent #Breathing Intervention

To determine if a 12-week yoga intervention (YI) was associated with increased gamma aminobutyric acid (GABA) levels and decreased depressive symptoms in participants with major depressive disorder (MDD). Subjects were randomized to a high-dose group (HDG) of three YIs a week and a low-dose group (LDG) of two YIs a week. ..BDI-II scores improved significantly in both groups. GABA levels from Scan-1 to Scan-3 and … Continue reading Thalamic Gamma Aminobutyric Acid Level Changes in Major #Depressive Disorder After a 12-Week Iyengar Yoga and Coherent #Breathing Intervention

#Depressive symptoms and objectively measured physical activity and #sedentary behaviour throughout adolescence: a prospective cohort study

..Higher depression scores at 18 years were associated with a 60 min/day increase in sedentary behaviour at 12 years (incidence rate ratio [IRR] 1·111 [95% CI 1·051–1·176]), 14 years (1·080 [1·012–1·152]), and 16 years of age (1·107 [1·015–1·208]). Depression scores at 18 years were lower for every additional 60 min/day of light activity at 12 years (0·904 [0·850–0·961]), 14 years (0·922 [0·857–0·992]), and 16 years … Continue reading #Depressive symptoms and objectively measured physical activity and #sedentary behaviour throughout adolescence: a prospective cohort study