To investigate the preliminary efficacy of a high n-3 plus low n-6 (H3-L6) dietary intervention in improving mood stability in Bipolar Disorder (BD) when compared to dietary intervention with usual U.S. levels of n-6 and n-3 polyunsaturated fatty acid (PUFA) intakes (control diet, CD). MethodsThis 2-arm, parallel-group, randomized, modified double-blind, controlled 48-week study of 12-week … Continue reading Adjunctive #dietary intervention for #bipolar disorder: a randomized, controlled, parallel-group, modified double-blinded trial of a high n-3 plus low n-6 diet
Tag: Diet
Recent human feeding studies have shown how the baseline taxonomic composition of the gut microbiome can determine responses to weight loss interventions. However, the functional determinants underlying this phenomenon remain unclear. We report a weight loss response analysis on a cohort of 105 individuals selected from a larger population enrolled in a commercial wellness program, … Continue reading Baseline #Gut Metagenomic Functional Gene Signature Associated with Variable #Weight Loss Responses following a Healthy Lifestyle Intervention in Humans
Temporal partitioning of daily food intake is crucial for survival and involves the integration of internal circadian states and external influences such as the light-dark cycle and dietary composition. These intrinsic and extrinsic factors are interdependent with misalignment of circadian rhythms promoting body weight gain, while consumption of a calorie dense diet elevates the risk … Continue reading Rhythmic neuronal activities of the rat nucleus of the solitary tract are impaired by high- #fat diet – implications for daily control of #satiety
We assessed, for the first time, to what extent the composition of the gut microbiome might explain the cross-sectional association of habitual flavonoid and flavonoid-rich food intake with systolic and diastolic blood pressure (BP) in a community-based sample (N=904) from Northern Germany. Gut microbiome composition was sequenced from 16S ribosomal RNA genes. Higher total flavonoid … Continue reading Microbial Diversity and Abundance of Parabacteroides Mediate the Associations Between Higher Intake of #Flavonoid-Rich Foods and Lower Blood #Pressure
