Effectiveness and Safety of #Apixaban Compared With #Rivaroxaban for Patients With Atrial Fibrillation in Routine Practice: A Cohort Study

Apixaban and rivaroxaban are the most commonly prescribed direct oral anticoagulants for adults with atrial fibrillation, but head-to-head data comparing their safety and effectiveness are lacking.. 39 351 patients newly prescribed apixaban were propensity score matched to 39 351 patients newly prescribed rivaroxaban. Mean age was 69 years, 40% of patients were women, and mean follow-up was 288 days for new apixaban users and 291 … Continue reading Effectiveness and Safety of #Apixaban Compared With #Rivaroxaban for Patients With Atrial Fibrillation in Routine Practice: A Cohort Study

Changes in atrial #fibrillation admissions following #daylight saving time transitions

Daylight saving time (DST) imposes a twice-yearly hour shift. The transitions to and from DST are associated with decreases in sleep quality and environmental hazards. Detrimental health effects include increased incidence of acute myocardial infarction (MI) following the springtime transition and increased ischemic stroke following both DST transitions. Conditions effecting sleep are known to provoke atrial fibrillation (AF), however the effect of DST transitions on … Continue reading Changes in atrial #fibrillation admissions following #daylight saving time transitions

Persistent #Asthma is Associated with Increased Risk for Incident Atrial #Fibrillation in the Multi-Ethnic Study of Atherosclerosis (MESA)

Asthma and atrial fibrillation (AF) share an underlying inflammatory pathophysiology. We hypothesized that persistent asthmatics are at higher risk for developing AF and that this association would be attenuated by adjustment for baseline markers of systemic inflammation. ..Persistent asthma was defined as asthma requiring use of controller medications. Intermittent asthma was defined as asthma without use of controller medications.. ..In risk-factor adjusted models, persistent asthmatics … Continue reading Persistent #Asthma is Associated with Increased Risk for Incident Atrial #Fibrillation in the Multi-Ethnic Study of Atherosclerosis (MESA)

Direct Oral #Anticoagulants in Atrial Fibrillation Patients with Concomitant #Hyperthyroidism

Patients with hyperthyroidism were excluded from randomized clinical trials of direct oral anticoagulants(DOACs) for stroke prevention in patients with non-valvular atrial fibrillation (NVAF).. After PSSW, DOAC had a comparable risk of ischemic stroke/systemic embolism (IS/SE) and a lower risk of major bleeding (hazard ratio (HR):0.65; [95% confidential interval (CI):0.44-0.96]; P=0.0295) than warfarin among patients with hyperthyroidism. There were comparable risks of IS/SE and major bleeding … Continue reading Direct Oral #Anticoagulants in Atrial Fibrillation Patients with Concomitant #Hyperthyroidism

Improved #oral hygiene care is associated with decreased risk of occurrence for atrial #fibrillation and heart #failure: A nationwide population-based cohort study

Poor oral hygiene can provoke transient bacteremia and systemic inflammation, a mediator of atrial fibrillation and heart failure.. .. In multivariate analysis after adjusting age, sex, socioeconomic status, regular exercise, alcohol consumption, body mass index, hypertension, diabetes, dyslipidemia, current smoking, renal disease, history of cancer, systolic blood pressure, blood and urine laboratory findings, frequent tooth brushing (≥3 times/day) was significantly associated with attenuated risk of … Continue reading Improved #oral hygiene care is associated with decreased risk of occurrence for atrial #fibrillation and heart #failure: A nationwide population-based cohort study

Taller people have increased risk for developing atrial #fibrillation

Researchers found that the risk for AFib climbed as one’s height increased, with every one-inch increase in height translating to about a three percent increase in risk of Afib–independent of other clinical factors–as compared to those at average height (5 feet and 7 inches). “Our findings suggest it may be beneficial to incorporate height into risk-prediction tools for AFib,” said the study’s lead author Michael … Continue reading Taller people have increased risk for developing atrial #fibrillation