Persistent #Asthma is Associated with Increased Risk for Incident Atrial #Fibrillation in the Multi-Ethnic Study of Atherosclerosis (MESA)

Asthma and atrial fibrillation (AF) share an underlying inflammatory pathophysiology. We hypothesized that persistent asthmatics are at higher risk for developing AF and that this association would be attenuated by adjustment for baseline markers of systemic inflammation. ..Persistent asthma was defined as asthma requiring use of controller medications. Intermittent asthma was defined as asthma without use of controller medications.. ..In risk-factor adjusted models, persistent asthmatics … Continue reading Persistent #Asthma is Associated with Increased Risk for Incident Atrial #Fibrillation in the Multi-Ethnic Study of Atherosclerosis (MESA)

Long #Working Hours and the Prevalence of Masked and Sustained #Hypertension

Previous studies on the effect of long working hours on blood pressure have shown inconsistent results. Mixed findings could be attributable to limitations related to blood pressure measurement and the lack of consideration of masked hypertension.. Ambulatory blood pressure was defined as the mean of the next readings recorded every 15 minutes during daytime working hours. Masked hypertension was defined as clinic blood pressure < … Continue reading Long #Working Hours and the Prevalence of Masked and Sustained #Hypertension

FDA Authorizes Marketing of First Cardiac #Ultrasound Software That Uses Artificial #Intelligence to Guide User

..the U.S. Food and Drug Administration authorized marketing of software to assist medical professionals in the acquisition of cardiac ultrasound, or echocardiography, images. The software, called Caption Guidance, is an accessory to compatible diagnostic ultrasound systems and uses artificial intelligence to help the user capture images of a patient’s heart that are of acceptable diagnostic quality. The Caption Guidance software is indicated for use in … Continue reading FDA Authorizes Marketing of First Cardiac #Ultrasound Software That Uses Artificial #Intelligence to Guide User

Direct Oral #Anticoagulants in Atrial Fibrillation Patients with Concomitant #Hyperthyroidism

Patients with hyperthyroidism were excluded from randomized clinical trials of direct oral anticoagulants(DOACs) for stroke prevention in patients with non-valvular atrial fibrillation (NVAF).. After PSSW, DOAC had a comparable risk of ischemic stroke/systemic embolism (IS/SE) and a lower risk of major bleeding (hazard ratio (HR):0.65; [95% confidential interval (CI):0.44-0.96]; P=0.0295) than warfarin among patients with hyperthyroidism. There were comparable risks of IS/SE and major bleeding … Continue reading Direct Oral #Anticoagulants in Atrial Fibrillation Patients with Concomitant #Hyperthyroidism

Associations of Processed #Meat, Unprocessed Red Meat, Poultry, or #Fish Intake With Incident #Cardiovascular Disease and All-Cause Mortality

Although the associations between processed meat intake and cardiovascular disease (CVD) and all-cause mortality have been established, the associations of unprocessed red meat, poultry, or fish consumption with CVD and all-cause mortality are still uncertain.. .. Intake of processed meat (adjusted HR, 1.03 [95% CI, 1.02-1.05]; adjusted ARD, 0.90% [95% CI, 0.43%-1.38%]) or unprocessed red meat (adjusted HR, 1.03 [95% CI, 1.01-1.05]; adjusted ARD, 0.76% … Continue reading Associations of Processed #Meat, Unprocessed Red Meat, Poultry, or #Fish Intake With Incident #Cardiovascular Disease and All-Cause Mortality

Updating insights into #rosiglitazone and cardiovascular risk through shared data: individual patient and summary level meta-analyses

individual patient level data (IPD) ..The odds ratios for myocardial infarction, heart failure, cardiovascular related death, and non-cardiovascular related death were 1.17 (0.92 to 1.51), 1.54 (1.14 to 2.09), 1.15 (0.55 to 2.41), and 1.18 (0.60 to 2.30), respectively. For analyses including trials for which IPD were not available, odds ratios for myocardial infarction and cardiovascular related death were attenuated (1.09, 0.88 to 1.35, and … Continue reading Updating insights into #rosiglitazone and cardiovascular risk through shared data: individual patient and summary level meta-analyses

Updating insights into #rosiglitazone and #cardiovascular risk through shared data: individual patient and summary level meta-analyses

..The odds ratios for myocardial infarction, heart failure, cardiovascular related death, and non-cardiovascular related death were 1.17 (0.92 to 1.51), 1.54 (1.14 to 2.09), 1.15 (0.55 to 2.41), and 1.18 (0.60 to 2.30), respectively. For analyses including trials for which IPD were not available, odds ratios for myocardial infarction and cardiovascular related death were attenuated (1.09, 0.88 to 1.35, and 1.12, 0.72 to 1.74, respectively). … Continue reading Updating insights into #rosiglitazone and #cardiovascular risk through shared data: individual patient and summary level meta-analyses

#Lifestyle Changes in Relation to Initiation of #Antihypertensive and #Lipid‐Lowering Medication: A Cohort Study

Lifestyle modification is a key component of cardiovascular disease prevention before and concurrently with pharmacologic interventions.. ..In participants who initiated medication use, body mass index increased more (difference in change 0.19; 95% CI, 0.16–0.22) and physical activity declined (−0.09 metabolic equivalent of task hour/day; 95% CI, −0.16 to −0.02) compared with noninitiators. The likelihood of becoming obese (odds ratio: 1.82; 95% CI, 1.63–2.03) and physically … Continue reading #Lifestyle Changes in Relation to Initiation of #Antihypertensive and #Lipid‐Lowering Medication: A Cohort Study

Early onset of #menopause is associated with increased peripheral #atherosclerotic plaque volume and progression

Cardiovascular disease (CVD) is the leading cause of death in western countries. One risk factor unique to women is the menopausal status. The aim of this study was to analyse the influence of the onset of menopause (MP) on the extent and progression of atherosclerotic plaque volume (PV). ..110 consecutive postmenopausal women (mean age 65.5) were included. Females with an earlier onset of MP (<45 … Continue reading Early onset of #menopause is associated with increased peripheral #atherosclerotic plaque volume and progression

#Pet Ownership and #Cardiovascular Health in the US general population

The 2013 American Heart Association Scientific Statement on pet ownership and cardiovascular risk suggested that dog ownership is probably associated with decreased cardiovascular risk. Several studies have been shown that pet ownership, particularly of dogs, is associated with increased physical activity levels, social support, and improved outcomes after a major cardiovascular event.. Pet owners were older, less likely to be women or widowed, and more … Continue reading #Pet Ownership and #Cardiovascular Health in the US general population

#Marijuana Use in Patients With #Cardiovascular Disease: JACC Review Topic of the Week

Marijuana use is increasing as more states are legalizing cannabis for both medicinal and recreational purposes. National survey data estimate that >2 million Americans with established cardiovascular diseases currently use or have used marijuana in its variety of forms, including inhalation and vaping. Cannabinoid receptors are distributed in multiple tissue beds and cells, including platelets, adipose tissue, and myocytes. Observational data suggest associations between marijuana … Continue reading #Marijuana Use in Patients With #Cardiovascular Disease: JACC Review Topic of the Week