Lower fasting-ghrelin-levels (FGL) are associated with obesity and metabolic syndrome. We aimed to explore the dynamics of FGL during weight-loss and its metabolic and adiposity-related manifestations beyond weight-loss. MethodsA secondary analysis of a clinical trial where we randomized participants with abdominal-obesity/dyslipidemia to one of three diets: healthy-dietary-guidelines (HDG), Mediterranean diet (MED), or green-MED diet, all … Continue reading #Diet-induced #fasting ghrelin elevation reflects the recovery of #insulin sensitivity and visceral adiposity regression
Tag: physical-activity
Data on the lifetime risk of type 2 diabetes (T2D) incidence across different cardiovascular health (CVH) categories are scarce. Moreover, it remains unclear whether a genetic predisposition modifies this association. Methods and resultsUsing data from the prospective population-based Rotterdam Study, a CVH score (body mass index, blood pressure, total cholesterol, smoking status, diet, and physical … Continue reading Cardiovascular health, genetic predisposition, and lifetime risk of type 2 #diabetes
We propose a weight-neutral strategy for obesity treatment on the following grounds: (1) the mortality risk associated with obesity is largely attenuated or eliminated by moderate-to-high levels of cardiorespiratory fitness (CRF) or physical activity (PA), (2) most cardiometabolic risk markers associated with obesity can be improved with exercise training independent of weight loss and by … Continue reading #Obesity treatment: #Weight loss versus increasing #fitness and physical activity for reducing health risks
Poor social health is a risk factor for cardiovascular disease (CVD), however an in-depth exploration of the link through CVD risk factors is lacking. AimTo examine the relationship between social health (social isolation, social support, loneliness) and CVD risk factors among healthy older women and men. MethodsData were from 11,498 healthy community-dwelling Australians aged ≥70 … Continue reading #Social Health and #Cardiovascular Disease Risk Factors: A cross-sectional study in a healthy older adult population
A healthy brain is critical for living a longer and fuller life. The projected aging of the population, however, raises new challenges in maintaining quality of life. As we age, there is increasing compromise of neuronal activity that affects functions such as cognition, also making the brain vulnerable to disease. Once pathology-induced decline begins, few … Continue reading A Primary Care Agenda for #Brain Health: A Scientific Statement From the American Heart Association
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