Vitamin D supplementation has been widely recommended to prevent falls. However, considerable controversy exists regarding the association of such supplementation and fall risk. Previous meta-analyses yielded inconsistent results because of differences in the baseline of 25-hydroxyvitamin D (25[OH]D) and dose of vitamin D and use of vitamin D or in combination with calcium in different … Continue reading Vitamin #D supplementation reduces the risk of #fall in the vitamin D deficient elderly: an updated systematic review and meta-analysis
Category: Gerontology
Severe hypoglycemia requiring access to the Emergency Department is more frequent in older patients with multiple comorbidities.•Risk of hospitalization and mortality within one year since the hypoglycemic event is higher in older frail patients.•Severe hypoglycemia could increase the cardiovascular risk and could be a marker of future cardiovascular events.•A less stringent glycemic control and the … Continue reading #Aging and comorbidities influence the risk of hospitalization and mortality in #diabetic patients experiencing severe hypoglycemia
To determine whether lower serum albumin in community-dwelling, older adults is associated with increased risk of hospitalization and death independent of pre-existing disease. DesignProspective cohort study of participants in the fifth visit of the Atherosclerosis Risk in Communities (ARIC) study. Baseline data were collected from 2011 to 2013. Follow-up was available to December 31, 2017. … Continue reading Serum #albumin and risks of hospitalization and death: Findings from the #Atherosclerosis Risk in Communities study
Sarcopenia comprises a loss of muscle function and muscle mass. So far, the association between the later and mortality in older adults is inconsistent. A meta-analysis was performed to assess whether muscle mass measured by appendicular skeletal muscle mass index (ASMI) is associated with higher mortality in older adults. Articles of interest were searched for … Continue reading Low #muscle mass in #older adults and mortality: A systematic review and meta-analysis
Hypoxia drives aging and promotes age-related cognition and hearing functional decline. Despite the role of erythrocytes in oxygen (O2) transport, their role in the onset of aging and age-related cognitive decline and hearing loss (HL) remains undetermined. Recent studies revealed that signaling through the erythrocyte adenosine A2B receptor (ADORA2B) promotes O2 release to counteract hypoxia … Continue reading #Erythrocyte adenosine A2B receptor prevents #cognitive and #auditory dysfunction by promoting hypoxic and metabolic reprogramming
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