Light-to-moderate alcohol consumption has been reported to be cardio-protective among apparently healthy individuals; however, it is unclear whether this association is also present in those with disease. To examine the association between alcohol consumption and prognosis in individuals with pre-existing cardiovascular disease (CVD), we conducted a series of meta-analyses of new findings from three large-scale … Continue reading Association of #alcohol consumption with morbidity and mortality in patients with #cardiovascular disease: original data and meta-analysis of 48,423 men and women
Tag: Alcohol
The SALVE Histopathology Group (SHG) developed and validated a grading and staging system for the clinical and full histological spectrum of alcohol-related liver disease (ALD) and evaluated its prognostic utility in a multinational cohort of 445 patients. MethodsSALVE grade was described by semiquantitative scores for steatosis, activity (hepatocellular injury and lobular neutrophils) and cholestasis. The … Continue reading Development and prognostic relevance of a histologic grading and staging system for #alcohol-related #liver disease
Having a family member with an alcohol use disorder (AUD) may negatively affect a person’s health. Our aim was to study the long-term risk of coronary heart disease (CHD) in parents who have an offspring with AUD. DesignCohort study. Cox regression models and co-sibling analyses. SettingSweden. ParticipantsFrom population registers, we selected all parent-offspring pairs in … Continue reading #Coronary heart disease in mothers and fathers of adult children with #alcohol use disorders
Aims1) Estimate the effect of extended-release naltrexone compared with placebo on alcohol consumption in patients with alcohol use disorder (AUD). 2) Conduct pre-planned subgroup analyses to test whether being abstinent when initiating treatment (lead-in abstinence) or the duration of treatment improves treatment efficacy. DesignSystematic review and random effects meta-analysis of blinded randomized placebo-controlled trials reporting … Continue reading Effect of Extended-Release #Naltrexone on #Alcohol Consumption: A Systematic Review and Meta-analysis
