Contribution of Common Genetic Variants to Risk of Early Onset Ischemic Stroke

Background and Objectives:Β Current genome-wide association studies of ischemic stroke have focused primarily on late onset disease. As a complement to these studies, we sought to identifythe contribution of common genetic variants to risk of early onset ischemic stroke.Methods:Β We performed a meta-analysis of genome-wide association studies of early onset stroke (EOS), ages 18-59, using individual level …

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Laparoscopically Confirmed Endometriosis and Risk of Incident Stroke: A Prospective Cohort Study

AbstractBackground:Prior research suggests that women with endometriosis are at greater risk of coronary heart disease. Therefore, our objective was to prospectively investigate the association between laparoscopically confirmed endometriosis and risk of incident stroke during 28 years of follow-up.Methods:Participants in the NHSII cohort study (Nurses’ Health Study II) were followed from 1989 when they were between …

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Acute ischemic stroke and vaccine-induced immune thrombotic thrombocytopenia post COVID-19 vaccination; a systematic review

AbstractIntroductionOne of the rare but potentially serious side effects of COVID-19 vaccination is arterial and venous thrombosis. Acute ischemic stroke (AIS) cases have been reported post COVID-19 vaccination. Herein, we systematically reviewed the reported cases of AIS after COVID-19 vaccination.MethodThis systematic review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses …

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Association of Accelerometer-Measured Sedentary Time and Physical Activity With Risk of Stroke Among US Adults

Importance The amount and intensity of physical activity required to prevent stroke are yet to be fully determined because of previous reliance on self-reporting measures. Furthermore, the association between objectively measured time spent being sedentary as an independent risk factor for stroke is unknown. Objective To investigate the associations of accelerometer-measured sedentary time and physical …

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Supper Timing and Cardiovascular Mortality: The Japan Collaborative Cohort Study

Evidence on the role of supper timing in the development of cardiovascular disease (CVD) is limited. In this study, we examined the associations between supper timing and risks of mortality from stroke, coronary heart disease (CHD), and total CVD. A total of 28,625 males and 43,213 females, aged 40 to 79 years, free from CVD …

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