Buongiorno! My name is Aldo and I am an Internal Medicine Doctor. This is my Medical News Blog and I'm sure you'll find it useful and informative. All the articles can be searched by Category, Tag or Text. Just click on a post or on the Search link above.
Efficacy and safety of MIPO versus ORIF in distal tibial fractures: a systematic review and meta-analysis
Background: Distal tibial fractures are challenging to manage owing to limited soft-tissue coverage and compromised blood supply. Minimally invasive plate osteosynthesis (MIPO) and open reduction and internal fixation (ORIF) are among the widely used surgical options, but the optimal approach remains unclear. MIPO preserves periosteal blood flow with smaller incisions, while ORIF offers direct visualisation… Continue reading Efficacy and safety of MIPO versus ORIF in distal tibial fractures: a systematic review and meta-analysis
The Evolving Landscape of Clinical Aging Clocks: From Epigenetic to Multi-Omics Integration
Aging clocks are tools that quantify biological #aging through the integration of multi-omics data, encompassing epigenetic, transcriptomic, proteomic, metabolic, and microbial information, together with functional biomarkers. These tools show significant potential for use in preventive medicine, early detection of chronic conditions, and monitoring the effectiveness of interventions designed to enhance population health. The advancement of… Continue reading The Evolving Landscape of Clinical Aging Clocks: From Epigenetic to Multi-Omics Integration
Impact of β-blocker therapy after acute myocardial infarction in patients with preserved ejection fraction: a meta-analysis
Introduction: Despite earlier evidence, the benefit of long-term #β-blockers after myocardial infarction (MI) in patients with preserved or mildly reduced ejection fraction remains unclear in the modern reperfusion era.Methods: We conducted a PRISMA-guided systematic review and meta-analysis by searching the PubMed, Google Scholar, and Cochrane databases, pooling results using a random effects model with 95%… Continue reading Impact of β-blocker therapy after acute myocardial infarction in patients with preserved ejection fraction: a meta-analysis
Lipid ratios as early screening markers of dyslipidemia in normal-BMI university students: a cross-sectional epidemiologic study
Introduction: This study aimed to determine the prevalence of #dyslipidemia and to assess the predictive performance of lipid ratios, specifically the #Atherogenic Index of Plasma (AIP) and the total #cholesterol (TC) to high-density lipoprotein cholesterol (HDL-C) (TC/HDL) ratio, compared to body mass index (BMI) in identifying dyslipidemia among non-obese male university students.Material and methods: A… Continue reading Lipid ratios as early screening markers of dyslipidemia in normal-BMI university students: a cross-sectional epidemiologic study
Exploring the link between water-soluble vitamins and aging-associated immune system status
Background: #Aging is associated with numerous physiological changes that contribute to immunosenescence and inflammaging, resulting in a decline in immune defense and an increased susceptibility to infections. Older adults are at risk of inadequate dietary intake and suboptimal supply of micronutrients, including water-soluble #vitamins, even those generally considered sufficient in the overall population. These deficiencies… Continue reading Exploring the link between water-soluble vitamins and aging-associated immune system status
A retrospective study on the safety of small and large volume paracentesis and risk factors for adverse events in patients with gastrointestinal cancer with malignant ascites
Background: The optimal drainage volume for #paracentesis in malignant #ascites (MA) has not been established, and identifying risk factors for paracentesis may serve as a guideline for clinical decisions regarding drainage volume in MA patients. Therefore, the aim of this study is to compare the safety of small-volume drainage (SVD) versus large-volume drainage (LVD) in… Continue reading A retrospective study on the safety of small and large volume paracentesis and risk factors for adverse events in patients with gastrointestinal cancer with malignant ascites
Effect of relative handgrip strength and back muscle strength on the incidence of hypertension: 18-year follow-up in a population-based cohort study
Substantial evidence supports an association between physical #exercises and #hypertension. However, the role of muscle #strength, such as hand grip strength (HGS) and back muscle strength (BMS), remains unclear in this relationship. This study investigated whether low BMS and HGS accelerated incident hypertension in a population-based prospective study. A total 3,038 non-hypertensive subjects aged 40-69… Continue reading Effect of relative handgrip strength and back muscle strength on the incidence of hypertension: 18-year follow-up in a population-based cohort study
Prognostic value of C-reactive protein to albumin ratio for in-hospital mortality in acute stroke patients
Background: This study aimed to evaluate the prognostic significance of the C-reactive protein to albumin ratio (CAR) in predicting in-hospital #mortality among patients presenting with acute #stroke.Method: A total of 483 adult patients (≥ 18 years) consecutively hospitalized for stroke over a one-year period (July 2022 - July 2023) were analyzed retrospectively. Exclusion criteria include… Continue reading Prognostic value of C-reactive protein to albumin ratio for in-hospital mortality in acute stroke patients
Bridging the Gap: Using an Asynchronous E-Learning Module to Improve Internal Medicine Residents’ Confidence and Preparedness in Ambulatory Blood Pressure Monitoring Interpretation
Background: Ambulatory blood #pressure monitoring (ABPM) is considered a reference standard for diagnosing #hypertension and is recommended for out-of-office blood pressure assessment, yet internal medicine residents receive limited training in its interpretation. We conducted a needs assessment to identify gaps in hypertension and ABPM education and developed an asynchronous e-learning module to address these deficiencies.… Continue reading Bridging the Gap: Using an Asynchronous E-Learning Module to Improve Internal Medicine Residents’ Confidence and Preparedness in Ambulatory Blood Pressure Monitoring Interpretation
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