Foreword

Buongiorno! Guten Tag! Good Morning!
My name is Aldo, I am a physician and I live in Milano, Italy. I have always read a lot of medical news, and I have realised how difficult it is to forget to read those news if you’re not disciplined enough or if you don’t make that a habit. So I have decided to help myself and the community, here and on the Telegram app, and share just two articles daily, those that get my attention. All the articles can be searched by Category or Tag.

Buona Lettura! Continue reading Foreword

Effect of Vitamin #D and ω-3 #Fatty Acid Supplementation on Risk of Age-Related #Macular Degeneration An Ancillary Study of the VITAL Randomized Clinical Trial

Observational studies suggest that higher intake or blood levels of vitamin D and marine ω-3 fatty acids may be associated with lower risks of age-related macular degeneration (AMD). However, evidence from randomized trials is limited.. ..In total, 25 871 participants with a mean (SD) age of 67.1 (7.0) years were included in the trial. Of them, 50.6% were women, 71.3% were self-declared non-Hispanic White participants, and … Continue reading Effect of Vitamin #D and ω-3 #Fatty Acid Supplementation on Risk of Age-Related #Macular Degeneration An Ancillary Study of the VITAL Randomized Clinical Trial

Air #pollution as a determinant of food delivery and related #plastic waste

Plastic waste is a growing environmental concern. The food delivery industry is criticized for its environmental impact, especially its current use of plastic packaging. At the same time, the environment impacts the industry. We show that air pollution is a behavioural driver of food delivery consumption in the urban developing world. Our hypothesis is that individuals are more likely to order delivery when their personal … Continue reading Air #pollution as a determinant of food delivery and related #plastic waste

Inadequate #Physical Activity and #Sedentary Behavior Are Independent Predictors of Nonalcoholic Fatty #Liver Disease

In general, physical activity (PA) and nonalcoholic fatty liver disease (NAFLD) have an inverse association. However, studies assessing the impact of the widely accepted Physical Activity Guidelines for Americans (PA Guidelines) on NAFLD are lacking. We performed a serial, cross‐sectional analysis among adults by using the 2007‐2016 US National Health and Nutrition Examination Survey. NAFLD and advanced fibrosis were defined by using various noninvasive panels. … Continue reading Inadequate #Physical Activity and #Sedentary Behavior Are Independent Predictors of Nonalcoholic Fatty #Liver Disease

Residential context and #COVID-19 mortality among adults aged 70 years and older in Stockholm: a population-based, observational study using individual-level data

Housing characteristics and neighbourhood context are considered risk factors for COVID-19 mortality among older adults. The aim of this study was to investigate how individual-level housing and neighbourhood characteristics are associated with COVID-19 mortality in older adults.. ..Of 279 961 individuals identified to be aged 70 years or older on March 12, 2020, and residing in Stockholm in December, 2019, 274 712 met the eligibility criteria and … Continue reading Residential context and #COVID-19 mortality among adults aged 70 years and older in Stockholm: a population-based, observational study using individual-level data

Association of Therapies With Reduced #Pain and Improved Quality of Life in Patients With #Fibromyalgia

..To investigate the effectiveness of therapies for reducing pain and improving quality of life (QOL) in people with fibromyalgia.. ..A total of 224 trials including 29 962 participants were included. High-quality evidence was found in favor of cognitive behavioral therapy (weighted mean difference [WMD], −0.9; 95% CI, −1.4 to −0.3) for pain in the short term and was found in favor of central nervous system depressants … Continue reading Association of Therapies With Reduced #Pain and Improved Quality of Life in Patients With #Fibromyalgia

Sex, age, and hospitalization drive #antibody responses in a #COVID-19 convalescent plasma donor population

Convalescent plasma is a leading treatment for coronavirus disease 2019 (COVID-19), but there is a paucity of data identifying its therapeutic efficacy. Among 126 potential convalescent plasma donors, the humoral immune response was evaluated using a severe acute respiratory syndrome coronavirus 2 (SARS–CoV-2) virus neutralization assay with Vero-E6-TMPRSS2 cells; a commercial IgG and IgA ELISA to detect the spike (S) protein S1 domain (EUROIMMUN); IgA, … Continue reading Sex, age, and hospitalization drive #antibody responses in a #COVID-19 convalescent plasma donor population

#Periodontal Inflammation Primes the Systemic Innate #Immune Response

The presence of periodontal diseases (PDs) often strongly correlates with other severe chronic inflammatory conditions, including cardiovascular disease, diabetes, and arthritis. However, the mechanisms through which these diseases interact are unclear. In PD, tissue and bone destruction in the mouth is driven by elevated recruitment of polymorphonuclear neutrophils (PMNs), which are primed and recruited from the circulation to sites of inflammation. We predicted that systemic … Continue reading #Periodontal Inflammation Primes the Systemic Innate #Immune Response

Effect of Finerenone on Chronic Kidney Disease Outcomes in Type 2 Diabetes

Finerenone, a nonsteroidal, selective mineralocorticoid receptor antagonist, reduced albuminuria in short-term trials involving patients with chronic kidney disease (CKD) and type 2 diabetes. However, its long-term effects on kidney and cardiovascular outcomes are unknown. ..During a median follow-up of 2.6 years, a primary outcome event occurred in 504 of 2833 patients (17.8%) in the finerenone group and 600 of 2841 patients (21.1%) in the placebo … Continue reading Effect of Finerenone on Chronic Kidney Disease Outcomes in Type 2 Diabetes

#Acupuncture of different treatment frequencies in knee #osteoarthritis: a pilot randomised controlled trial

This 16-week randomised controlled trial (8-week treatment followed by 8-week follow-up) evaluated the symptomatic improvement in patients with knee osteoarthritis on 3 sessions per week of acupuncture (TSWA) compared to 1 session per week of acupuncture (OSWA). Sixty participants were randomised to either the TSWA or the OSWA group in a 1:1 ratio. The primary outcome was response rate, defined as the percentage of participants … Continue reading #Acupuncture of different treatment frequencies in knee #osteoarthritis: a pilot randomised controlled trial

#Empagliflozin treatment effects across categories of baseline #HbA1c, body #weight and blood #pressure as an add‐on to metformin in patients with type 2 diabetes

In EMPA‐REG MET, in patients with type 2 diabetes mellitus (T2DM) on stable background metformin (≥1500 mg/day), empagliflozin versus placebo significantly improved glycated haemoglobin (HbA1c), body weight (BW), and systolic blood pressure (SBP) over 24 and ≤76 weeks. This analysis investigated empagliflozin treatment effects by baseline cardio‐metabolic factors.. ..In total, 637 patients (56.7% males; mean [SD] age 55.7 [9.9] years, HbA1c 7.9 [0.9] %, BW 81.2 … Continue reading #Empagliflozin treatment effects across categories of baseline #HbA1c, body #weight and blood #pressure as an add‐on to metformin in patients with type 2 diabetes

#BMI and All‐Cause #Mortality in a Population‐Based Cohort in Rural South Africa

..The cohort consisted of 9,728 individuals. In adjusted models, those with BMI of 25.0 to 29.9 kg/m2 or 30.0 to 34.9 kg/m2 had a lower hazard of death (adjusted hazard ratio: 0.80; 95% CI: 0.69‐0.92 and adjusted hazard ratio: 0.75; 95% CI: 0.60‐0.93, respectively) compared with those with BMI of 18.5 to 24.9 kg/m2. Conclusions Individuals in South Africa who meet clinically defined criteria for … Continue reading #BMI and All‐Cause #Mortality in a Population‐Based Cohort in Rural South Africa

Trends in #Physician #Voting Practices in California, New York, and Texas, 2006-2018

From 1996 to 2002, eligible physicians voted approximately 9 percentage points less than the general population.1 Since then, physician voter engagement has not been reported. We investigated physician voter participation, voter registration, and voter turnout from 2006 through 2018 in California, New York, and Texas, which are states with the largest number of physicians.. ..Discussion From 2006 through 2018, voter participation among eligible physicians in … Continue reading Trends in #Physician #Voting Practices in California, New York, and Texas, 2006-2018