Buongiorno! My name is Aldo and I am an Internal Medicine Doctor. This is my Medical News Blog and I'm sure you'll find it useful and informative. All the articles can be searched by Category, Tag or Text. Just click on a post or on the Search link above.
Renal denervation triage tool: a practical approach to the management of resistant hypertension
Despite the availability of medications and advocacy for lifestyle interventions, over half of individuals with hypertension do not achieve recommended treatment goals owing to limitations with medications, such as high cost, side effects, and poor adherence. Renal denervation (RDN), a minimally invasive endovascular procedure targeting sympathetic nerves near the renal arteries, is gaining recognition as… Continue reading Renal denervation triage tool: a practical approach to the management of resistant hypertension
Role of homocysteine, vitamins B12, B6, B1, and folate in Saudi patients with premature acute coronary syndrome
Homocysteine (HCY) has been implicated in cardiovascular disease through adverse effects on vascular endothelium, oxidative stress, and thrombogenic pathways. Saudi Arabia has a young population and an increasing burden of cardiovascular disease, yet regional data on HCY and B-vitamin profiles in premature acute coronary syndrome (ACS) remain limited. This single-center cross-sectional exploratory study evaluated serum… Continue reading Role of homocysteine, vitamins B12, B6, B1, and folate in Saudi patients with premature acute coronary syndrome
Ovarian Hyperstimulation Syndrome: An Unusual Cause of Abdominal Pain Presenting to the Emergency Department
The use of assisted reproductive technologies (ART), such as in vitro fertilization (IVF), is steadily increasing. Ovarian hyperstimulation syndrome (OHSS) is a rare but potentially serious complication arising from controlled ovarian hyperstimulation (COH), a critical component of ART. OHSS may vary in severity and usually causes abdominal pain, nausea, vomiting, diarrhea, and dyspnea, which are… Continue reading Ovarian Hyperstimulation Syndrome: An Unusual Cause of Abdominal Pain Presenting to the Emergency Department
Association Between Helicobacter pylori Infection and Iron Deficiency Anemia in Adult Patients Attending a Tertiary Care Hospital
Background: Iron deficiency anemia (IDA) has been increasingly associated with Helicobacter pylori (H. pylori) infection, especially in developing countries.Objective: This study aimed to evaluate the association between H. pylori infection and IDA severity and to compare hematological parameters between H. pylori-positive and -negative adult patients attending a tertiary care hospital.Methodology: This was a cross-sectional analytical… Continue reading Association Between Helicobacter pylori Infection and Iron Deficiency Anemia in Adult Patients Attending a Tertiary Care Hospital
Toward Precision Aspirin Prophylaxis: Optimal Aspirin Dosing For Prevention of Preeclampsia
Purpose of review: To review contemporary evidence regarding optimal aspirin dosing for prevention of preeclampsia, focusing on dose-response relationships, timing of initiation, and phenotype-specific prophylaxis.Recent findings: Recent trials and meta-analyses have produced conflicting findings regarding whether higher-dose aspirin (100-162 mg daily) provides greater protection against preeclampsia than conventional 75-81 mg regimens. Benefit appears greatest in… Continue reading Toward Precision Aspirin Prophylaxis: Optimal Aspirin Dosing For Prevention of Preeclampsia
Oxygen cost of breathing and its association with dyspnea in older patients with heart failure with preserved ejection fraction and obesity
Introduction: Obesity is associated with an increased oxygen (O2) cost of breathing, which could contribute to dyspnea on exertion (DOE) and exercise intolerance. Many patients with heart failure with preserved ejection fraction (HFpEF) also have obesity, but whether an elevated O2 cost of breathing contributes to DOE and exercise intolerance in these patients is unclear.… Continue reading Oxygen cost of breathing and its association with dyspnea in older patients with heart failure with preserved ejection fraction and obesity
Colorectal cancer incidence and mortality by age group, colon location, and histology in Canada
Background: Colorectal cancer (CRC) incidence is increasing among younger individuals in many countries. We examined CRC incidence and mortality by age group, site, and histology in Canada.Methods: Data from the Canadian Cancer Registry and the Canadian Vital Statistics Death Database were used to determine CRC incidence from 1992 to 2019 and mortality from 1974 to… Continue reading Colorectal cancer incidence and mortality by age group, colon location, and histology in Canada
Post-Marketing Safety Signals of Microbiota-Based Live Biotherapeutic Products for Recurrent Clostridioides difficile Infection: A FAERS Pharmacovigilance Study
Background: REBYOTA and VOWST are the first FDA-approved live biotherapeutic products (LBPs) for recurrent Clostridioides difficile infection (rCDI). Prior FDA safety alerts (2019-2020) regarding invasive infections from investigational fecal microbiota transplantation underscore the need for post-marketing surveillance of these novel products.Aims: To characterize the real-world safety profiles of REBYOTA and VOWST using the FDA Adverse… Continue reading Post-Marketing Safety Signals of Microbiota-Based Live Biotherapeutic Products for Recurrent Clostridioides difficile Infection: A FAERS Pharmacovigilance Study
Validity and reliability of the Turkish version of the early symptom measurement of post-stroke depression short form (ESMPSD-SF)
The present methodological study was conducted to adapt the Early Symptom Measurement of Post-Stroke Depression developed by Li et al.1 into Turkish and to examine its validity and reliability. This study was conducted between September and December 2025 with a final sample of 120 patients diagnosed with stroke. Data were collected using a Personal Information… Continue reading Validity and reliability of the Turkish version of the early symptom measurement of post-stroke depression short form (ESMPSD-SF)
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