Buongiorno! My name is Aldo and I am an Internal Medicine Doctor. This is my Medical News Blog and I'm sure you'll find it useful and informative. All the articles can be searched by Category, Tag or Text. Just click on a post or on the Search link above.
Association of pre-endoscopic fresh frozen plasma transfusion with clinical outcomes in patients with acute upper gastrointestinal bleeding and mild coagulopathy: a two-center retrospective cohort study
The clinical benefit of fresh frozen plasma ( #FFP ) transfusion prior to endoscopy in patients with acute upper gastrointestinal bleeding (AUGIB) and mild coagulopathy remains uncertain. We evaluated the association between pre-endoscopic FFP transfusion and clinical outcomes in patients with AUGIB and an international normalized ratio (INR) of 1.5-2.5. We conducted a retrospective two-center… Continue reading Association of pre-endoscopic fresh frozen plasma transfusion with clinical outcomes in patients with acute upper gastrointestinal bleeding and mild coagulopathy: a two-center retrospective cohort study
Effectiveness of Non-Pharmacological Interventions for Hormone Therapy-Induced #Hand #Arthralgia in Breast Cancer Patients: A Systematic Review
BackgroundAromatase inhibitor-induced arthralgia (AIA) is a frequent adverse effect of endocrine therapy in breast cancer survivors, often leading to treatment modification or discontinuation. Non-pharmacological interventions have been proposed to manage AIA, but evidence remains fragmented.ObjectiveTo synthesize recent randomized controlled trials (RCTs) evaluating the efficacy of non-pharmacological interventions for AIA.MethodsA systematic search of PubMed, Scopus, and… Continue reading Effectiveness of Non-Pharmacological Interventions for Hormone Therapy-Induced #Hand #Arthralgia in Breast Cancer Patients: A Systematic Review
Real-time change in dynamic cerebral autoregulation after acupuncture at GB34 (Yanglingquan): a self-controlled study
Background: Few interventions have been proven to improve dynamic cerebral autoregulation (dCA). #GB34 is a common acupoint for motor function treatment in the clinic. However, the effects of acupuncture on dCA have never been reported and whether acupuncture at GB34 can improve dCA is unknown.Methods: A self-controlled interventional study was conducted. Each participant randomly received… Continue reading Real-time change in dynamic cerebral autoregulation after acupuncture at GB34 (Yanglingquan): a self-controlled study
Predicting adverse outcomes in dilated cardiomyopathy using 3D echocardiography: penalised Cox regression versus machine learning
Background: Risk prediction in dilated cardiomyopathy ( #DCM ) remains suboptimal, and there is uncertainty about how newer machine-learning (ML) methods compare with conventional regression for clinically useful prognostic modelling. Advanced three-dimensional (3D) echocardiographic measures, particularly of right ventricular function, may improve model performance when combined with routinely collected clinical data. We aimed to compare… Continue reading Predicting adverse outcomes in dilated cardiomyopathy using 3D echocardiography: penalised Cox regression versus machine learning
#Hepatitis E Infection in Patients With Inflammatory Bowel Diseases: A Systematic Review and Meta-Analysis
Opportunistic infections are increasingly recognised in patients with inflammatory bowel disease ( #IBD ), particularly among those receiving immunosuppressive therapy. Hepatitis E virus ( #HEV ) is a leading cause of acute viral hepatitis worldwide, yet its relevance in IBD remains insufficiently clarified. This systematic review and meta-analysis aimed to explore the association between HEV… Continue reading #Hepatitis E Infection in Patients With Inflammatory Bowel Diseases: A Systematic Review and Meta-Analysis
Female Underweight/Undernutrition Syndrome (FUS): An Emerging Health Concept in Premenopausal Women – Secondary Publication (English Translation of the Japanese Statement)
In Japan, approximately 20% of women in their twenties are #underweight (BMI < 18.5 kg/m2), representing one of the highest prevalences among developed nations. Underweight and undernutrition are associated with decreased bone mass, menstrual abnormalities, impaired glucose tolerance, sarcopenia-like changes, and systemic symptoms including depression and fatigue, significantly impacting health from young adulthood through the… Continue reading Female Underweight/Undernutrition Syndrome (FUS): An Emerging Health Concept in Premenopausal Women – Secondary Publication (English Translation of the Japanese Statement)
Electroacupuncture at Baliao Points Alleviates Ulcerative Colitis via α7nAChR-Mediated Macrophage Polarization and Gut Microbiota Modulation
Ulcerative colitis ( #UC ) is a chronic inflammatory disorder characterized by a significant unmet clinical need for more effective and tolerable therapies. This study explores the therapeutic potential and underlying mechanisms of electroacupuncture (EA) at the Baliao acupoints in a dextran sulfate sodium (DSS)-induced UC rat model. EA treatment significantly alleviated colitis symptoms, restored… Continue reading Electroacupuncture at Baliao Points Alleviates Ulcerative Colitis via α7nAChR-Mediated Macrophage Polarization and Gut Microbiota Modulation
A Qualitative Study Exploring Diabetes Prevention Intervention Needs and Ideas Among Young Adults at High Risk for Diabetes
ObjectiveTo explore perspectives of #young adults with #prediabetes and high burden of social needs about their intervention needs and ideas for solutions to enable behavior change.DesignQualitative study with semistructured interviews.SettingOne safety-net hospital and 1 academic medical center in a US city.ParticipantsTwenty-four publicly-insured adults aged 18–26 years with prediabetes (63% female, 71% Latino/a/x, 29% Black, 61%… Continue reading A Qualitative Study Exploring Diabetes Prevention Intervention Needs and Ideas Among Young Adults at High Risk for Diabetes
Segmental Electroacupuncture for Uterine Fibroids: A Case Report
Uterine #myomas, benign genital tract tumors, commonly lead to troublesome symptoms in females of reproductive age. Despite various surgical and hormonal treatments available for myomas, their possible side effects warrant the exploration of complementary medicine for myoma management. Segmental #electroacupuncture on acupoints located on myotomes with the same innervation as the uterus was performed for… Continue reading Segmental Electroacupuncture for Uterine Fibroids: A Case Report
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