Buongiorno! My name is Aldo and I am an Internal Medicine Doctor. This is my Medical News Blog and I'm sure you'll find it useful and informative. All the articles can be searched by Category, Tag or Text. Just click on a post or on the Search link above.
Immunological Basis of Chronic Spontaneous Urticaria: Immunoglobulin E and Beyond
Chronic spontaneous #urticaria (CSU) is associated with a substantial disease burden due to its prolonged course and significant impairment of quality of life. The diagnostic process for #CSU involves confirming the diagnosis itself and identifying disease phenotypes or endotypes, cofactors, and comorbid conditions, which may affect disease activity and severity. Immunoglobulin E (IgE) and non-IgE-mediated… Continue reading Immunological Basis of Chronic Spontaneous Urticaria: Immunoglobulin E and Beyond
Exploring White Matter Microstructural Abnormalities Using MRI in Women With Premenstrual Dysphoric Disorder via Brain Connectome
Background: The neurostructural underpinnings of #premenstrual dysphoric disorder (PMDD), particularly integrated white matter and network alteration, remain unclear.Purpose: To identify a core structural network in PMDD by integrating multiple diffusion tensor imaging (DTI)-derived metrics and to develop a predictive model.Study type: Prospective case-control study.Subjects: Forty-two PMDD patients (age: 23.86 ± 1.32 years), diagnosed according to… Continue reading Exploring White Matter Microstructural Abnormalities Using MRI in Women With Premenstrual Dysphoric Disorder via Brain Connectome
Evaluation of Rabeprazole for Gastrointestinal Protection in Acute Coronary Syndrome Patients Treated with Aspirin and Ticagrelor: A Pilot Study
Purpose: Patients with acute coronary syndrome (#ACS ) on ticagrelor-based dual antiplatelet therapy (#DAPT ) have an increased risk of gastrointestinal (GI) bleeding. However, evidence supporting the protective role of proton pump inhibitors against DAPT-induced gastric mucosal injury remains limited.Materials and methods: This was a single-center, prospective, open-label, observational trial enrolling patients with ACS who… Continue reading Evaluation of Rabeprazole for Gastrointestinal Protection in Acute Coronary Syndrome Patients Treated with Aspirin and Ticagrelor: A Pilot Study
Electroacupuncture for slow flow/no-reflow in patients with acute myocardial infarction undergoing percutaneous coronary intervention: a pilot randomized controlled trial
Background: Slow flow/no-reflow (SF-NR) complicates up to 44% of percutaneous #coronary interventions ( #PCI) for acute myocardial infarction (#AMI), worsening prognosis. Electroacupuncture (EA) may mitigate SF-NR, but clinical evidence is limited.Objective: This trial was designed to assess the feasibility and effectiveness of intraoperative EA in reducing SF-NR during PCI for AMI patients.Design setting and participants… Continue reading Electroacupuncture for slow flow/no-reflow in patients with acute myocardial infarction undergoing percutaneous coronary intervention: a pilot randomized controlled trial
Development and validation of a deep learning model to predict visual and anatomical prognosis of anti-VEGF therapy for neovascular age-related macular degeneration (KongMing Study): a prospective, nationwide, multicentre study
Background: The financial burden and the uncertain response of the anti-vascular endothelial growth factor (anti-VEGF) treatment often cause hesitation among patients with neovascular age-related #macular degeneration (nAMD), highlighting the need for a reliable method to predict treatment outcomes. We aimed to develop and validate a deep learning model that can predict the visual and anatomical… Continue reading Development and validation of a deep learning model to predict visual and anatomical prognosis of anti-VEGF therapy for neovascular age-related macular degeneration (KongMing Study): a prospective, nationwide, multicentre study
Clinical Outcome Associated With Beta-Lactam Allergy Labels in Hospitalized Patients in Belgium
Background: In the United States, beta-lactam #allergy labels (BLAL) are documented in 9%-16% of hospitalized patients and associated with worse clinical outcomes such as increased mortality, length of hospital stay (LOS), intensive care unit (ICU) admission, and use of alternative antibiotics, providing an incentive for broad delabeling protocols. In Europe, BLAL prevalences are lower (0.6%-5%)… Continue reading Clinical Outcome Associated With Beta-Lactam Allergy Labels in Hospitalized Patients in Belgium
Clinical Observation of Music Therapy Combined with Acupoint Application for the Treatment of Functional Constipation
This study assessed the clinical efficacy of combining five-tone therapy with acupoint application, guided by the #TCM midnight-noon ebb-flow theory, for treating functional #constipation (FC). A total of 103 FC patients were divided into a study group (n=52) and a control group (n=51). The control group received oral polyethylene glycol with routine diet and exercise.… Continue reading Clinical Observation of Music Therapy Combined with Acupoint Application for the Treatment of Functional Constipation
Measurement of blood pressure in European Society of Hypertension Excellence Centres: A survey by the Young Investigators Group of the European Society of Hypertension
Background: Office blood #pressure (BP) measurement is the cornerstone of #hypertension diagnosis and risk stratification. Inaccurate BP readings can lead to significant misclassification, often overestimating BP and prompting unnecessary lifelong treatment. The Young Investigators Group of the European Society of Hypertension (YIG-ESH) conducted a structured, comprehensive survey among ESH Excellence Centres with the primary objective… Continue reading Measurement of blood pressure in European Society of Hypertension Excellence Centres: A survey by the Young Investigators Group of the European Society of Hypertension
Immersive Virtual Reality Training to Improve Novice Physicians’ Emergency Response Skills: Randomized Controlled Trial
Background:Simulation-based training is essential for preparing medical interns to manage high-stakes emergencies. Although virtual reality (VR)-based simulation has been rapidly integrated into medical education, there remains limited evidence directly assessing its effectiveness relative to established high-fidelity simulation (HFS) methodologies.Objective:This study aimed to assess the perceived educational effectiveness of #VR and HFS in enhancing novice physicians’… Continue reading Immersive Virtual Reality Training to Improve Novice Physicians’ Emergency Response Skills: Randomized Controlled Trial
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