Prolonged Moderate-Intensity Exercise Does Not Increase Muscle Injury Markers in Symptomatic or Asymptomatic Statin Users

BackgroundStatin use may exacerbate exercise-induced skeletal muscle injury caused by reduced coenzyme Q10 (CoQ10) levels, which are postulated to produce mitochondrial dysfunction.ObjectivesWe determined the effect of prolonged moderate-intensity exercise on markers of muscle injury in statin users with and without statin-associated muscle symptoms. We also examined the association between leukocyte CoQ10 levels and muscle markers, …

Continue reading Prolonged Moderate-Intensity Exercise Does Not Increase Muscle Injury Markers in Symptomatic or Asymptomatic Statin Users

Physical exercise for people with Parkinson’s disease: a systematic review and network meta‐analysis

Physical exercise is effective in managing Parkinson's disease (PD), but the relative benefit of different exercise types remains unclear.ObjectivesTo compare the effects of different types of physical exercise in adults with PD on the severity of motor signs, quality of life (QoL), and the occurrence of adverse events, and to generate a clinically meaningful treatment …

Continue reading Physical exercise for people with Parkinson’s disease: a systematic review and network meta‐analysis

Are the different cut-off points for sitting time associated with excess weight in adults? A population based study in Latin America

Excess weight is increasing worldwide, and in Latin America more than half of the population is excess weight. One of the reasons for this increase has been excessive sitting time. Still, it remains to be seen whether there is an excessive amount of that time in Latin American adults. This study aimed to associate different …

Continue reading Are the different cut-off points for sitting time associated with excess weight in adults? A population based study in Latin America

Morning Exercise Reduces Abdominal Fat and Blood Pressure in Women; Evening Exercise Increases Muscular Performance in Women and Lowers Blood Pressure in Men

The ideal exercise time of day (ETOD) remains elusive regarding simultaneous effects on health and performance outcomes, especially in women.Purpose: Given known sex differences in response to exercise training, this study quantified health and performance outcomes in separate cohorts of women and men adhering to different ETOD.Methods: Thirty exercise-trained women (BMI = 24 ± 3 …

Continue reading Morning Exercise Reduces Abdominal Fat and Blood Pressure in Women; Evening Exercise Increases Muscular Performance in Women and Lowers Blood Pressure in Men

Effectiveness of physical activity interventions for improving depression, anxiety and distress: an overview of systematic reviews

Objective To synthesise the evidence on the effects of physical activity on symptoms of depression, anxiety and psychological distress in adult populations.Design Umbrella review.Data sources Twelve electronic databases were searched for eligible studies published from inception to 1 January 2022.Eligibility criteria for selecting studies Systematic reviews with meta-analyses of randomised controlled trials designed to increase …

Continue reading Effectiveness of physical activity interventions for improving depression, anxiety and distress: an overview of systematic reviews