Background: Studies show variable results on health outcomes of isolated diastolic hypertension (IDH); however, data are scarce on its association with early kidney injury.Methods: We analyzed the Korea National Health and Nutrition Examination Survey data (2011-2014 and 2019-2024) in adults ≥19 years. After excluding those taking antihypertensive medication or with established kidney disease, participants were… Continue reading Association of isolated systolic and diastolic hypertension with moderately increased albuminuria: the Korea National Health and Nutrition Examination Survey
Tag: Hypertension
Efficacy and safety of lorundrostat in uncontrolled hypertension: a systematic review, meta-analysis, and meta-regression
Background: Uncontrolled hypertension (UH), a severe form of hypertension, persists despite the use of three or more antihypertensive medications. Its growing prevalence, particularly in patients with comorbidities, necessitates novel therapeutic options. Lorundrostat, a selective aldosterone synthase inhibitor, presents a promising mechanism of action by directly reducing aldosterone synthesis while sparing cortisol production, potentially offering an… Continue reading Efficacy and safety of lorundrostat in uncontrolled hypertension: a systematic review, meta-analysis, and meta-regression
Blood Pressure Phenotypes and Cardio-Kidney Outcomes: Findings From UK Biobank Data
Background: Hypertension is a leading cause of cardio-kidney outcomes (CKO). However, distinct blood pressure (BP) phenotypes and their effect on CKO remain underexplored. This study aimed to evaluate the independent contributions of BP phenotypes to CKO.Methods: This prospective, population-based study included UK Biobank participants enrolled between 2006 and 2010 with baseline systolic BP ≥90 mm… Continue reading Blood Pressure Phenotypes and Cardio-Kidney Outcomes: Findings From UK Biobank Data
Degree of urbanization and the prevalence of hypertension and diabetes mellitus in South Korea (Insight from Gyeonggi Province): A cross-sectional analysis with temporal trends, 2008-2023
Background: Despite South Korea's achievement of Universal Health Coverage (UHC), regional health inequities persist as a significant public health challenge. Traditional urban-rural classifications often fail to capture the nuanced spatial dynamics of modern settlement patterns. This study aimed to evaluate the prevalence of hypertension (HTN) and diabetes mellitus (DM) across the urbanization gradient-Cities, Urbanized, and… Continue reading Degree of urbanization and the prevalence of hypertension and diabetes mellitus in South Korea (Insight from Gyeonggi Province): A cross-sectional analysis with temporal trends, 2008-2023
Effect of relative handgrip strength and back muscle strength on the incidence of hypertension: 18-year follow-up in a population-based cohort study
Substantial evidence supports an association between physical #exercises and #hypertension. However, the role of muscle #strength, such as hand grip strength (HGS) and back muscle strength (BMS), remains unclear in this relationship. This study investigated whether low BMS and HGS accelerated incident hypertension in a population-based prospective study. A total 3,038 non-hypertensive subjects aged 40-69… Continue reading Effect of relative handgrip strength and back muscle strength on the incidence of hypertension: 18-year follow-up in a population-based cohort study
Blood Pressure Control and Mortality Among US Veterans
Background: Intensive blood #pressure (#BP) control reduces mortality and cardiovascular disease in clinical trials. However, real-world BP measurements often differ from standardized protocols. We evaluated the impact of real-world systolic BP on mortality among US Veterans.Methods: We conducted a retrospective cohort study of Veterans with hypertension, defined by diagnostic codes, antihypertensive prescriptions, or ≥2 office… Continue reading Blood Pressure Control and Mortality Among US Veterans
Measurement of blood pressure in European Society of Hypertension Excellence Centres: A survey by the Young Investigators Group of the European Society of Hypertension
Background: Office blood #pressure (BP) measurement is the cornerstone of #hypertension diagnosis and risk stratification. Inaccurate BP readings can lead to significant misclassification, often overestimating BP and prompting unnecessary lifelong treatment. The Young Investigators Group of the European Society of Hypertension (YIG-ESH) conducted a structured, comprehensive survey among ESH Excellence Centres with the primary objective… Continue reading Measurement of blood pressure in European Society of Hypertension Excellence Centres: A survey by the Young Investigators Group of the European Society of Hypertension
The comparative effects of S-amlodipine versus racemic amlodipine on long-term cardiovascular outcomes in subjects with hypertension: a nationwide population-based cohort study
Although S- #amlodipine is known to have similar effects in lowering blood #pressure and fewer side effects compared to amlodipine (= mixture of S- and R-amlodipine), there are no available data on its impact on long-term cardiovascular prognosis. This retrospective cohort study analyzed claims data from Korean subjects with hypertension treated with either S-amlodipine or… Continue reading The comparative effects of S-amlodipine versus racemic amlodipine on long-term cardiovascular outcomes in subjects with hypertension: a nationwide population-based cohort study
The Overlooked Driver of #Hypertension: Mental #Stress at the Crossroad of Cardiology and Psychiatry
AbstractPurpose of ReviewMental stress has long been overlooked in the development of hypertension. We aim to provide new insights for clinicians in managing this condition.This review aims to summarize the epidemiological characteristics, complex mechanisms, diagnostic methods, as well as both non-pharmacological and pharmacological treatment strategies for mental stress-induced hypertension.Recent FindingsMany hypertensive patients continue to experience… Continue reading The Overlooked Driver of #Hypertension: Mental #Stress at the Crossroad of Cardiology and Psychiatry
