Effects of oral #semaglutide on energy intake, #food preference, #appetite, control of eating and body #weight in subjects with type 2 #diabetes

Aims To evaluate the effect of oral semaglutide on energy intake and appetite in subjects with type 2 diabetes (T2D). Materials and methods In this randomised, double‐blind, placebo‐controlled, two‐period cross‐over trial, 15 subjects with T2D received 12 weeks’ treatment with once‐daily oral semaglutide (4‐week dose‐escalation from 3 to 7 to 14 mg) followed by placebo, or vice versa. Energy intake was measured during an ad … Continue reading Effects of oral #semaglutide on energy intake, #food preference, #appetite, control of eating and body #weight in subjects with type 2 #diabetes

#Smoking Cessation, #Weight Change, #Diabetes, and #Hypertension in Korean Adult

This study investigates the association of smoking cessation and postcessation weight gain with the development of type 2 diabetes mellitus and hypertension. Methods A total of 96,524 individuals without diabetes mellitus and hypertension aged ≥20 years between 2006 and 2008 were included, with follow-up until December 31, 2015. Smoking status and weight changes were monitored for 2 years. Hazard ratios and 95% CIs were calculated … Continue reading #Smoking Cessation, #Weight Change, #Diabetes, and #Hypertension in Korean Adult

A Time Frame for Testing Negative for SARS- #COV2 in People with #Obesity

Objective: Obesity is a major risk factor for becoming seriously ill with the 2019 novel coronavirus (COVID-19). One difficulty faced by clinicians and by patients is the unknown time frame of hospitalization until discharge of symptomatic patients. Methods: We followed 34 patients with laboratory-confirmed COVID-19 infection who recovered fromthe infection. All diagnoses were given using semi-quantitative RT-PCR on nasopharyngeal swabs. Envelope protein gene (E), RNA-dependent … Continue reading A Time Frame for Testing Negative for SARS- #COV2 in People with #Obesity

#BMI and All‐Cause #Mortality in a Population‐Based Cohort in Rural South Africa

..The cohort consisted of 9,728 individuals. In adjusted models, those with BMI of 25.0 to 29.9 kg/m2 or 30.0 to 34.9 kg/m2 had a lower hazard of death (adjusted hazard ratio: 0.80; 95% CI: 0.69‐0.92 and adjusted hazard ratio: 0.75; 95% CI: 0.60‐0.93, respectively) compared with those with BMI of 18.5 to 24.9 kg/m2. Conclusions Individuals in South Africa who meet clinically defined criteria for … Continue reading #BMI and All‐Cause #Mortality in a Population‐Based Cohort in Rural South Africa

#Life Expectancy after #Bariatric Surgery in the Swedish Obese Subjects Study

Obesity shortens life expectancy. Bariatric surgery is known to reduce the long-term relative risk of death, but its effect on life expectancy is unclear.. ..In total, 2007 and 2040 patients were included in the surgery group and the control group, respectively, and 1135 participants were included in the reference cohort. At the time of the analysis (December 31, 2018), the median duration of follow-up for … Continue reading #Life Expectancy after #Bariatric Surgery in the Swedish Obese Subjects Study

Genetic and Environmental Influences on Blood #Pressure and Body #Mass Index in the National Academy of Sciences–National Research Council World War II Veteran Twin Registry

Blood pressure (BP) and obesity phenotypes may covary due to shared genetic or environmental factors or both. Furthermore, it is possible that the heritability of BP differs according to obesity status—a form of G×E interaction. This hypothesis has never been tested in White twins. The present study included 15 924 White male twin pairs aged between 15 and 33 years from the National Academy of Sciences–National … Continue reading Genetic and Environmental Influences on Blood #Pressure and Body #Mass Index in the National Academy of Sciences–National Research Council World War II Veteran Twin Registry

Prevalence and Prognostic Significance of #Malnutrition in Patients With Acute #Coronary Syndrome

Malnutrition is associated with poor prognosis in a wide range of illnesses. However, its prognostic impact in patients with acute coronary syndrome (ACS) is not well known.. ..In this study, the Controlling Nutritional Status (CONUT) score, the Nutritional Risk Index (NRI), and the Prognostic Nutritional Index (PNI) was applied to 5,062 consecutive patients with ACS. The relationships between malnutrition risk and all-cause mortality and major … Continue reading Prevalence and Prognostic Significance of #Malnutrition in Patients With Acute #Coronary Syndrome

Effects of Time-Restricted Eating on #Weight Loss and Other Metabolic Parameters in Women and Men With Overweight and #Obesity

.. Participants were randomized such that the consistent meal timing (CMT) group was instructed to eat 3 structured meals per day, and the time-restricted eating (TRE) group was instructed to eat ad libitum from 12:00 pm until 8:00 pm and completely abstain from caloric intake from 8:00 pm until 12:00 pm the following day. Design, Setting, and Participants This 12-week randomized clinical trial including men … Continue reading Effects of Time-Restricted Eating on #Weight Loss and Other Metabolic Parameters in Women and Men With Overweight and #Obesity

Trends in #Adiposity and #Food Insecurity Among US Adults

..Food insecurity is a core indicator of nutritional status and “exists whenever the availability of nutritionally adequate and safe foods or the ability to acquire acceptable foods in socially acceptable ways is limited or uncertain.” ..Main Outcomes and Measures The primary outcome was food insecurity. Data on BMI (calculated as weight in kilograms divided by height in meters squared) were categorized as follows: normal weight … Continue reading Trends in #Adiposity and #Food Insecurity Among US Adults

Associations of #BMI and Serum #Urate with Developing #Dementia: A Prospective Cohort Study

Recent studies suggested that higher BMI and serum urate levels were associated with lower risk of developing dementia. However, these reverse relationships remain controversial, and whether serum urate and BMI confound each other is not well established.. ..During a median of 8.1 years of follow-up, a total of 2138 participants developed dementia. People who were underweight had an increased risk of dementia (hazard ratio [HR] … Continue reading Associations of #BMI and Serum #Urate with Developing #Dementia: A Prospective Cohort Study

#Obesity Has a Stronger Relationship with Colorectal #Cancer in Postmenopausal Women Than Premenopausal Women

Background: To examine the relationship between obesity measured by waist circumference (WC) and body mass index (BMI) and the incidence of colorectal cancer (CRC) in premenopausal and postmenopausal women. Methods: A total of 1,418,180 premenopausal and 4,854,187 postmenopausal women without cancer at baseline and aged over 40 were identified using the Korean National Health Insurance System Cohort during 2009-2014. The hazard ratio (HR) for CRC … Continue reading #Obesity Has a Stronger Relationship with Colorectal #Cancer in Postmenopausal Women Than Premenopausal Women