Association between #obesity with pattern and length of #menstrual cycle: The role of metabolic and hormonal markers

To evaluate in a sample of Chilean adult women, the association between adiposity markers with pattern and length of the menstrual cycle, assessing the influence of metabolic markers and hormones in this relationship. Study design We conducted a cross-sectional study involving 401 premenopausal women belonging to the DERCAM study (Determinants of Breast Cancer Risk) from Santiago, Chile. The menstrual cycle pattern was defined as regular … Continue reading Association between #obesity with pattern and length of #menstrual cycle: The role of metabolic and hormonal markers

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Self- Monitoring via Digital Health in #Weight Loss Interventions: A Systematic Review Among Adults with Overweight or #Obesity

Objective: Self- monitoring is a core component of behavioral obesity treatment, but it is unknown how digital health has been used for self- monitoring, what engagement rates are achieved in these interven-tions, and how self- monitoring and weight loss are related. Methods: This systematic review examined digital self- monitoring in behavioral weight loss interventions among adults with overweight or obesity. Six databases (PubMed, Embase, Scopus, … Continue reading Self- Monitoring via Digital Health in #Weight Loss Interventions: A Systematic Review Among Adults with Overweight or #Obesity

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Once-Weekly #Semaglutide in Adults with Overweight or #Obesity

Obesity is a global health challenge with few pharmacologic options. Whether adults with obesity can achieve weight loss with once-weekly semaglutide at a dose of 2.4 mg as an adjunct to lifestyle intervention has not been confirmed. METHODS In this double-blind trial, we enrolled 1961 adults with a body-mass index (the weight in kilograms divided by the square of the height in meters) of 30 … Continue reading Once-Weekly #Semaglutide in Adults with Overweight or #Obesity

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Effects of two personalized #dietary strategies during a 2‐year intervention in subjects with nonalcoholic #fatty #liver disease: a randomized trial

Background and objectives Nonalcoholic fatty liver disease (NAFLD) management is focused on lifestyle modifications, but long‐term maintenance is a challenge for many individuals. This study aimed to evaluate the long‐term effects of two personalized energy‐restricted dietary strategies on weight loss, metabolic and hepatic outcomes in overweight/obese subjects with NAFLD. Methods Ninety‐eight subjects from the Fatty Liver in Obesity (FLiO) study (NCT03183193) were randomly assigned to … Continue reading Effects of two personalized #dietary strategies during a 2‐year intervention in subjects with nonalcoholic #fatty #liver disease: a randomized trial

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#Adipose saturation reduces #lipotoxic systemic inflammation and explains the #obesity paradox

Obesity sometimes seems protective in disease. This obesity paradox is predominantly described in reports from the Western Hemisphere during acute illnesses. Since adipose triglyceride composition corresponds to long-term dietary patterns, we performed a meta-analysis modeling the effect of obesity on severity of acute pancreatitis, in the context of dietary patterns of the countries from which the studies originated. Increased severity was noted in leaner populations … Continue reading #Adipose saturation reduces #lipotoxic systemic inflammation and explains the #obesity paradox

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Childhood Daily #Energy Expenditure Does Not Decrease with Market Integration and Is Not Related to #Adiposity in Amazonia

Childhood overweight and obesity (OW/OB) is increasingly centered in low- and middle-income countries (LMICs) as rural populations experience market integration and lifeway change. Most explanatory studies have relied on imprecise estimates of children’s energy expenditure, restricting understanding of the relative effects of changes in diet and energy expenditure on the development of OW/OB in transitioning contexts.. ..Cross-sectional data were collected from “rural” (n = 43) … Continue reading Childhood Daily #Energy Expenditure Does Not Decrease with Market Integration and Is Not Related to #Adiposity in Amazonia

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Organ-specific, multimodal, wireless optoelectronics for high-throughput phenotyping of peripheral neural pathways

The vagus nerve supports diverse autonomic functions and behaviors important for health and survival. To understand how specific components of the vagus contribute to behaviors and long-term physiological effects, it is critical to modulate their activity with anatomical specificity in awake, freely behaving conditions using reliable methods. Here, we introduce an organ-specific scalable, multimodal, wireless optoelectronic device for precise and chronic optogenetic manipulations in vivo. … Continue reading Organ-specific, multimodal, wireless optoelectronics for high-throughput phenotyping of peripheral neural pathways

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U.S. #Diet Guidelines Sidestep Scientific Advice to Cut #Sugar and #Alcohol

..Evidence suggests that added sugars, particularly those in sweetened beverages, may contribute to obesity and weight gain, which are linked to higher rates of chronic health conditions like heart disease and Type 2 diabetes, the scientific panel noted. More than two-thirds of American adults are overweight or obese; obesity, diabetes and other related conditions also increase the risk of developing severe Covid-19 illness. The scientific … Continue reading U.S. #Diet Guidelines Sidestep Scientific Advice to Cut #Sugar and #Alcohol

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#Avocado Consumption Alters Gastrointestinal #Bacteria Abundance and Microbial Metabolite Concentrations among Adults with Overweight or #Obesity: A Randomized Controlled Trial

Avocados are rich in dietary fiber and monounsaturated fatty acids (MUFAs), nutrients that have been independently connected to metabolic health benefits and the gastrointestinal microbiota. Objectives We aimed to evaluate the impact of avocado consumption on the gastrointestinal microbiota and microbial metabolites, secondary outcomes of the Persea americana for Total Health (PATH) study, and conduct exploratory analyses to assess relations between the fecal microbiota, fecal … Continue reading #Avocado Consumption Alters Gastrointestinal #Bacteria Abundance and Microbial Metabolite Concentrations among Adults with Overweight or #Obesity: A Randomized Controlled Trial

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#Cooking as a Health Behavior: Examining the Role of Cooking Classes in a #Weight Loss Intervention

Americans are cooking fewer meals at home and eating more convenience foods prepared elsewhere. Cooking at home is associated with higher quality diets, while a reduction in cooking may be associated with increases in obesity and risk factors for chronic disease. The aims of this study were to examine cooking as an intervention for weight control in overweight and obese adults, and whether such an … Continue reading #Cooking as a Health Behavior: Examining the Role of Cooking Classes in a #Weight Loss Intervention

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#Older age does not influence the success of #weight loss through the implementation of lifestyle modification

Age is sometimes a barrier for acceptance of patients into a hospital‐based obesity service. Our aim was to explore the effect of age on the ability to lose weight through lifestyle interventions, implemented within a hospital‐based obesity service.. Primary outcome measures were percentage weight loss (%WL) and percentage reduction in body mass index (%rBMI) following implemented lifestyle interventions. Data were stratified according to patient age … Continue reading #Older age does not influence the success of #weight loss through the implementation of lifestyle modification

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Effects of oral #semaglutide on energy intake, #food preference, #appetite, control of eating and body #weight in subjects with type 2 #diabetes

Aims To evaluate the effect of oral semaglutide on energy intake and appetite in subjects with type 2 diabetes (T2D). Materials and methods In this randomised, double‐blind, placebo‐controlled, two‐period cross‐over trial, 15 subjects with T2D received 12 weeks’ treatment with once‐daily oral semaglutide (4‐week dose‐escalation from 3 to 7 to 14 mg) followed by placebo, or vice versa. Energy intake was measured during an ad … Continue reading Effects of oral #semaglutide on energy intake, #food preference, #appetite, control of eating and body #weight in subjects with type 2 #diabetes

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