Implications of Abnormal Exercise Electrocardiography With Normal Stress Echocardiography

..After excluding submaximal tests and nondiagnostic ECG or stress imaging results, 15 077 patients (mean [SD] age, 52 [13] years; 6228 [41.3%] men) were classified by stress test results Death occurred in 425 patients with −ECG/−Echo (4.8%), 50 patients with +ECG/−Echo (5.9%), and 70 patients with +Echo (11.2%). Myocardial infarction occurred in 195 patients with −ECG/−Echo (2.2%), 31 patients with +ECG/−Echo (3.6%), and 59 patients with … Continue reading Implications of Abnormal Exercise Electrocardiography With Normal Stress Echocardiography

Abdominal #obesity and the risk of recurrent atherosclerotic cardiovascular disease after myocardial #infarction

..Univariate and multivariable-adjusted Cox regression models were used to calculate hazard ratios and 95% confidence intervals in quintiles of waist circumference as well as three categories of body mass index including normal weight, overweight and obesity. Results The majority of patients had abdominal obesity. During a median follow-up time of 3.8 years, 1232 men (7.3%) and 469 women (7.9%) experienced a recurrent atherosclerotic cardiovascular disease … Continue reading Abdominal #obesity and the risk of recurrent atherosclerotic cardiovascular disease after myocardial #infarction

Efficacy and Safety of Low-Dose #Colchicine after Myocardial #Infarction

We performed a randomized, double-blind trial involving patients recruited within 30 days after a myocardial infarction. The patients were randomly assigned to receive either low-dose colchicine (0.5 mg once daily) or placebo.. ..The primary end point occurred in 5.5% of the patients in the colchicine group, as compared with 7.1% of those in the placebo group (hazard ratio, 0.77; 95% confidence interval [CI], 0.61 to … Continue reading Efficacy and Safety of Low-Dose #Colchicine after Myocardial #Infarction

#Hemoglobin concentration and risk of arterial and venous #thrombosis in 1.5 million Swedish and Danish blood donors

..The risk of myocardial infarction and ischemic stroke increased with higher hemoglobin concentration in both men and women. The HRs for myocardial infarction and ischemic stroke in men with hemoglobin concentration ≥ 17.5 g/dL were 3.52 (95% confidence interval [CI], 2.85–4.36) and 2.36 (95% CI, 1.63–3.43), respectively, compared to the reference group. The corresponding HRs for women with hemoglobin concentration ≥ 16.0 g/dL were 3.22 (2.12–4.89) and 2.35 (1.37–4.02) for myocardial … Continue reading #Hemoglobin concentration and risk of arterial and venous #thrombosis in 1.5 million Swedish and Danish blood donors

Acute #Kidney Injury Among Older Patients Undergoing Coronary #Angiography for Acute Myocardial Infarction: The SILVER-AMI Study

..Comorbid diseases and aging-related conditions were both more common among individuals experiencing acute kidney injury. However, after multivariable adjustment, no aging-related conditions were retained. There were 11 risk factors in the final model; the strongest were heart failure on presentation (odds ratio [OR] 1.91; 95% confidence interval [CI], 1.41-2.59), body mass index [BMI] >30 (vs BMI 18-25: OR 1.75; 95% CI, 1.27-2.42), and nonwhite race … Continue reading Acute #Kidney Injury Among Older Patients Undergoing Coronary #Angiography for Acute Myocardial Infarction: The SILVER-AMI Study