Current guidelines published by the American Heart Association and the American College of Cardiology broadly recommend lifestyle approaches to prevent and treat elevated blood pressure and cholesterol. For patients with mildly or moderately elevated blood pressure and blood cholesterol, lifestyle-only approaches are the first line of therapy. The purpose of this scientific statement is to: … Continue reading #Physical Activity as a Critical Component of First-Line Treatment for Elevated Blood #Pressure or #Cholesterol: Who, What, and How?: A Scientific Statement From the American Heart Association
Tag: CVD
Having a family member with an alcohol use disorder (AUD) may negatively affect a person’s health. Our aim was to study the long-term risk of coronary heart disease (CHD) in parents who have an offspring with AUD. DesignCohort study. Cox regression models and co-sibling analyses. SettingSweden. ParticipantsFrom population registers, we selected all parent-offspring pairs in … Continue reading #Coronary heart disease in mothers and fathers of adult children with #alcohol use disorders
Obesity is associated with increased cardiovascular risk; however, the potential role of dysregulations in the adipose tissue (AT) metabolome is unknown. ObjectivesThe aim of this study was to explore the role of dysregulation in the AT metabolome on vascular redox signaling and cardiovascular outcomes. MethodsA screen was conducted for metabolites differentially secreted by thoracic AT … Continue reading #Fat-Secreted Ceramides Regulate Vascular Redox State and Influence Outcomes in Patients With #Cardiovascular Disease
Endovascular renal denervation reduces blood pressure in patients with mild-to-moderate hypertension, but its efficacy in patients with true resistant hypertension has not been shown. We aimed to assess the efficacy and safety of endovascular ultrasound renal denervation in patients with hypertension resistant to three or more antihypertensive medications. MethodsIn a randomised, international, multicentre, single-blind, sham-controlled … Continue reading Ultrasound renal #denervation for #hypertension resistant to a triple medication pill (RADIANCE-HTN TRIO): a randomised, multicentre, single-blind, sham-controlled trial
