Low #carbohydrate diet and all cause and cause-specific #mortality

Evidence is limited regarding the association between low-carbohydrate diet (LCD) score and mortality among Asians, a population that consumes a large amount of carbohydrates.. ..A U-shaped association was observed between LCD score and total mortality: the multivariable-adjusted hazard ratios (HRs) (95% CI) of total mortality for lowest through highest scores were 1.00, 0.95 (0.91, 1.01), 0.93 (0.88, 0.98), 0.93 (0.88, 0.98), and 1.01 (0.95, 1.07) … Continue reading Low #carbohydrate diet and all cause and cause-specific #mortality

Interventions to Improve #Statin Tolerance and Adherence in Patients at Risk for #Cardiovascular Disease

Strategies to improve patients’ tolerance of and adherence to statins may enhance the effectiveness of dyslipidemia treatment in those at risk for cardiovascular disease (CVD).. ..One SR, 1 RCT, and 4 cohort studies were included. The SR found that intensified patient care improved adherence and decreased levels of total serum cholesterol and low-density lipoprotein cholesterol (LDL-C) at 6 months or more of follow-up. Compared with … Continue reading Interventions to Improve #Statin Tolerance and Adherence in Patients at Risk for #Cardiovascular Disease

Association of Hepatic #Steatosis with Major Adverse Cardiovascular Events, Independent of #Coronary Artery Disease

Hepatic steatosis has been associated with increased risk of major adverse cardiovascular events (MACE) but it is not clear whether steatosis is independently associated with risk of MACE. We investigated whether steatosis is associated with risk of MACE independently of the presence and extent of baseline coronary artery disease, assessed by comprehensive contrast-enhanced computed tomography angiography (CTA).. ..Among the 959 subjects who had steatosis (25.5% … Continue reading Association of Hepatic #Steatosis with Major Adverse Cardiovascular Events, Independent of #Coronary Artery Disease

Association between #prediabetes and risk of all cause mortality and #cardiovascular disease: updated meta-analysis

To evaluate the associations between prediabetes and the risk of all cause mortality and incident cardiovascular disease in the general population and in patients with a history of atherosclerotic cardiovascular disease.. ..A total of 129 studies were included, involving 10 069 955 individuals for analysis. In the general population, prediabetes was associated with an increased risk of all cause mortality (relative risk 1.13, 95% confidence interval 1.10 … Continue reading Association between #prediabetes and risk of all cause mortality and #cardiovascular disease: updated meta-analysis

Association of Childhood #Psychosocial Environment With 30‐Year #Cardiovascular Disease Incidence and Mortality in Middle Age

Childhood adversity and trauma have been shown to be associated with poorer cardiovascular disease (CVD) outcomes in adulthood. However, longitudinal studies of this association are rare.. ..Participants (n=3646) completed the Childhood Family Environment (CFE) questionnaire at the year 15 (2000–2001) CARDIA examination and were grouped by high, moderate, or low relative CFE adversity scores.. ..Participants were 25.1±3.6 years old, 47% black, and 56% female at … Continue reading Association of Childhood #Psychosocial Environment With 30‐Year #Cardiovascular Disease Incidence and Mortality in Middle Age

#Olive Oil Consumption and Cardiovascular Risk in U.S. Adults

Olive oil intake has been associated with lower risk of cardiovascular disease (CVD) in Mediterranean populations, but little is known about these associations in the U.S population.. ..During 24 years of follow-up, this study documented 9,797 incident cases of CVD, including 6,034 CHD cases and 3,802 stroke cases. After adjusting for major diet and lifestyle factors, compared with nonconsumers, those with higher olive oil intake … Continue reading #Olive Oil Consumption and Cardiovascular Risk in U.S. Adults

Effect of Smartphone-Enabled #Health Monitoring Devices vs Regular Follow-up on Blood Pressure Control Among Patients After Myocardial #Infarction

..For patients randomized to regular care, 4 physical outpatient clinic visits were scheduled in the year following the initial event. In the intervention group, patients were given 4 smartphone-compatible devices (weight scale, BP monitor, rhythm monitor, and step counter). In addition, 2 in-person outpatient clinic visits were replaced by electronic visits ..In total, 200 patients (median age, 59.7 years [interquartile range, 52.9-65.6 years]; 156 men … Continue reading Effect of Smartphone-Enabled #Health Monitoring Devices vs Regular Follow-up on Blood Pressure Control Among Patients After Myocardial #Infarction

Short-Term Progression of Multiterritorial Subclinical #Atherosclerosis

..Imaging detected short-term (3-year) atherosclerosis progression in 41.5% of participants (26.4% by 2DVUS, 21.3% by 3DVUS, and 11.5% by CACS), particularly in peripheral territories examined by vascular ultrasound. New atherosclerosis onset accounted for approximately one-third of total progression, also more frequently by 2DVUS and 3DVUS (29.1% and 16.6%, respectively), than by CACS (2.9%). Participants with baseline disease by all 3 modalities (n = 432) also … Continue reading Short-Term Progression of Multiterritorial Subclinical #Atherosclerosis

Cardiac #Autoimmunity Is Associated With Subclinical Myocardial Dysfunction in Patients With Type 1 #Diabetes Mellitus

The existence of a diabetic cardiomyopathy has been postulated to explain the increased risk of heart failure (HF) in patients with diabetes mellitus; however, whether mechanisms specific to type 1 diabetes mellitus (T1DM) affect the myocardium is unclear. We have recently shown that poor glycemic control in patients with T1DM followed in the DCCT (Diabetes Control and Complications Trial), but not in patients with type … Continue reading Cardiac #Autoimmunity Is Associated With Subclinical Myocardial Dysfunction in Patients With Type 1 #Diabetes Mellitus

Potential Effects of #Coronaviruses on the #Cardiovascular System

Coronavirus disease 2019 can cause a viral pneumonia with additional extrapulmonary manifestations and complications. A large proportion of patients have underlying cardiovascular disease and/or cardiac risk factors. Factors associated with mortality include male sex, advanced age, and presence of comorbidities including hypertension, diabetes mellitus, cardiovascular diseases, and cerebrovascular diseases. Acute cardiac injury determined by elevated high-sensitivity troponin levels is commonly observed in severe cases and … Continue reading Potential Effects of #Coronaviruses on the #Cardiovascular System

Blood #pressure in frail older adults: associations with #cardiovascular outcomes and all-cause mortality

Blood pressure (BP) management in frail older people is challenging. An randomised controlled trial of largely non-frail older people found cardiovascular and mortality benefit with systolic (S) BP target <120 mmHg. However, all-cause mortality by attained BP in routine care in frail adults aged above 75 is unclear.. ..Risks of cardiovascular outcomes increased with SBPs >150 mmHg. Associations with mortality varied between non-frail <85 and … Continue reading Blood #pressure in frail older adults: associations with #cardiovascular outcomes and all-cause mortality

Olive Oil Consumption and Cardiovascular Risk in U.S. Adults

Olive oil intake has been associated with lower risk of cardiovascular disease (CVD) in Mediterranean populations, but little is known about these associations in the U.S population. ..During 24 years of follow-up, we documented 9,797 incident cases of CVD, including 6,034 CHD cases and 3,802 stroke cases. After adjusting for major diet and lifestyle factors, compared with non-consumers, those with higher olive oil intake (>1/2 … Continue reading Olive Oil Consumption and Cardiovascular Risk in U.S. Adults