The trajectory of inflammatory bowel disease in east and southeast Asia: transitioning from acceleration in incidence to compounding prevalence

The epidemiology of inflammatory bowel disease (IBD) progresses through four stages: emergence (stage 1), acceleration in incidence (stage 2), compounding prevalence (stage 3), and prevalence equilibrium (stage 4). Most early industrialised regions (Europe, North America, and Oceania) have reached stage 3, whereas many newly industrialised regions-those that predominantly industrialised after World War 2-are in stage… Continue reading The trajectory of inflammatory bowel disease in east and southeast Asia: transitioning from acceleration in incidence to compounding prevalence

Hospitalization, ICU admission, and mortality among diabetic patients with inflammatory bowel disease receiving SGLT-2 inhibitors: a retrospective cohort study from the global collaborative network

diabetes mellitus (T2DM) and inflammatory bowel disease (IBD) represent a high-risk population with competing comorbidities, complex medication regimens, and overlapping inflammatory pathways. Although the role of sodium-glucose co-transporter-2 (SGLT2) inhibitors in managing type 2 diabetes is well-established, their impact on outcomes in diabetic patients with coexisting IBD remains unclear. This study aimed to investigate the… Continue reading Hospitalization, ICU admission, and mortality among diabetic patients with inflammatory bowel disease receiving SGLT-2 inhibitors: a retrospective cohort study from the global collaborative network

Socioeconomic disparities in biologic persistence among patients with inflammatory bowel disease are associated with increased health care utilization

Introduction: Biologic persistence, defined as the total uninterrupted time on a biologic agent, is associated with improved outcomes in inflammatory bowel disease (#IBD ). However, social determinants of health (SDOH), such as socioeconomic status, may influence a patient's ability to access these medications. We aimed to better understand the relationship between socioeconomic status and biologic… Continue reading Socioeconomic disparities in biologic persistence among patients with inflammatory bowel disease are associated with increased health care utilization

Impact of tobacco use on inpatient outcomes in inflammatory bowel disease: a retrospective matched cohort study

#Tobacco plays a complex role in patients with inflammatory bowel disease (#IBD ). Its impact on inpatient outcomes of IBD needs additional study. We aimed to assess the impact of smoking on clinical outcomes in hospitalized patients with IBD. Methods We conducted a retrospective cohort study using data from the National Inpatient Sample (NIS) spanning… Continue reading Impact of tobacco use on inpatient outcomes in inflammatory bowel disease: a retrospective matched cohort study

#Hepatitis E Infection in Patients With Inflammatory Bowel Diseases: A Systematic Review and Meta-Analysis

Opportunistic infections are increasingly recognised in patients with inflammatory bowel disease ( #IBD ), particularly among those receiving immunosuppressive therapy. Hepatitis E virus ( #HEV ) is a leading cause of acute viral hepatitis worldwide, yet its relevance in IBD remains insufficiently clarified. This systematic review and meta-analysis aimed to explore the association between HEV… Continue reading #Hepatitis E Infection in Patients With Inflammatory Bowel Diseases: A Systematic Review and Meta-Analysis

Increased Prevalence of Pulmonary Diseases in Patients With Inflammatory Bowel Disease

Inflammatory bowel disease ( #IBD ) is a multisystem illness with intestinal and extraintestinal manifestations. We aimed to analyze the association of developing #pulmonary diseases (PDs) in patients with IBD.Methods: In this retrospective cohort study, TriNetX was used to identify patients with IBD who were prescribed at least one IBD-specific medication or advanced therapy. Patients… Continue reading Increased Prevalence of Pulmonary Diseases in Patients With Inflammatory Bowel Disease

Practical #guidelines on medical management of adults with moderate-to-severe #inflammatory bowel disease

Inflammatory bowel disease (IBD) is a chronic, relapsing inflammatory disorder that predominantly includes Crohn’s disease (CD) and ulcerative colitis (UC). IBD has emerged as a significant healthcare challenge in Saudi Arabia, with a more than fivefold increase in annual incidence over the past 2 decades. These guidelines promote high-quality, evidence-based care for adult patients with… Continue reading Practical #guidelines on medical management of adults with moderate-to-severe #inflammatory bowel disease

Association Between Pro-Inflammatory Potential of #Diet and Inflammatory Parameters in a Group of Patients with Inflammatory #Bowel Disease

Background: The etiopathogenesis of IBD is not fully known; however, both genetic and environmental risk factors, including diet, are contributors to the disease. The present study aimed to determine the effect of dietary inflammatory potential, assessed using the Dietary Inflammatory Index (DII), on disease activity and inflammatory markers, such as IL-6, IL-1β, and IL-10, in… Continue reading Association Between Pro-Inflammatory Potential of #Diet and Inflammatory Parameters in a Group of Patients with Inflammatory #Bowel Disease

Physiological Data Collected from #Wearable Devices Identify and Predict Inflammatory #Bowel Disease Flares

Wearable devices capture physiological signals non-invasively and passively. Many of these parameters have been linked to inflammatory bowel disease (IBD) activity. We evaluated the associative ability of several physiological metrics with IBD flares and how they change before the development of flare.MethodsParticipants throughout the United States answered daily disease activity surveys and wore an Apple… Continue reading Physiological Data Collected from #Wearable Devices Identify and Predict Inflammatory #Bowel Disease Flares