Cumulative evidence shows a linkage between gut microbiota pattern and depression through the brain-gut microbiome axis. The aim of this systematic review was to identify the alterations of the gut microbiota patterns in people with depression compared to healthy controls. A comprehensive literature search of human studies, published between January 2000 and June 2019, was … Continue reading Altered Composition of Gut #Microbiota in #Depression: A Systematic Review
Tag: gut-microbiota
HighlightsSerum gut-permeability markers LPB, LPS, and I-FABP are increased in RAMice with arthritis have increased gut permeability and intestinal inflammationBoth bacteria and leukocytes are needed to disrupt gut-barrier integrityPrevention of gut-barrier dysfunction in arthritis ameliorates joint inflammation Context and significanceRheumatoid arthritis is an autoimmune disorder characterized by chronic joint inflammation. Accumulating evidence suggests that changes … Continue reading #Intestinal barrier dysfunction plays an integral role in #arthritis pathology and can be targeted to ameliorate disease
A Western-style, high-fat diet promotes cardiovascular disease, in part because it is rich in choline, which is converted to trimethylamine (TMA) by the gut microbiota. However, whether diet-induced changes in intestinal physiology can alter the metabolic capacity of the microbiota remains unknown. Using a mouse model of diet-induced obesity, we show that chronic exposure to … Continue reading High- #fat diet–induced #colonocyte dysfunction escalates microbiota-derived trimethylamine N-oxide
Diet intervention with systems profiling reveals links in diet-microbiome-immune axis•High-fiber diet changes microbiome function and elicits personalized immune responses•Fermented-food diet increases microbiome diversity and decreases markers of inflammation SummaryDiet modulates the gut microbiome, which in turn can impact the immune system. Here, we determined how two microbiota-targeted dietary interventions, plant-based fiber and fermented foods, influence … Continue reading #Gut-microbiota-targeted #diets modulate human immune status
