Creutzfeldt-Jakob Disease After the COVID-19Vaccination

Reports of neurological problems are increasing for the clinical presentation of COVID-19

The clinical presentation reported in this study seemed to be a combination of nonspecific
complications of the systemic disease, inflammation of the cerebrovascular system, and the
effects of a direct viral infection. Creutzfeldt–Jakob disease, a spongiform encephalopathy
caused by prions, is characterized by a severe neurological destruction, which has an extremely
high mortality. In this publication, we presented a patient who was admitted to the Pamukkale
University Anesthesiology Intensive Care Units with the neurological findings that developed after
the COVID-19 vaccine (CoronaVac, Sinovac Life Sciences, Beijing, China).

The patient died due to
the progressive neurological disorders. In cases where rapidly progressive neurological disorders
are observed, Creutzfeldt–Jakob disease should be considered and the role of immunity-related
conditions in the progression of the disease should be investigated.