Atrial fibrillation and heart failure with reduced ejection fraction (HFrEF) are common sources of cardioembolism. While oral anticoagulation is strongly recommended for atrial fibrillation, there are marked variations in guideline recommendations for HFrEF due to uncertainty about net clinical benefit. This systematic review and meta-analysis evaluates the comparative association of oral anticoagulation with stroke and … Continue reading Association of Oral #Anticoagulation With #Stroke in Atrial #Fibrillation or Heart #Failure: A Comparative Meta-Analysis
Category: Neurology
A recent study suggested that the CHA2DS2-VASc score can risk stratify heart failure (HF) patients without atrial fibrillation (AF) for stroke. We performed a retrospective analysis using the national Veteran Affairs database to externally validate the findings. Crude incidence rates of end points were calculated. A Cox proportional model was used to study the association … Continue reading The #CHA2DS2-VASc Score for Risk Stratification of #Stroke in Heart Failure With-vs-Without Atrial #Fibrillation
Risks associated with fatigue that accumulates during work shifts have historically been managed through working time arrangements that specify fixed maximum durations of work shifts and minimum durations of time off. By themselves, such arrangements are not sufficient to curb risks to performance, safety, and health caused by misalignment between work schedules and the biological … Continue reading Guiding principles for determining work #shift duration and addressing the effects of work shift duration on performance, safety, and health: guidance from the American Academy of #Sleep Medicine and the Sleep Research Society
The case of a patient who experienced two facial palsies - one after the first and another after the second dose of the Pfizer-BioNTech COVID-19 vaccine - strongly suggests that Bell's palsy (facial nerve palsy of unknown cause) is linked to the Pfizer-BioNTech vaccine, doctors write in the journal BMJ Case Reports. They describe the … Continue reading Patient case strongly suggests link between #COVID-19 vaccine and #Bell’s palsy
