The #SARS-CoV-2 receptor-binding domain preferentially recognizes #blood group A

Key Points
The RBD of SARS-CoV-2 shares sequence similarity with an ancient lectin family known to bind blood group antigens.

SARS-CoV-2 RBD binds the blood group A expressed on respiratory epithelial cells, directly linking blood group A and SARS-CoV-2.

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