Background: Iron deficiency anemia (IDA) has been increasingly associated with Helicobacter pylori (H. pylori) infection, especially in developing countries.Objective: This study aimed to evaluate the association between H. pylori infection and IDA severity and to compare hematological parameters between H. pylori-positive and -negative adult patients attending a tertiary care hospital.Methodology: This was a cross-sectional analytical… Continue reading Association Between Helicobacter pylori Infection and Iron Deficiency Anemia in Adult Patients Attending a Tertiary Care Hospital
Category: Hematology
Maternal Bleeding Outcomes in Pregnant Women With Immune Thrombocytopenia (ITP): A National Database Study
Objective: Immune thrombocytopenic purpura (ITP) is a hematological disorder commonly affecting women of reproductive age, but limited studies explore the maternal morbidity in pregnant patients with ITP. This study aimed to investigate whether pregnant women with ITP are at higher risk of bleeding complications during and after delivery.Methods: We analyzed the National Inpatient Sample (NIS)… Continue reading Maternal Bleeding Outcomes in Pregnant Women With Immune Thrombocytopenia (ITP): A National Database Study
Impact of Iron Deficiency Anemia on Outcomes After Transcatheter Aortic Valve Implantation: Insights From the Nationwide Readmission Database From 2016 to 2021
Background: Transcatheter aortic valve implantation ( #TAVI ) has become an established intervention for severe symptomatic aortic stenosis, particularly in high-risk and elderly patients. Although #anemia is frequently encountered in this population, the specific role of iron deficiency anemia (IDA) in influencing outcomes following TAVI remains underexplored.Aims: This study aims to evaluate the impact of… Continue reading Impact of Iron Deficiency Anemia on Outcomes After Transcatheter Aortic Valve Implantation: Insights From the Nationwide Readmission Database From 2016 to 2021
Three vs 12-month #DAPT after implantation of biodegradable-polymer sirolimus-eluting coronary #stent : a randomised clinical trial
Early discontinuation of dual antiplatelet therapy (DAPT) within 3 months after implantation of drug-eluting stents may reduce bleeding risk without increasing ischaemic events. This study aimed to assess whether 3-month DAPT is as safe as the conventional 12-month regimen in patients treated with Firehawk stents, which have demonstrated 99.9% reendothelialisation at 3 months by optical… Continue reading Three vs 12-month #DAPT after implantation of biodegradable-polymer sirolimus-eluting coronary #stent : a randomised clinical trial
Clinical outcomes of #orthopaedic surgery patients with inferior vena #cava filter prophylaxis
AbstractPurpose: Orthopaedic surgery patients are at an elevated risk of venous thromboembolic events thus necessitating effective prophylaxis strategies.Methods: This IRB-approved, single-center retrospective study evaluated patients who underwent orthopaedic surgery and were protected with Inferior Vena Cava (IVC) filters from January 2007 to December 2021. Study outcomes include incidence of venous thromboembolism (VTE) in the form… Continue reading Clinical outcomes of #orthopaedic surgery patients with inferior vena #cava filter prophylaxis
#Erythrocytosis and #thromboembolic risks associated with #SGLT2 inhibitors in type 2 diabetes
This study aimed to determine if sodium-glucose co-transporter-2 inhibitors (SGLT2i) use in diabetic patients leads to erythrocytosis and increases the incidence of arterial and venous thrombosis events. This is a retrospective cohort study using records from over 50 U.S. healthcare organizations. Adults with type 2 diabetes who received SGLT2i therapy were compared to those on… Continue reading #Erythrocytosis and #thromboembolic risks associated with #SGLT2 inhibitors in type 2 diabetes
#Artificial #intelligence in #myeloid malignancies: Clinical applications of machine learning in myelodysplastic syndromes and acute myeloid #Leukemia
This review summarizes applications of machine learning (ML) in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS), spanning diagnosis, prognostication, treatment prediction, and research tools. In diagnostics, deep learning applied to bone marrow smears, peripheral blood films, and flow cytometry has shown high sensitivity and specificity, outperforming conventional methods. ML-driven unsupervised clustering and consensus classification… Continue reading #Artificial #intelligence in #myeloid malignancies: Clinical applications of machine learning in myelodysplastic syndromes and acute myeloid #Leukemia
#Tattoos as a risk factor for malignant #lymphoma: a population-based case–control study
BackgroundThe popularity of tattoos has increased dramatically over the last few decades. Tattoo ink often contains carcinogenic chemicals, e.g., primary aromatic amines, polycyclic aromatic hydrocarbons, and metals. The tattooing process invokes an immunologic response that causes translocation of tattoo ink from the injection site. Deposition of tattoo pigment in lymph nodes has been confirmed but the long-term… Continue reading #Tattoos as a risk factor for malignant #lymphoma: a population-based case–control study
#Nicotinamide enhances natural #killer cell function and yields remissions in patients with non-Hodgkin #lymphoma
Administration of haploidentical donor natural killer (NK) cells, rituximab, and IL-2 to patients with non-Hodgkin lymphoma (NHL) has been shown to be safe, but the objective response rate was low, suggesting that further strategies to improve NK cell engraftment and function are needed. Here, Cichocki and colleagues showed that supplementation with nicotinamide during ex vivo… Continue reading #Nicotinamide enhances natural #killer cell function and yields remissions in patients with non-Hodgkin #lymphoma
2 Medical News 