Quantifying physical differences of protein aggregates implicated in Alzheimer’s disease (AD), in blood, could provide crucial information on disease stages. Here, red blood cells (RBCs) from 50 patients with neurocognitive complaints and 16 healthy individuals were profiled using an atomic force microscope (AFM). AFM measurements revealed patient age– and stage of neurocognitive disorder–dependent differences in … Continue reading Spatial organization of #protein aggregates on red #blood cells as physical biomarkers of #Alzheimer’s disease pathology
Category: Hematology
The long-term risk for major bleeding in patients receiving extended (beyond the initial 3 to 6 months) anticoagulant therapy for a first unprovoked venous thromboembolism (VTE) is uncertain. Purpose:To determine the incidence of major bleeding during extended anticoagulation of up to 5 years among patients with a first unprovoked VTE, overall, and in clinically important … Continue reading Long-Term Risk for Major #Bleeding During Extended Oral Anticoagulant Therapy for First Unprovoked Venous #Thromboembolism
Studies have shown a link between homocysteine (Hcy) and heart diseases, kidney diseases, cerebrovascular diseases, liver diseases, and other pathological conditions. However, the relationship between Hcy and liver fibrosis (LF) is unclear. Here, we studied the link between plasma Hcy concentration and LF. Methods: We determined and recorded the plasma Hcy concentration, general biochemical parameters, … Continue reading Plasma Levels of #Homocysteine is Associated with Liver #Fibrosis in Health Check-Up Population
A new syndrome of vaccine-induced immune thrombotic thrombocytopenia (VITT) has emerged as a rare side-effect of vaccination against COVID-19. Cerebral venous thrombosis is the most common manifestation of this syndrome but, to our knowledge, has not previously been described in detail. We aimed to document the features of post-vaccination cerebral venous thrombosis with and without … Continue reading #Cerebral venous #thrombosis after vaccination against #COVID-19 in the UK: a multicentre cohort study
