Editor’s summary
Polycystic ovary syndrome is a common endocrine condition in women of reproductive age. Its manifestations include androgen excess and other hormonal changes, menstrual cycle alterations, infertility, and metabolic abnormalities. Artemisinins are plant-derived compounds that are best known for their antimalarial properties but have also been shown to have some beneficial metabolic effects. Liu et al. demonstrated that artemisinins can also relieve the endocrine manifestations of polycystic ovarian syndrome in multiple rodent models and in human patients, suggesting a potential approach to treating multiple facets of this endocrine disorder (see the Perspective by Stener-Victorin). —Yevgeniya Nusinovich
https://www.science.org/doi/10.1126/science.adk5382
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