Background: Population studies report health benefits from coffee intake. Coffee has up to 100 biologic compounds with caffeine most well known. The effects of coffee subtypes on cardiovascular(CV) outcomes is unclear. We aim to evaluate the associations between coffee subtypes and incident arrhythmia, CV disease (CVD), and total/ CV mortality
Methods: Participant responses to coffee amount and type(ground, instant, ordecaffeinated) was obtained from the UK Biobank. Coffee intake was divided into 0, <1, 1, 2-3, 4-5, >5 cups/day. Associations between coffee subtypes and CV/ mortality endpoints were assessed using Cox regression
Results: There were 73027 ground, 167399 instant, 57615 decaf coffee drinkers and 84494 non coffee drinkers. Ground and instant coffee intake between 1-5 cups/day was associated with reduced arrhythmia, CVD, coronary disease, cardiac failure (CCF) and stroke risks. Lowest risk for CVD was seen at 2-3 cups/day for ground (HR0.83, CI 0.79-0.87), and instant (HR0.91, CI 0.88-0.95). Decaf coffee had a neutral effect against incident arrhythmia and CVD, with the exception of CCF. Total/ CV mortality risk was reduced with all subtypes, with the lowest total mortality at 2-3 cups/day for ground (HR 0.74, CI 0.69-0.79), instant (HR0.90, CI 0.86-0.94), and decaf (HR0.85, CI 0.80-0.91, all p <0.01)

Conclusion: Ground/ instant coffee reduced arrhythmia/ CVD risk, although all types reduced mortality. Non-caffeine compounds are likely important in improved survival in coffee drinkers

https://www.abstractsonline.com/pp8/#!/10461/presentation/12593