Selected Soybean Varieties Regulate Hepatic LDL-Cholesterol Homeostasis Depending on Their Glycinin:β-Conglycinin Ratio

Clinical studies indicate that the consumption of soybean protein might reduce cholesterol and LDL levels preventing the development of atherosclerotic cardiovascular diseases. However, soybean variety can influence soybean protein profile and therefore affect soybean protein health-promoting properties. This study investigated the composition and effects of nineteen soybean varieties digested under simulated gastrointestinal conditions on hepatic …

Continue reading Selected Soybean Varieties Regulate Hepatic LDL-Cholesterol Homeostasis Depending on Their Glycinin:β-Conglycinin Ratio

Short-Term Grape Consumption Diminishes UV-Induced Skin Erythema

Over three million Americans are affected by skin cancer each year, largely as a result of exposure to sunlight. The purpose of this study was to determine the potential of grape consumption to modulate UV-induced skin erythema. With 29 human volunteers, we report that nine demonstrated greater resistance to UV irradiation of the skin after …

Continue reading Short-Term Grape Consumption Diminishes UV-Induced Skin Erythema

Association of Eating and Sleeping Intervals With Weight Change Over Time: The Daily24 Cohort

BackgroundWe aim to evaluate the association between meal intervals and weight trajectory among adults from a clinical cohort.Methods and ResultsThis is a multisite prospective cohort study of adults recruited from 3 health systems. Over the 6‐month study period, 547 participants downloaded and used a mobile application to record the timing of meals and sleep for …

Continue reading Association of Eating and Sleeping Intervals With Weight Change Over Time: The Daily24 Cohort

Association of Eating and Sleeping Intervals With Weight Change Over Time: The Daily24 Cohort

BackgroundWe aim to evaluate the association between meal intervals and weight trajectory among adults from a clinical cohort.Methods and ResultsThis is a multisite prospective cohort study of adults recruited from 3 health systems. Over the 6‐month study period, 547 participants downloaded and used a mobile application to record the timing of meals and sleep for …

Continue reading Association of Eating and Sleeping Intervals With Weight Change Over Time: The Daily24 Cohort

Increased Intake of Both Caffeine and Non-Caffeine Coffee Components Is Associated with Reduced NAFLD Severity in Subjects with Type 2 Diabetes

Coffee may protect against non-alcoholic fatty liver disease (NAFLD), but the roles of the caffeine and non-caffeine components are unclear. Coffee intake by 156 overweight subjects (87% with Type-2-Diabetes, T2D) was assessed via a questionnaire, with 98 subjects (all T2D) also providing a 24 h urine sample for quantification of coffee metabolites by LC–MS/MS. NAFLD …

Continue reading Increased Intake of Both Caffeine and Non-Caffeine Coffee Components Is Associated with Reduced NAFLD Severity in Subjects with Type 2 Diabetes