Objective
To investigate the association between chrononutrition and glycemic control parameters throughout the pregnancy in women with diabetes mellitus (DM).
Methods
Cross-sectional study with 117 pregnant women with pregestational DM. Food consumption was assessed using 24-h dietary recalls in the second and third trimesters of pregnancy. Chrononutrition parameters included number of eating episodes, eating pattern, mealtimes, and caloric intake. Glycemic control was measured by fasting plasma glucose and glycated hemoglobin. Multivariate linear regression models examined the associations.
Results
Higher caloric consumption between 6 p.m. and 5.59 a.m. was associated with increased fasting glycemia in the second (ß adjusted = 23.77, P = 0.008) and third (P = 0.027; ß adjusted = 0.05, P = 0.006) trimesters, but consuming evening snack before dinner, without increasing nighttime calories, was associated with better glucose control in the second trimester (P = 0.022). In the third trimester, later breakfast followed by later morning snack was associated with lower glycated hemoglobin (P = 0.049; ß adjusted = −0.30, P = 0.012).
Conclusion
Chrononutritional parameters and caloric distribution influence glycemic control in pregnant women with DM. These findings suggest that individualized nutritional care should include advising pregnant women with DM to consider limiting their nighttime energy intake, consuming an evening snack before dinner, and adjusting their morning meal timing to optimize glycemic control.
https://www.sciencedirect.com/science/article/abs/pii/S0899900726000675
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