This study finds that a high-fat diet suppresses a crucial gut protein, Jak3, leading to Alzheimer’s-like brain changes in mice. It underscores the importance of managing diabetes or avoiding it through diet to reduce Alzheimer’s risk.
The findings illuminate a potential path from diet through gut inflammation to brain health, offering hope for preventative strategies.
Key Facts:
Molecular Connection: The suppression of the Jak3 protein in the gut due to a high-fat diet can initiate a cascade of inflammation leading to Alzheimer’s-like symptoms in the brain.
Preventative Potential: Controlling or avoiding diabetes through diet and blood sugar management could significantly reduce the risk of developing Alzheimer’s disease.
Broad Implications: Given the vast number of U.S. adults with prediabetes, lifestyle changes to prevent diabetes may also mitigate Alzheimer’s risk, highlighting the critical intersection of diet, metabolic health, and neurodegeneration.
https://neurosciencenews.com/diet-diabetes-dementia-25802/
Skip to content
Every Day, 2 Medical News from the most Trusted Journals
2 Medical News 