Hormone therapy as a possible solution for post #menopausal women with #nocturia results of a pilot trial

To observe the impact of different hormonal treatment options on nocturia, its causative factors and bother in postmenopausal women. Methods: This prospective study recruited 245 postmenopausal women and divided them into four treatment groups based on patient's choice: Estrogen + Progesterone (E+P), Estrogen-only in patients with a prior hysterectomy, tissue-selective estrogen complex (TSEC) and no… Continue reading Hormone therapy as a possible solution for post #menopausal women with #nocturia results of a pilot trial

Effect of Marine #Omega-3 Fatty Acid and Vitamin #D Supplementation on Incident Atrial #Fibrillation

Atrial fibrillation (AF) is the most common heart rhythm disturbance, continues to increase in incidence, and results in significant morbidity and mortality. The marine omega-3 fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), and vitamin D have been reported to have both benefits and risks with respect to incident AF, but large-scale, long-term randomized… Continue reading Effect of Marine #Omega-3 Fatty Acid and Vitamin #D Supplementation on Incident Atrial #Fibrillation

Fructose- and sucrose- but not glucose-sweetened #beverages promote hepatic de novo #lipogenesis: A randomized controlled trial

Excessive fructose intake associates with increased de novo lipogenesis, blood triglycerides, and hepatic insulin resistance. Whether fructose-specific effects on lipid metabolism in healthy men exist independently from overfeeding needs clarification. Methods 94 subjects were studied in this double-blind, randomized trial. They were assigned to daily consumption of sugar-sweetened beverages (SSB) containing moderate amounts of fructose,… Continue reading Fructose- and sucrose- but not glucose-sweetened #beverages promote hepatic de novo #lipogenesis: A randomized controlled trial

Sex Differences in the Association of Body Composition and #Cardiovascular Mortality

To determine whether differences in body composition contribute to sex differences in cardiovascular disease (CVD) mortality, we investigated the relationship between components of body composition and CVD mortality in healthy men and women. Methods and Results Dual energy x‐ray absorptiometry body composition data from the National Health and Nutrition Examination Survey 1999–2004 and CVD mortality… Continue reading Sex Differences in the Association of Body Composition and #Cardiovascular Mortality

Empiric #antibiotics for community-acquired #pneumonia in adult patients: a systematic review and a network meta-analysis

The main aim of this network meta-analysis is to identify the empiric antibiotic (Em-ATB) with the highest probability of being the best (HPBB) in terms of (1) cure rate and (2) mortality rate in hospitalised patients with community acquired pneumonia (CAP) . Method Inclusion criteria: (1) adult patients (>16 years old) diagnosed with CAP that required… Continue reading Empiric #antibiotics for community-acquired #pneumonia in adult patients: a systematic review and a network meta-analysis

Effects of Stressful Events and Perceived #Stress on Cognitive Change Among #Depressed Older Adults

Stress is thought to exacerbate cognitive decline in older adults, especially those with late life depression (LLD); however, the specific aspects of stress that are especially deleterious and the aspects of cognition they affect are not clear. For example, it is not known whether the effects result from the exposure to stressful life events or… Continue reading Effects of Stressful Events and Perceived #Stress on Cognitive Change Among #Depressed Older Adults

Circulating Vitamin #D levels status and clinical prognostic indices in #COVID-19 patients

Several immune mechanisms activate in COVID-19 pathogenesis. Usually, coronavirus infection is characterized by dysregulated host immune responses, interleukine-6 increase, hyper-activation of cytotoxic CD8 T lymphocytes. Interestingly, Vitamin D deficiency has been often associated with altered immune responses and infections. In the present study, we evaluated Vitamin D plasma levels in patients affected with different lung… Continue reading Circulating Vitamin #D levels status and clinical prognostic indices in #COVID-19 patients

Effectiveness of Electroacupuncture or Auricular #Acupuncture vs Usual Care for Chronic Musculoskeletal Pain Among #Cancer Survivors The PEACE Randomized Clinical Trial

The opioid crisis creates challenges for cancer pain management. Acupuncture confers clinical benefits for chronic nonmalignant pain, but its effectiveness in cancer survivors remains uncertain. Objective To determine the effectiveness of electroacupuncture or auricular acupuncture for chronic musculoskeletal pain in cancer survivors. Design, Setting, and Participants The Personalized Electroacupuncture vs Auricular Acupuncture Comparativeness Effectiveness (PEACE)… Continue reading Effectiveness of Electroacupuncture or Auricular #Acupuncture vs Usual Care for Chronic Musculoskeletal Pain Among #Cancer Survivors The PEACE Randomized Clinical Trial

A Primary Care Agenda for #Brain Health: A Scientific Statement From the American Heart Association

A healthy brain is critical for living a longer and fuller life. The projected aging of the population, however, raises new challenges in maintaining quality of life. As we age, there is increasing compromise of neuronal activity that affects functions such as cognition, also making the brain vulnerable to disease. Once pathology-induced decline begins, few… Continue reading A Primary Care Agenda for #Brain Health: A Scientific Statement From the American Heart Association