Preliminary studies have demonstrated the efficacy of Transcendental Meditation (TM) for treating posttraumatic stress disorder (PTSD). The present study extended previous research with a pilot trial of TM as a treatment for PTSD via a single‐blinded, randomized controlled design. veterans with PTSD (N = 40) were assigned to a TM intervention or treatment‐as‐usual (TAU) control… Continue reading A Pilot Randomized Controlled Trial of Transcendental #Meditation as Treatment for #Posttraumatic Stress Disorder in Veterans
Benzedrex (#propylhexedrine): Drug Safety Communication – FDA Warns that Abuse and Misuse of the Nasal #Decongestant Causes Serious Harm
AUDIENCE: Consumer, Patient, Health Professional, Pharmacy ISSUE: The FDA is warning that the abuse and misuse of the over-the-counter (OTC) nasal decongestant propylhexedrine can lead to serious harm such as heart and mental health problems. Some of these complications, which include fast or abnormal heart rhythm, high blood pressure, and paranoia, can lead to hospitalization,… Continue reading Benzedrex (#propylhexedrine): Drug Safety Communication – FDA Warns that Abuse and Misuse of the Nasal #Decongestant Causes Serious Harm
#Aspirin Use Is Associated With Decreased Mechanical Ventilation, Intensive Care Unit Admission, and In-Hospital Mortality in Hospitalized Patients With #Coronavirus Disease 2019
Coronavirus disease-2019 (COVID-19) is associated with hypercoagulability and increased thrombotic risk in critically ill patients. To our knowledge, no studies have evaluated whether aspirin use is associated with reduced risk of mechanical ventilation, intensive care unit (ICU) admission, and in-hospital mortality. METHODS: A retrospective, observational cohort study of adult patients admitted with COVID-19 to multiple… Continue reading #Aspirin Use Is Associated With Decreased Mechanical Ventilation, Intensive Care Unit Admission, and In-Hospital Mortality in Hospitalized Patients With #Coronavirus Disease 2019
Association of spontaneous #abortion with all cause and cause specific premature #mortality: prospective cohort study
To investigate the association of spontaneous abortion with the risk of all cause and cause specific premature mortality (death before the age of 70). Design Prospective cohort study. Setting The Nurses’ Health Study II (1993-2017), United States. Participants 101 681 ever gravid female nurses participating in the Nurses’ Health Study II. Main outcomes measures Lifetime occurrence… Continue reading Association of spontaneous #abortion with all cause and cause specific premature #mortality: prospective cohort study
OR10-1 – Efficacy of High-Intensity Intermittent #Training for Improving Cardio-Metabolic Health in Women With #Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) is a common and complex endocrinopathy with significant metabolic and reproductive manifestations, carrying a major health and economic burden. Consistent improvements in clinical outcomes have been reported as a result of exercise training, but shortfalls with exercise prescription are evident. Research suggests that high-intensity intermittent training (HIIT) is feasible, well tolerated… Continue reading OR10-1 – Efficacy of High-Intensity Intermittent #Training for Improving Cardio-Metabolic Health in Women With #Polycystic Ovary Syndrome
Utility of bedside leucocyte esterase testing to rule out septic #arthritis
Suspected septic arthritis is a common presentation to EDs. The underlying diagnosis is often non-infective pathology. Differentiating between aetiologies is difficult. A bedside test with high negative predictive value (NPV) may allow safe discharge of patients, reduce the time in the ED, hospital admission and associated costs. This study aims to evaluate the NPV of… Continue reading Utility of bedside leucocyte esterase testing to rule out septic #arthritis
#Semaglutide 2·4 mg once a week in adults with #overweight or #obesity, and type 2 diabetes (STEP 2): a randomised, double-blind, double-dummy, placebo-controlled, phase 3 trial
Background This trial assessed the efficacy and safety of the GLP-1 analogue once a week subcutaneous semaglutide 2·4 mg versus semaglutide 1·0 mg (the dose approved for diabetes treatment) and placebo for weight management in adults with overweight or obesity, and type 2 diabetes. Methods This double-blind, double-dummy, phase 3, superiority study enrolled adults with… Continue reading #Semaglutide 2·4 mg once a week in adults with #overweight or #obesity, and type 2 diabetes (STEP 2): a randomised, double-blind, double-dummy, placebo-controlled, phase 3 trial
The Value of Total #Knee Replacement in Patients With Knee #Osteoarthritis and a Body Mass Index of 40 kg/m2 or Greater A Cost-Effectiveness Analysis
Total knee replacement (TKR) is an effective and cost-effective strategy for treating end-stage knee osteoarthritis. Greater risk for complications among TKR recipients with a body mass index (BMI) of 40 kg/m2 or greater has raised concerns about the value of TKR in this population. Objective: To assess the value of TKR in recipients with a… Continue reading The Value of Total #Knee Replacement in Patients With Knee #Osteoarthritis and a Body Mass Index of 40 kg/m2 or Greater A Cost-Effectiveness Analysis
Hormone therapy as a possible solution for post #menopausal women with #nocturia results of a pilot trial
To observe the impact of different hormonal treatment options on nocturia, its causative factors and bother in postmenopausal women. Methods: This prospective study recruited 245 postmenopausal women and divided them into four treatment groups based on patient's choice: Estrogen + Progesterone (E+P), Estrogen-only in patients with a prior hysterectomy, tissue-selective estrogen complex (TSEC) and no… Continue reading Hormone therapy as a possible solution for post #menopausal women with #nocturia results of a pilot trial