Longitudinal associations of childhood fitness and obesity profiles with midlife cognitive function: an Australian cohort study

ObjectivesClusters of low fitness and high obesity in childhood are associated with poorer health outcomes in later life, however their relationship with cognition is unknown. Identifying such profiles may inform strategies to reduce risk of cognitive decline. This study examined whether specific profiles of childhood fitness and obesity were associated with midlife cognition. DesignProspective study. …

Continue reading Longitudinal associations of childhood fitness and obesity profiles with midlife cognitive function: an Australian cohort study

Clustering of COPD patients and their response to pulmonary rehabilitation

Background and objectivePulmonary rehabilitation (PR) is fundamental in the management of chronic obstructive pulmonary disease (COPD). COPD patients show a large clinical heterogeneity that may influence their response to PR. Identification of homogeneous clusters of patients who may or may not respond to PR is important to personalize patient care. This study aimed at identifying …

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Muscle-strengthening activities are associated with lower risk and mortality in major non-communicable diseases: a systematic review and meta-analysis of cohort studies

Objective To quantify the associations between muscle-strengthening activities and the risk of non-communicable diseases and mortality in adults independent of aerobic activities. Design Systematic review and meta-analysis of prospective cohort studies. Data sources MEDLINE and Embase were searched from inception to June 2021 and the reference lists of all related articles were reviewed. Eligibility criteria …

Continue reading Muscle-strengthening activities are associated with lower risk and mortality in major non-communicable diseases: a systematic review and meta-analysis of cohort studies

Non-target screening for the identification of migrating compounds from reusable plastic bottles into drinking water

Highlights•Migration of > 400 plastic related and > 3500 dishwasher related compounds. •The dishwashing process increased the migration of plastic related compounds. •Oligomers suspected from polycaprolactone (PCL) were migrating. •Three of the identified photoinitiators have possible endocrine disrupting effects. •Diethyltoluamide (DEET) may have been formed from the plasticizer laurolactam. AbstractReusable plastic sports bottles are used …

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Association of Physical Activity Level With Risk of Dementia in a Nationwide Cohort in Korea

Current guidelines recommend 500 to 999 metabolic equivalent (MET)–minutes per week (MET-min/wk) of regular physical activity. However, evidence regarding the association between light-intensity physical activity (LPA) and dementia in older adults is inconsistent. Objective To assess the association between physical activity and new-onset dementia, focusing on the dose-response association between physical activity and dementia and …

Continue reading Association of Physical Activity Level With Risk of Dementia in a Nationwide Cohort in Korea