Objective: The purpose of the study was to assess the relationship between variations in vitamin D levels, sarcopenia, and the fat-free mass index (FFMI) in individuals 65 years of age and above.Materials and methods: This retrospective study included 215 individuals aged ≥65 years who were followed at a geriatric outpatient clinic between January 2024 and… Continue reading EXPRESS: Vitamin D variability might be linked to sarcopenia, especially with decreased muscle mass in older patients: a retrospective longitudinal study
Category: supplements
Curcumin Suppresses Growth of Recurrent Colorectal Adenoma After Endoscopic Resection: A Randomized, Double-Blind, Placebo-Controlled, Multicenter Trial
Introduction: Experimental and limited clinical studies suggest that curcumin has chemopreventive activity in the colorectum. This large-scale clinical trial evaluated the efficacy and safety of curcumin in patients with previously endoscopically resected colorectal neoplasia.Methods: This randomized, double-blind, placebo-controlled multicenter trial enrolled patients with previously resected colorectal neoplasia. Eligible patients were randomly assigned (1:1), using a… Continue reading Curcumin Suppresses Growth of Recurrent Colorectal Adenoma After Endoscopic Resection: A Randomized, Double-Blind, Placebo-Controlled, Multicenter Trial
Exploring the link between water-soluble vitamins and aging-associated immune system status
Background: #Aging is associated with numerous physiological changes that contribute to immunosenescence and inflammaging, resulting in a decline in immune defense and an increased susceptibility to infections. Older adults are at risk of inadequate dietary intake and suboptimal supply of micronutrients, including water-soluble #vitamins, even those generally considered sufficient in the overall population. These deficiencies… Continue reading Exploring the link between water-soluble vitamins and aging-associated immune system status
Revisiting the Role of Vitamin D in Fracture Prevention in the Era of Mega-Trials
For decades, vitamin #D has been a cornerstone of preventive medicine. However, recent large-scale randomized controlled trials have failed to replicate the broad benefits previously observed in epidemiological studies, particularly with respect to fracture and fall prevention in vitamin D-replete populations. Moreover, growing evidence suggesting an increased fall risk associated with highdose bolus administration has… Continue reading Revisiting the Role of Vitamin D in Fracture Prevention in the Era of Mega-Trials
Over-the-Counter #Supplement Overuse: A Rare Potential Cause of #Arsenic Poisoning and #Bradycardia
A 71-year-old woman with no significant past medical history presented with progressive cognitive decline, fatigue, and weight loss over two years. Her symptoms included bradycardia, anxiety, depression, and mild dyspnea on exertion. The patient followed a strict diet fortified with smoothies and an extensive regimen of 26 dietary #supplements , consumed regularly over five years.… Continue reading Over-the-Counter #Supplement Overuse: A Rare Potential Cause of #Arsenic Poisoning and #Bradycardia
#Nicotinamide for #Skin #Cancer Chemoprevention
Importance Nicotinamide supplementation has been studied as a chemopreventive medication for reducing skin cancer risk, but large-scale data are limited.Objective To determine the clinical efficacy of nicotinamide supplementation for skin cancer prevention in the general population and among solid organ transplant recipients.Design, Setting, and Participants A retrospective cohort study was conducted using electronic health record… Continue reading #Nicotinamide for #Skin #Cancer Chemoprevention
Dietary vitamin #K intake associates with reduced all-cause #mortality in non-alcoholic #fatty #liver disease patients
This study aimed to investigate the association between dietary vitamin K intake and all-cause mortality in individuals with non-alcoholic fatty liver disease (NAFLD). We analyzed data from 7857 NAFLD participants in the National Health and Nutrition Examination Survey (NHANES 2005–2018) linked to mortality outcomes from the National Death Index (NDI). Dietary vitamin K intake was… Continue reading Dietary vitamin #K intake associates with reduced all-cause #mortality in non-alcoholic #fatty #liver disease patients
#Mineral Intake and #Depression: A Cross-Sectional Comparative Study Based on National Health and Nutrition Examination Surveys in Korea and the United States
Background/Objectives: Depression is a major global health burden, and previous studies suggest that nutrient deficiencies may contribute to its development. However, research on mineral intake and depression, particularly sodium and potassium, is limited. We conducted a cross-sectional analysis of data from the National Health and Nutrition Examination Survey in Korea (KNHANES) and the United States… Continue reading #Mineral Intake and #Depression: A Cross-Sectional Comparative Study Based on National Health and Nutrition Examination Surveys in Korea and the United States
Vitamin #D3 and marine ω-3 fatty acids supplementation and leukocyte #telomere length: 4-year findings from the VITamin D and OmegA-3 TriaL (VITAL) randomized controlled trial
Limited studies suggest that vitamin D or omega 3 fatty acids (n–3 FAs) supplementation may be beneficial for telomere maintenance; however, evidence from large randomized clinical trials is lacking. We hypothesized that vitamin D or n–3 FAs supplementation reduce leukocyte telomere length (LTL) attrition over time by leveraging the VITamin D and OmegA-3 TriaL (VITAL)… Continue reading Vitamin #D3 and marine ω-3 fatty acids supplementation and leukocyte #telomere length: 4-year findings from the VITamin D and OmegA-3 TriaL (VITAL) randomized controlled trial
