Background: Studies show variable results on health outcomes of isolated diastolic hypertension (IDH); however, data are scarce on its association with early kidney injury.Methods: We analyzed the Korea National Health and Nutrition Examination Survey data (2011-2014 and 2019-2024) in adults ≥19 years. After excluding those taking antihypertensive medication or with established kidney disease, participants were… Continue reading Association of isolated systolic and diastolic hypertension with moderately increased albuminuria: the Korea National Health and Nutrition Examination Survey
Category: Hypertension
Efficacy and safety of lorundrostat in uncontrolled hypertension: a systematic review, meta-analysis, and meta-regression
Background: Uncontrolled hypertension (UH), a severe form of hypertension, persists despite the use of three or more antihypertensive medications. Its growing prevalence, particularly in patients with comorbidities, necessitates novel therapeutic options. Lorundrostat, a selective aldosterone synthase inhibitor, presents a promising mechanism of action by directly reducing aldosterone synthesis while sparing cortisol production, potentially offering an… Continue reading Efficacy and safety of lorundrostat in uncontrolled hypertension: a systematic review, meta-analysis, and meta-regression
Renal denervation triage tool: a practical approach to the management of resistant hypertension
Despite the availability of medications and advocacy for lifestyle interventions, over half of individuals with hypertension do not achieve recommended treatment goals owing to limitations with medications, such as high cost, side effects, and poor adherence. Renal denervation (RDN), a minimally invasive endovascular procedure targeting sympathetic nerves near the renal arteries, is gaining recognition as… Continue reading Renal denervation triage tool: a practical approach to the management of resistant hypertension
Blood Pressure Phenotypes and Cardio-Kidney Outcomes: Findings From UK Biobank Data
Background: Hypertension is a leading cause of cardio-kidney outcomes (CKO). However, distinct blood pressure (BP) phenotypes and their effect on CKO remain underexplored. This study aimed to evaluate the independent contributions of BP phenotypes to CKO.Methods: This prospective, population-based study included UK Biobank participants enrolled between 2006 and 2010 with baseline systolic BP ≥90 mm… Continue reading Blood Pressure Phenotypes and Cardio-Kidney Outcomes: Findings From UK Biobank Data
Degree of urbanization and the prevalence of hypertension and diabetes mellitus in South Korea (Insight from Gyeonggi Province): A cross-sectional analysis with temporal trends, 2008-2023
Background: Despite South Korea's achievement of Universal Health Coverage (UHC), regional health inequities persist as a significant public health challenge. Traditional urban-rural classifications often fail to capture the nuanced spatial dynamics of modern settlement patterns. This study aimed to evaluate the prevalence of hypertension (HTN) and diabetes mellitus (DM) across the urbanization gradient-Cities, Urbanized, and… Continue reading Degree of urbanization and the prevalence of hypertension and diabetes mellitus in South Korea (Insight from Gyeonggi Province): A cross-sectional analysis with temporal trends, 2008-2023
Effect of relative handgrip strength and back muscle strength on the incidence of hypertension: 18-year follow-up in a population-based cohort study
Substantial evidence supports an association between physical #exercises and #hypertension. However, the role of muscle #strength, such as hand grip strength (HGS) and back muscle strength (BMS), remains unclear in this relationship. This study investigated whether low BMS and HGS accelerated incident hypertension in a population-based prospective study. A total 3,038 non-hypertensive subjects aged 40-69… Continue reading Effect of relative handgrip strength and back muscle strength on the incidence of hypertension: 18-year follow-up in a population-based cohort study
Bridging the Gap: Using an Asynchronous E-Learning Module to Improve Internal Medicine Residents’ Confidence and Preparedness in Ambulatory Blood Pressure Monitoring Interpretation
Background: Ambulatory blood #pressure monitoring (ABPM) is considered a reference standard for diagnosing #hypertension and is recommended for out-of-office blood pressure assessment, yet internal medicine residents receive limited training in its interpretation. We conducted a needs assessment to identify gaps in hypertension and ABPM education and developed an asynchronous e-learning module to address these deficiencies.… Continue reading Bridging the Gap: Using an Asynchronous E-Learning Module to Improve Internal Medicine Residents’ Confidence and Preparedness in Ambulatory Blood Pressure Monitoring Interpretation
Blood Pressure Control and Mortality Among US Veterans
Background: Intensive blood #pressure (#BP) control reduces mortality and cardiovascular disease in clinical trials. However, real-world BP measurements often differ from standardized protocols. We evaluated the impact of real-world systolic BP on mortality among US Veterans.Methods: We conducted a retrospective cohort study of Veterans with hypertension, defined by diagnostic codes, antihypertensive prescriptions, or ≥2 office… Continue reading Blood Pressure Control and Mortality Among US Veterans
The impact of blood pressure variability and African Caribbean ethnicity on the progression of diabetic kidney disease in type 1 diabetes
Aims/hypothesis: Blood #pressure variability (BPV) is a risk factor for #kidney disease progression in hypertension and type 2 diabetes; however, the role of BPV in kidney disease in type 1 diabetes is unknown. The aim of this study was therefore to determine whether BPV has an impact on kidney disease progression in an ethnically diverse… Continue reading The impact of blood pressure variability and African Caribbean ethnicity on the progression of diabetic kidney disease in type 1 diabetes
