#Psilocybin induces rapid and persistent growth of dendritic spines in frontal cortex in vivo

Psilocybin ameliorates stress-related behavioral deficit in mice•Psilocybin increases spine density and spine size in frontal cortical pyramidal cells•Psilocybin-evoked structural remodeling is persistent for at least 1 month•The dendritic rewiring is accompanied by elevated excitatory neurotransmission SummaryPsilocybin is a serotonergic psychedelic with untapped therapeutic potential. There are hints that the use of psychedelics can produce neural … Continue reading #Psilocybin induces rapid and persistent growth of dendritic spines in frontal cortex in vivo