Sleep problems are both symptoms of and modifiable risk factors for many psychiatric disorders. Wrist-worn accelerometers enable objective measurement of sleep at scale. Here, we aimed to examine the association of accelerometer-derived sleep measures with psychiatric diagnoses and polygenic risk scores in a large community-based cohort. Methods and findingsIn this post hoc cross-sectional analysis of … Continue reading Association of accelerometer-derived #sleep measures with lifetime #psychiatric diagnoses: A cross-sectional study of 89,205 participants from the UK Biobank
Category: Psychiatry
Sleep loss is reported to influence affective processing, causing changes in overall mood and altering emotion regulation. These aspects of affective processing are seldom investigated together, making it difficult to determine whether total sleep deprivation has a global effect on how affective stimuli and emotions are processed, or whether specific components of affective processing are … Continue reading Total #sleep deprivation reduces top-down regulation of #emotion without altering bottom-up affective processing
To investigate the preliminary efficacy of a high n-3 plus low n-6 (H3-L6) dietary intervention in improving mood stability in Bipolar Disorder (BD) when compared to dietary intervention with usual U.S. levels of n-6 and n-3 polyunsaturated fatty acid (PUFA) intakes (control diet, CD). MethodsThis 2-arm, parallel-group, randomized, modified double-blind, controlled 48-week study of 12-week … Continue reading Adjunctive #dietary intervention for #bipolar disorder: a randomized, controlled, parallel-group, modified double-blinded trial of a high n-3 plus low n-6 diet
Emotional dysregulation leading to clinically significant anger and aggression is a common and substantial concern for youth and their families. While psychotropic medications and cognitive behavioral therapies can be effective, these modalities suffer from drawbacks such as significant side effects, high rates of attrition, and lack of real-world skill translation. Regulate and Gain Emotional Control … Continue reading A “Proof of Concept” Randomized Controlled Trial of a Video Game Requiring Emotional Regulation to Augment #Anger Control Training
