The purpose of this updated guidance statement is to guide clinicians on screening for colorectal cancer (CRC) in asymptomatic average-risk adults. The intended audience is all clinicians. The population is asymptomatic adults at average risk for CRC.Methods:This updated guidance statement was developed using recently published and critically appraised clinical guidelines from national guideline developers since… Continue reading Screening for Colorectal Cancer in Asymptomatic Average-Risk Adults: A Guidance Statement From the American College of Physicians (Version 2)
Differential network interactions between #psychosocial factors, #mental health, and health-related quality of life in women and men
Psychosocial factors affect mental health and health-related quality of life (HRQL) in a complex manner, yet gender differences in these interactions remain poorly understood. We investigated whether psychosocial factors such as social support and personal and work-related concerns impact mental health and HRQL differentially in women and men during the first year of the COVID-19… Continue reading Differential network interactions between #psychosocial factors, #mental health, and health-related quality of life in women and men
Low-Dose #Aspirin and the Risk of #Stroke and Intracerebral #Bleeding in Healthy Older People Secondary Analysis of a Randomized Clinical Trial
Low-dose aspirin has been widely used for primary and secondary prevention of stroke. The balance between potential reduction of ischemic stroke events and increased intracranial bleeding has not been established in older individuals.Objective To establish the risks of ischemic stroke and intracranial bleeding among healthy older people receiving daily low-dose aspirin.Design, Setting, and Participants This secondary analysis… Continue reading Low-Dose #Aspirin and the Risk of #Stroke and Intracerebral #Bleeding in Healthy Older People Secondary Analysis of a Randomized Clinical Trial
#Ultra-processed #food consumption is associated with all-cause and #cardiovascular mortality in participants with type 2 #diabetes independent of diet quality: a prospective observational cohort study
BackgroundNutritional strategies for prevention and management of type 2 diabetes traditionally emphasize dietary patterns reflecting nutrient goals, but the health implications of ultra-processed food (UPF) for patients with type 2 diabetes remain unknown.ObjectiveTo evaluate the association of UPF intake with all-cause and cardiovascular disease (CVD) mortality amongst participants with type 2 diabetes from the Moli-sani… Continue reading #Ultra-processed #food consumption is associated with all-cause and #cardiovascular mortality in participants with type 2 #diabetes independent of diet quality: a prospective observational cohort study
#IQ After Pediatric #Concussion
This study investigated IQ scores in pediatric concussion (ie, mild traumatic brain injury) versus orthopedic injury.METHODS:Children (N = 866; aged 8–16.99 years) were recruited for 2 prospective cohort studies from emergency departments at children’s hospitals (2 sites in the United States and 5 in Canada) ≤48 hours after sustaining a concussion or orthopedic injury. They completed… Continue reading #IQ After Pediatric #Concussion
#Constipation Associated with #Cognitive #Aging and Decline
Key Takeaways:Chronic constipation — one bowel movement every three days or more — could signal worsening cognition.People who were chronically constipated had worse cognition equal to three years of aging, according to the study, which is the first to look at constipation’s potential impact on the aging brain.The new findings add to mounting research aligning… Continue reading #Constipation Associated with #Cognitive #Aging and Decline
#Exercise training and resting blood #pressure: a large-scale pairwise and network meta-analysis of randomised controlled trials
Objective To perform a large-scale pairwise and network meta-analysis on the effects of all relevant exercise training modes on resting blood pressure to establish optimal antihypertensive exercise prescription practices.Design Systematic review and network meta-analysis.Data sources PubMed (Medline), the Cochrane library and Web of Science were systematically searched.Eligibility criteria Randomised controlled trials published between 1990 and February 2023. All relevant… Continue reading #Exercise training and resting blood #pressure: a large-scale pairwise and network meta-analysis of randomised controlled trials
#Espresso Coffee Mitigates the Aggregation and Condensation of #Alzheimer′s Associated Tau Protein
Espresso coffee is among the most consumed beverages in the world. Recent studies report a protective activity of the coffee beverage against neurodegenerative disorders such as Alzheimer′s disease. Alzheimer′s disease belongs to a group of disorders, called tauopathies, which are characterized by the intraneuronal accumulation of the microtubule-associated protein tau in fibrillar aggregates. In this… Continue reading #Espresso Coffee Mitigates the Aggregation and Condensation of #Alzheimer′s Associated Tau Protein
Vegetarian Dietary Patterns and Cardiometabolic Risk in People With or at High Risk of Cardiovascular DiseaseA Systematic Review and Meta-analysis
MPORTANCE Plant-based diets are known to improve cardiometabolic risk in the general population, but their effects on people at high risk of cardiovascular diseases (CVDs) remain inconclusive.OBJECTIVE To assess the association of vegetarian diets with major cardiometabolic risk factors,including low-density lipoprotein cholesterol (LDL-C), hemoglobin A1c (HbA1c), systolic blood pressure (SBP), and body weight in people… Continue reading Vegetarian Dietary Patterns and Cardiometabolic Risk in People With or at High Risk of Cardiovascular DiseaseA Systematic Review and Meta-analysis
2 Medical News 