Background: Intestinal failure patients receiving home parenteral nutrition (HPN) are at high risk of dehydration and malnutrition. To optimize clinical care, accurate monitoring tools are required. This study aimed to compare the accuracy of two bioelectrical impedance analysis (BIA) devices, one that offers only BIA results and the other that offers BIA results of bioelectrical… Continue reading Comparative assessment of hydration status in intestinal failure patients receiving home parenteral nutrition using different bioimpedance analysis devices
Category: Gastroenterology
Curcumin Suppresses Growth of Recurrent Colorectal Adenoma After Endoscopic Resection: A Randomized, Double-Blind, Placebo-Controlled, Multicenter Trial
Introduction: Experimental and limited clinical studies suggest that curcumin has chemopreventive activity in the colorectum. This large-scale clinical trial evaluated the efficacy and safety of curcumin in patients with previously endoscopically resected colorectal neoplasia.Methods: This randomized, double-blind, placebo-controlled multicenter trial enrolled patients with previously resected colorectal neoplasia. Eligible patients were randomly assigned (1:1), using a… Continue reading Curcumin Suppresses Growth of Recurrent Colorectal Adenoma After Endoscopic Resection: A Randomized, Double-Blind, Placebo-Controlled, Multicenter Trial
Long-term impact of acute pancreatitis on patients’ quality of life: a multi-center prospective study in Japan
Background: Although acute pancreatitis often resolves, its long-term impact on health-related quality of life (HRQoL) and social participation remains unclear. This study investigated the longitudinal changes in HRQoL and factors affecting incomplete recovery of social participation following acute pancreatitis.Methods: This multi-center, prospective cohort study included patients aged ≥ 18 years who were hospitalized with acute… Continue reading Long-term impact of acute pancreatitis on patients’ quality of life: a multi-center prospective study in Japan
The gut microbiome in chemotherapy-induced fatigue: Exploring clinical associations and modulation via fecal microbiota transplantation in female mice
Background: Fatigue is a common and debilitating side effect of chemotherapy, negatively affecting treatment adherence and survival. Chemotherapy alters gut microbiome composition, and accumulating evidence suggests that gut microbes contribute to chemotherapy-induced fatigue. Because the gut microbiome is modifiable through targeted interventions, such as fecal microbiota transplantation (FMT), microbiome modulation has emerged as a potential… Continue reading The gut microbiome in chemotherapy-induced fatigue: Exploring clinical associations and modulation via fecal microbiota transplantation in female mice
The trajectory of inflammatory bowel disease in east and southeast Asia: transitioning from acceleration in incidence to compounding prevalence
The epidemiology of inflammatory bowel disease (IBD) progresses through four stages: emergence (stage 1), acceleration in incidence (stage 2), compounding prevalence (stage 3), and prevalence equilibrium (stage 4). Most early industrialised regions (Europe, North America, and Oceania) have reached stage 3, whereas many newly industrialised regions-those that predominantly industrialised after World War 2-are in stage… Continue reading The trajectory of inflammatory bowel disease in east and southeast Asia: transitioning from acceleration in incidence to compounding prevalence
Oral and gut microbiota features associated with weight-loss outcomes after metabolic and bariatric surgery: a pilot study
Background: Metabolic and bariatric surgery (MBS) is an effective treatment for severe obesity, yet postoperative weight loss outcomes vary considerably between patients. With the relevance of the gut microbiome for obesity, it is of interest to understand the potential role of the oral and gut microbiota for the outcome of MBS. This pilot, hypothesis-generating study… Continue reading Oral and gut microbiota features associated with weight-loss outcomes after metabolic and bariatric surgery: a pilot study
Translating artificial intelligence into clinical practice for gastrointestinal endoscopy: current applications and future perspectives
Artificial intelligence (AI) has emerged as a transformative tool in gastrointestinal (GI) endoscopy, addressing challenges in detection, diagnosis, and decision-making. In upper GI endoscopy, AI supports blind spot monitoring, Helicobacter pylori diagnosis, and the identification of premalignant and malignant lesions, with high accuracy and reduced miss rates. In lower GI endoscopy, computer-aided detection improves adenoma… Continue reading Translating artificial intelligence into clinical practice for gastrointestinal endoscopy: current applications and future perspectives
Association Between Helicobacter pylori Infection and Iron Deficiency Anemia in Adult Patients Attending a Tertiary Care Hospital
Background: Iron deficiency anemia (IDA) has been increasingly associated with Helicobacter pylori (H. pylori) infection, especially in developing countries.Objective: This study aimed to evaluate the association between H. pylori infection and IDA severity and to compare hematological parameters between H. pylori-positive and -negative adult patients attending a tertiary care hospital.Methodology: This was a cross-sectional analytical… Continue reading Association Between Helicobacter pylori Infection and Iron Deficiency Anemia in Adult Patients Attending a Tertiary Care Hospital
Colorectal cancer incidence and mortality by age group, colon location, and histology in Canada
Background: Colorectal cancer (CRC) incidence is increasing among younger individuals in many countries. We examined CRC incidence and mortality by age group, site, and histology in Canada.Methods: Data from the Canadian Cancer Registry and the Canadian Vital Statistics Death Database were used to determine CRC incidence from 1992 to 2019 and mortality from 1974 to… Continue reading Colorectal cancer incidence and mortality by age group, colon location, and histology in Canada
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