Fine Particulate Matter Air #Pollution and Mortality among Pediatric, Adolescent, and Young Adult Cancer Patients

Air pollution is a carcinogen and causes pulmonary and cardiac complications. We examined the association of fine particulate matter pollution (PM2.5) and mortality from cancer and all causes among pediatric, adolescent, and young adult (AYA) patients with cancer in Utah, a state with considerable variation in PM2.5.. ..Increases in PM2.5 per 5 μg/m3 were associated with cancer mortality in pediatric lymphomas and central nervous system … Continue reading Fine Particulate Matter Air #Pollution and Mortality among Pediatric, Adolescent, and Young Adult Cancer Patients

Multicenter initial guidance on use of antivirals for children with #COVID-19/SARS-CoV-2

Although Coronavirus Disease 2019 (COVID-19) is mild in nearly all children, a small proportion of pediatric patients develops severe or critical illness. Guidance is therefore needed regarding use of agents with potential activity against severe acute respiratory syndrome coronavirus 2 in pediatrics.. ..Given the typically mild course of pediatric COVID-19, supportive care alone is suggested for the overwhelming majority of cases. The panel suggests a … Continue reading Multicenter initial guidance on use of antivirals for children with #COVID-19/SARS-CoV-2

Antibiotic Use and Outcomes in Children in the Emergency Department With Suspected #Pneumonia

Antibiotic therapy is often prescribed for suspected community-acquired pneumonia (CAP) in children despite a lack of knowledge of causative pathogen. Our objective in this study was to investigate the association between antibiotic prescription and treatment failure in children with suspected CAP who are discharged from the hospital emergency department (ED).. ..Of 337 eligible children, 294 were matched on the basis of propensity score. There was … Continue reading Antibiotic Use and Outcomes in Children in the Emergency Department With Suspected #Pneumonia

American Academy of #Pediatrics – Section on #Surgery Five Things Physicians and Patients Should Question

. Avoid the routine use of whole-body computed #tomography (CT) scanning (pan-scanning) in pediatric trauma patients. . Avoid using computed tomography (CT scan) as the first-line imaging modality in the evaluation of suspected appendicitis in children. Ultrasound should be done first with a CT scan or magnetic resonance imaging (MRI) considered in equivocal cases. . Avoid performing antireflux operations (fundoplications) during gastrostomy insertion in most … Continue reading American Academy of #Pediatrics – Section on #Surgery Five Things Physicians and Patients Should Question

Retrospective cohort study of individuals born with low #birthweight: implications for screening practices

Previous studies have established an association between low birthweight (LBW) and future kidney disease, but few have explored the progression of kidney dysfunction through the pediatric years leading up through adolescence and young adulthood ..glomerular filtration rate (#GFR) between LBW (<2500 grams) and normal birthweight (NBW) Age at follow-up ranged 1–26 years old. GFR was found to be significantly lower in participants born with LBW … Continue reading Retrospective cohort study of individuals born with low #birthweight: implications for screening practices

Pediatric #Psychiatric Emergency Department Utilization and Fine #Particulate Matter: A Case-Crossover Study

Acute exposure to ambient particulate matter <2.5μm in aerodynamic diameter (PM2.5) has been associated with adult psychiatric exacerbations but has not been studied in children. Results:A 10-μg/m3 increase in PM2.5 was associated with a significant increase in any psychiatric ED utilization 1 [OR=1.07 (95% CI: 1.02, 1.12)] and 2 [OR=1.05 (95% CI: 1.00, 1.10)] d later. When stratified by visit reason, associations were significant for … Continue reading Pediatric #Psychiatric Emergency Department Utilization and Fine #Particulate Matter: A Case-Crossover Study