Comparison of #Acetaminophen (Paracetamol) With #Ibuprofen for Treatment of Fever or Pain in Children Younger Than 2 Years

Acetaminophen (paracetamol) and ibuprofen are the most widely prescribed and available over-the-counter medications for management of fever and pain in children. Despite the common use of these medications, treatment recommendations for young children remain divergent.. ..Overall, 19 studies (11 randomized; 8 nonrandomized) of 241 138 participants from 7 countries and various health care settings (hospital-based and community-based) were included. Compared with acetaminophen, ibuprofen resulted in reduced … Continue reading Comparison of #Acetaminophen (Paracetamol) With #Ibuprofen for Treatment of Fever or Pain in Children Younger Than 2 Years

Association Between #Epidural Analgesia During Labor and Risk of #Autism Spectrum Disorders in Offspring

Although the safety of labor epidural analgesia (LEA) for neonates has been well documented, the long-term health effects of LEA on offspring remain to be investigated… ..Among the cohort of 147 895 singleton children (74 425 boys [50.3%]; mean [SD] gestational age at delivery, 38.9 [1.5] weeks), 109 719 (74.2%) were exposed to maternal LEA. Fever during labor was observed in 13 055 mothers (11.9%) in the LEA group … Continue reading Association Between #Epidural Analgesia During Labor and Risk of #Autism Spectrum Disorders in Offspring

American Academy of Pediatrics – Section on Pediatric #Pulmonology and #Sleep Medicine

1. Avoid stepping up asthma therapy (adding new drugs or going to higher doses) before assessing adherence, appropriateness of device, and technique with current asthma medications. 2. Do not use LABA/steroid combination drugs as initial therapy for intermittent or mild persistent asthma. 3. Avoid administering nebulized medications by “blow by,” or placing the mask or nebulizer tubing near the child’s nose and mouth rather than … Continue reading American Academy of Pediatrics – Section on Pediatric #Pulmonology and #Sleep Medicine

Reducing #Antibiotic Prescribing in Primary Care for #Respiratory Illness

One-third of outpatient antibiotic prescriptions for pediatric acute respiratory tract infections (ARTIs) are inappropriate. We evaluated a distance learning program’s effectiveness for reducing outpatient antibiotic prescribing for ARTI visits.. In this stepped-wedge clinical trial run from November 2015 to June 2018, we randomly assigned 19 pediatric practices belonging to the Pediatric Research in Office Settings Network or the NorthShore University HealthSystem to 4 wedges. Visits … Continue reading Reducing #Antibiotic Prescribing in Primary Care for #Respiratory Illness

Fine Particulate Matter Air #Pollution and Mortality among Pediatric, Adolescent, and Young Adult Cancer Patients

Air pollution is a carcinogen and causes pulmonary and cardiac complications. We examined the association of fine particulate matter pollution (PM2.5) and mortality from cancer and all causes among pediatric, adolescent, and young adult (AYA) patients with cancer in Utah, a state with considerable variation in PM2.5.. ..Increases in PM2.5 per 5 μg/m3 were associated with cancer mortality in pediatric lymphomas and central nervous system … Continue reading Fine Particulate Matter Air #Pollution and Mortality among Pediatric, Adolescent, and Young Adult Cancer Patients

Multicenter initial guidance on use of antivirals for children with #COVID-19/SARS-CoV-2

Although Coronavirus Disease 2019 (COVID-19) is mild in nearly all children, a small proportion of pediatric patients develops severe or critical illness. Guidance is therefore needed regarding use of agents with potential activity against severe acute respiratory syndrome coronavirus 2 in pediatrics.. ..Given the typically mild course of pediatric COVID-19, supportive care alone is suggested for the overwhelming majority of cases. The panel suggests a … Continue reading Multicenter initial guidance on use of antivirals for children with #COVID-19/SARS-CoV-2

Antibiotic Use and Outcomes in Children in the Emergency Department With Suspected #Pneumonia

Antibiotic therapy is often prescribed for suspected community-acquired pneumonia (CAP) in children despite a lack of knowledge of causative pathogen. Our objective in this study was to investigate the association between antibiotic prescription and treatment failure in children with suspected CAP who are discharged from the hospital emergency department (ED).. ..Of 337 eligible children, 294 were matched on the basis of propensity score. There was … Continue reading Antibiotic Use and Outcomes in Children in the Emergency Department With Suspected #Pneumonia

American Academy of #Pediatrics – Section on #Surgery Five Things Physicians and Patients Should Question

. Avoid the routine use of whole-body computed #tomography (CT) scanning (pan-scanning) in pediatric trauma patients. . Avoid using computed tomography (CT scan) as the first-line imaging modality in the evaluation of suspected appendicitis in children. Ultrasound should be done first with a CT scan or magnetic resonance imaging (MRI) considered in equivocal cases. . Avoid performing antireflux operations (fundoplications) during gastrostomy insertion in most … Continue reading American Academy of #Pediatrics – Section on #Surgery Five Things Physicians and Patients Should Question

Retrospective cohort study of individuals born with low #birthweight: implications for screening practices

Previous studies have established an association between low birthweight (LBW) and future kidney disease, but few have explored the progression of kidney dysfunction through the pediatric years leading up through adolescence and young adulthood ..glomerular filtration rate (#GFR) between LBW (<2500 grams) and normal birthweight (NBW) Age at follow-up ranged 1–26 years old. GFR was found to be significantly lower in participants born with LBW … Continue reading Retrospective cohort study of individuals born with low #birthweight: implications for screening practices

Pediatric #Psychiatric Emergency Department Utilization and Fine #Particulate Matter: A Case-Crossover Study

Acute exposure to ambient particulate matter <2.5μm in aerodynamic diameter (PM2.5) has been associated with adult psychiatric exacerbations but has not been studied in children. Results:A 10-μg/m3 increase in PM2.5 was associated with a significant increase in any psychiatric ED utilization 1 [OR=1.07 (95% CI: 1.02, 1.12)] and 2 [OR=1.05 (95% CI: 1.00, 1.10)] d later. When stratified by visit reason, associations were significant for … Continue reading Pediatric #Psychiatric Emergency Department Utilization and Fine #Particulate Matter: A Case-Crossover Study