Many people listen to music for hours every day, often near bedtime. We investigated whether music listening affects sleep, focusing on a rarely explored mechanism: involuntary musical imagery (earworms). In Study 1 (N = 199, mean age = 35.9 years), individuals who frequently listen to music reported persistent nighttime earworms, which were associated with worse… Continue reading Bedtime #Music, Involuntary Musical Imagery, and #Sleep
Number of #teeth and masticatory function are associated with #sarcopenia and #diabetes mellitus status among community-dwelling older adults: A Shimane CoHRE study
We aimed to examine the number of teeth and masticatory function as oral health indices and clarify their roles in the pathogenesis of sarcopenia and diabetes mellitus in community-dwelling older adults. Subjects and methodsThis cross-sectional study was conducted with 635 older adults in Ohnan, Shimane Prefecture, in rural Japan. The number of teeth and masticatory… Continue reading Number of #teeth and masticatory function are associated with #sarcopenia and #diabetes mellitus status among community-dwelling older adults: A Shimane CoHRE study
#Calcifediol treatment and #COVID-19-related outcomes
COVID-19 is a major health problem because of saturation of intensive care units (ICU) and mortality. Vitamin D has emerged as a potential treatment able to reduce the disease severity. ObjectiveTo elucidate the effect of calcifediol [25OHD3] treatment on COVID-19-related outcomes. DesignObservational cohort study from March to May, 2020. SettingPatients admitted to COVID-19 wards of… Continue reading #Calcifediol treatment and #COVID-19-related outcomes
Consolidation of human #skill linked to waking hippocampo-neocortical replay
The introduction of rest intervals interspersed with practice strengthens wakeful consolidation of skill. The mechanisms by which the brain binds discrete action representations into consolidated, highly temporally-resolved skill sequences during waking rest are not known. To address this question, we recorded magnetoencephalography (MEG) during acquisition and rapid consolidation of a sequential motor skill. We report… Continue reading Consolidation of human #skill linked to waking hippocampo-neocortical replay
Prognostic value of #D-dimer for adverse outcomes in patients with infective #endocarditis: an observational study
Increased D-dimer levels have been shown to correlate with adverse outcomes in various clinical conditions. However, few studies with a large sample size have been performed thus far to evaluate the prognostic value of D-dimer in patients with infective endocarditis (IE). Methods613 patients with IE were included in the study and categorized into two groups… Continue reading Prognostic value of #D-dimer for adverse outcomes in patients with infective #endocarditis: an observational study
Associations Between #Fruit Intake and Risk of #Diabetes in the AusDiab Cohort
Fruit, but not fruit juice, intake is inversely associated with type 2 diabetes mellitus (T2DM). However, questions remain about the mechanisms by which fruits may confer protection. ObjectiveThe aims of this work were to examine associations between intake of fruit types and 1) measures of glucose tolerance and insulin sensitivity and 2) diabetes at follow-up.… Continue reading Associations Between #Fruit Intake and Risk of #Diabetes in the AusDiab Cohort
#Physical Activity as a Critical Component of First-Line Treatment for Elevated Blood #Pressure or #Cholesterol: Who, What, and How?: A Scientific Statement From the American Heart Association
Current guidelines published by the American Heart Association and the American College of Cardiology broadly recommend lifestyle approaches to prevent and treat elevated blood pressure and cholesterol. For patients with mildly or moderately elevated blood pressure and blood cholesterol, lifestyle-only approaches are the first line of therapy. The purpose of this scientific statement is to:… Continue reading #Physical Activity as a Critical Component of First-Line Treatment for Elevated Blood #Pressure or #Cholesterol: Who, What, and How?: A Scientific Statement From the American Heart Association
Reduced coupling between cerebrospinal fluid flow and global #brain activity is linked to #Alzheimer disease–related pathology
The glymphatic system plays an important role in clearing the amyloid-β (Aβ) and tau proteins that are closely linked to Alzheimer disease (AD) pathology. Glymphatic clearance, as well as Aβ accumulation, is highly dependent on sleep, but the sleep-dependent driving forces behind cerebrospinal fluid (CSF) movements essential to the glymphatic flux remain largely unclear. Recent… Continue reading Reduced coupling between cerebrospinal fluid flow and global #brain activity is linked to #Alzheimer disease–related pathology
A multicentre validation study of the diagnostic value of plasma #neurofilament light
Increased cerebrospinal fluid neurofilament light (NfL) is a recognized biomarker for neurodegeneration that can also be assessed in blood. Here, we investigate plasma NfL as a marker of neurodegeneration in 13 neurodegenerative disorders, Down syndrome, depression and cognitively unimpaired controls from two multicenter cohorts: King’s College London (n = 805) and the Swedish BioFINDER study (n = 1,464). Plasma… Continue reading A multicentre validation study of the diagnostic value of plasma #neurofilament light
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