Background: Evidence on the effects of 12-week telehealth-supported home-based exercise in advanced non-dialysis chronic kidney disease (CKD) remains limited. This study evaluated its effects on functional capacity, sarcopenia risk, and patient-reported outcomes in patients with stage 4-5 CKD.Methods: In this prospective, parallel-group randomized controlled trial (October 2024-July 2025), 54 non-dialysis patients aged ≥45 years with… Continue reading Effects of a telehealth-supported home-based exercise program on functional capacity, sarcopenia risk, and patient-reported outcomes in non-dialysis stage 4-5 chronic kidney disease
Tag: sarcopenia
Skeletal and cardiac muscle longitudinal associations in the Baltimore Longitudinal Study of Aging (BLSA)
Background: #Sarcopenia, the age-related loss of skeletal muscle mass and function, has been linked to adverse health outcomes. Cross-sectional associations have been observed between skeletal and cardiac muscle mass and function in healthy, community-dwelling older adults during normative aging. Further longitudinal studies on the skeletal muscle-cardiac axis during aging are needed to inform the temporal… Continue reading Skeletal and cardiac muscle longitudinal associations in the Baltimore Longitudinal Study of Aging (BLSA)
Comparison of nutrients and ultra-processed food consumption between different phenotypes defined by abdominal obesity and sarcopenia
Background: #Obesity, #sarcopenia, and sarcopenic obesity require effective nutritional strategies in public health.Methods: This cross-sectional study analyzed 535 adults aged 40–60 years in rural Korea. Participants were grouped by abdominal obesity (waist circumference ≥90 cm for men, ≥85 cm for women) and probable sarcopenia (handgrip strength ≤28 kg for men, ≤18 kg for women). Dietary intake was assessed using a… Continue reading Comparison of nutrients and ultra-processed food consumption between different phenotypes defined by abdominal obesity and sarcopenia
Impact of #frailty on balance, fall risk, and kinesiophobia in #sarcopenic elderly
Background/objective: The relationship between frailty and sarcopenia is well-known in older adults, but the factors associated with frailty were not adequately investigated. This study aimed to investigate the relationship between frailty levels and balance, fall risk, and kinesiophobia in older adults with primary sarcopenia and to compare them by sex.Methods: This cross-sectional study included 68… Continue reading Impact of #frailty on balance, fall risk, and kinesiophobia in #sarcopenic elderly
#Amino acid metabolites as potential circulating biomarkers for #sarcopenia
Sarcopenia, characterized by the loss of muscle mass and strength, is a multifactorial disorder, including metabolic disturbance. Plasma amino acids (AAs) regulate muscle protein synthesis and breakdown. This study evaluated plasma AA metabolites as potential biomarkers for sarcopenia using metabolomic analysis. We assessed 31 AA metabo lites in an age-matched discovery cohort (72 men, 36… Continue reading #Amino acid metabolites as potential circulating biomarkers for #sarcopenia
#Sarcopenia and Sarcopenic #Obesity and Mortality Among Older People
Sarcopenia and obesity are 2 global concerns associated with adverse health outcomes in older people. Evidence on the population-based prevalence of the combination of sarcopenia with obesity (sarcopenic obesity [SO]) and its association with mortality are still limited.Objective To investigate the prevalence of sarcopenia and SO and their association with all-cause mortality.Design, Setting, and Participants This large-scale,… Continue reading #Sarcopenia and Sarcopenic #Obesity and Mortality Among Older People
Socioeconomic Disadvantage is Associated with Probable Sarcopenia in Community-Dwelling Older Adults: Findings from the English Longitudinal Study of Ageing
BackgroundSarcopenia is characterized by the accelerated loss of muscle strength, mass, and function in aging. The disease is a major public health issue with emerging evidence of a disproportionate burden in areas of socioeconomic disadvantage. ObjectivesTo estimate the prevalence of probable sarcopenia overall, and according to Socioeconomic Position (SEP). To explore the association between markers… Continue reading Socioeconomic Disadvantage is Associated with Probable Sarcopenia in Community-Dwelling Older Adults: Findings from the English Longitudinal Study of Ageing
Low #muscle mass in #older adults and mortality: A systematic review and meta-analysis
Sarcopenia comprises a loss of muscle function and muscle mass. So far, the association between the later and mortality in older adults is inconsistent. A meta-analysis was performed to assess whether muscle mass measured by appendicular skeletal muscle mass index (ASMI) is associated with higher mortality in older adults. Articles of interest were searched for… Continue reading Low #muscle mass in #older adults and mortality: A systematic review and meta-analysis
Number of #teeth and masticatory function are associated with #sarcopenia and #diabetes mellitus status among community-dwelling older adults: A Shimane CoHRE study
We aimed to examine the number of teeth and masticatory function as oral health indices and clarify their roles in the pathogenesis of sarcopenia and diabetes mellitus in community-dwelling older adults. Subjects and methodsThis cross-sectional study was conducted with 635 older adults in Ohnan, Shimane Prefecture, in rural Japan. The number of teeth and masticatory… Continue reading Number of #teeth and masticatory function are associated with #sarcopenia and #diabetes mellitus status among community-dwelling older adults: A Shimane CoHRE study
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