A recent study suggested that the CHA2DS2-VASc score can risk stratify heart failure (HF) patients without atrial fibrillation (AF) for stroke. We performed a retrospective analysis using the national Veteran Affairs database to externally validate the findings. Crude incidence rates of end points were calculated. A Cox proportional model was used to study the association… Continue reading The #CHA2DS2-VASc Score for Risk Stratification of #Stroke in Heart Failure With-vs-Without Atrial #Fibrillation
Category: Cardiology
Consumption and Longitudinal Changes in #Cardiometabolic Risk Factors in the Framingham Offspring Cohort
Greater whole grain (WG) consumption is associated with reduced risk of cardiovascular disease (CVD); however, few prospective studies have examined WG or refined grain (RG) intake and intermediate cardiometabolic risk factors. ObjectivesWe examined the longitudinal association between WG and RG intake on changes in waist circumference (WC); fasting HDL cholesterol, triglyceride, and glucose concentrations; and… Continue reading Consumption and Longitudinal Changes in #Cardiometabolic Risk Factors in the Framingham Offspring Cohort
#Cardiovascular drugs and #COVID-19 clinical outcomes: A living systematic review and meta-analysis
The aim of this study was to continually evaluate the association between cardiovascular drug exposure and COVID-19 clinical outcomes (susceptibility to infection, disease severity, hospitalization, hospitalization length, and all-cause mortality) in patients at risk of/with confirmed COVID-19. MethodsEligible publications were identified from more than 500 databases on 1 November 2020. One reviewer extracted data with… Continue reading #Cardiovascular drugs and #COVID-19 clinical outcomes: A living systematic review and meta-analysis
#Social Health and #Cardiovascular Disease Risk Factors: A cross-sectional study in a healthy older adult population
Poor social health is a risk factor for cardiovascular disease (CVD), however an in-depth exploration of the link through CVD risk factors is lacking. AimTo examine the relationship between social health (social isolation, social support, loneliness) and CVD risk factors among healthy older women and men. MethodsData were from 11,498 healthy community-dwelling Australians aged ≥70… Continue reading #Social Health and #Cardiovascular Disease Risk Factors: A cross-sectional study in a healthy older adult population
Incidence of #liver-related morbidity and mortality in a population cohort of non-alcoholic fatty liver disease
Non-alcoholic fatty liver disease (NAFLD) increases morbidity and mortality. However, patients in biopsy-based cohorts are highly selected and the absolute risks of liver- and non-liver outcomes in NAFLD in population remains undefined. We analyzed both liver-related and non-liver-related outcomes in Finnish population cohorts of NAFLD. MethodsWe included 10993 individuals (6707 men, mean age 53.3±12.6 years)… Continue reading Incidence of #liver-related morbidity and mortality in a population cohort of non-alcoholic fatty liver disease
Relation of Intravascular #Volume Profiles to #Heart Failure Progression and Clinical Outcomes
Heart failure (HF) commonly progresses over time and identifying differences in volume profiles may help stratify risk and guide therapy. The aim of this study was to assess the pathophysiologic and prognostic roles of volume profiles for HF progression in stable ambulatory and hospitalized patients. HF patients who had undergone quantitative intravascular volume analysis (185… Continue reading Relation of Intravascular #Volume Profiles to #Heart Failure Progression and Clinical Outcomes
The risk of ischemic #stroke and hemorrhagic stroke in Chinese adults with low-density lipoprotein #cholesterol concentrations < 70 mg/dL
The risk of stroke in individuals with very low low-density lipoprotein cholesterol (LDL-C) concentrations remains high. We sought to prioritize predictive risk factors for stroke in Chinese participants with LDL-C concentrations < 70 mg/dL using a survival conditional inference tree, a machine learning method. MethodsThe training dataset included 9327 individuals with LDL-C concentrations < 70 mg/dL who were free… Continue reading The risk of ischemic #stroke and hemorrhagic stroke in Chinese adults with low-density lipoprotein #cholesterol concentrations < 70 mg/dL
#Homocysteine predicts vascular target organ damage in #hypertension and may serve as guidance for first-line antihypertensive therapy
Homocysteine is an independent risk factor for cardiovascular and cerebrovascular disease and has been proposed to contribute to vascular dysfunction. We sought to determine in a real-world clinical setting whether homocysteine levels were associated with hypertension mediated organ damage (HMOD) and could guide treatment choices in hypertension. We performed a cross-sectional analysis of prospectively collected… Continue reading #Homocysteine predicts vascular target organ damage in #hypertension and may serve as guidance for first-line antihypertensive therapy
Prognostic and Practical Validation of ESC/EACTS High #Ischemic Risk Definition on Long-Term Thrombotic and Bleeding Events in Contemporary #PCI Patients
The ESC/EACTS myocardial revascularization guidelines recently standardized the definition of patients at high ischemic risk (HIR). However, the ability of ESC/EACTS-HIR criteria to stratify ischemic and bleeding risk in a contemporary real-world East Asian cohort remains unexplored. Methods: A total of 10,167 consecutive patients undergoing PCI from prospective Fuwai PCI Registry (January 2013 to December… Continue reading Prognostic and Practical Validation of ESC/EACTS High #Ischemic Risk Definition on Long-Term Thrombotic and Bleeding Events in Contemporary #PCI Patients
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