#Plant‐Centered Diet and Risk of Incident #Cardiovascular Disease During Young to Middle Adulthood

The association between diets that focus on plant foods and restrict animal products and cardiovascular disease (CVD) is inconclusive. We investigated whether cumulative intake of a plant‐centered diet and shifting toward such a diet are associated with incident CVD. Methods and ResultsParticipants were 4946 adults in the CARDIA (Coronary Artery Risk Development in Young Adults)… Continue reading #Plant‐Centered Diet and Risk of Incident #Cardiovascular Disease During Young to Middle Adulthood

#NONALCOHOLIC FATTY LIVER DISEASE-RELATED RISK OF #CARDIOVASCULAR DISEASE AND OTHER CARDIAC COMPLICATIONS

Nonalcoholic fatty liver disease (NAFLD) affects approximately ~25% of the global adult population. The aim of this narrative review is to describe the associations between NAFLD and cardiovascular disease (CVD), arrhythmias, cardiac conduction defects, myocardial remodelling and heart failure. We also discuss the potential mechanisms that mediate or attenuate the strength of these associations, and… Continue reading #NONALCOHOLIC FATTY LIVER DISEASE-RELATED RISK OF #CARDIOVASCULAR DISEASE AND OTHER CARDIAC COMPLICATIONS

Extrapolating Long-term Event-Free and Overall Survival With #Dapagliflozin in Patients With #Heart Failure and Reduced #Ejection Fraction

Sodium glucose cotransporter 2 inhibitors reduce morbidity and mortality in patients with heart failure and reduced ejection fraction (HFrEF). Clinicians may find estimates of the projected long-term benefits of sodium glucose cotransporter 2 inhibitors a helpful addition to clinical trial results when communicating the benefits of this class of drug to patients. Objective To estimate… Continue reading Extrapolating Long-term Event-Free and Overall Survival With #Dapagliflozin in Patients With #Heart Failure and Reduced #Ejection Fraction

Association of #alcohol consumption with morbidity and mortality in patients with #cardiovascular disease: original data and meta-analysis of 48,423 men and women

Light-to-moderate alcohol consumption has been reported to be cardio-protective among apparently healthy individuals; however, it is unclear whether this association is also present in those with disease. To examine the association between alcohol consumption and prognosis in individuals with pre-existing cardiovascular disease (CVD), we conducted a series of meta-analyses of new findings from three large-scale… Continue reading Association of #alcohol consumption with morbidity and mortality in patients with #cardiovascular disease: original data and meta-analysis of 48,423 men and women

Evaluation of serum #calcium differences in #hypertensive crises and control patients: A randomly matched case-control study

The role of calcium in blood pressure has been widely studied among hypertensive patients; however, no study has explored the role of calcium in hypertensive crises. The primary objective of this study is to evaluate the differences in serum calcium levels between hypertensive crises patients and a 1:1 random matched controls (age-, sex-, race-, diabetes,… Continue reading Evaluation of serum #calcium differences in #hypertensive crises and control patients: A randomly matched case-control study

Association of Oral #Anticoagulation With #Stroke in Atrial #Fibrillation or Heart #Failure: A Comparative Meta-Analysis

Atrial fibrillation and heart failure with reduced ejection fraction (HFrEF) are common sources of cardioembolism. While oral anticoagulation is strongly recommended for atrial fibrillation, there are marked variations in guideline recommendations for HFrEF due to uncertainty about net clinical benefit. This systematic review and meta-analysis evaluates the comparative association of oral anticoagulation with stroke and… Continue reading Association of Oral #Anticoagulation With #Stroke in Atrial #Fibrillation or Heart #Failure: A Comparative Meta-Analysis

The #CHA2DS2-VASc Score for Risk Stratification of #Stroke in Heart Failure With-vs-Without Atrial #Fibrillation

A recent study suggested that the CHA2DS2-VASc score can risk stratify heart failure (HF) patients without atrial fibrillation (AF) for stroke. We performed a retrospective analysis using the national Veteran Affairs database to externally validate the findings. Crude incidence rates of end points were calculated. A Cox proportional model was used to study the association… Continue reading The #CHA2DS2-VASc Score for Risk Stratification of #Stroke in Heart Failure With-vs-Without Atrial #Fibrillation

Consumption and Longitudinal Changes in #Cardiometabolic Risk Factors in the Framingham Offspring Cohort

Greater whole grain (WG) consumption is associated with reduced risk of cardiovascular disease (CVD); however, few prospective studies have examined WG or refined grain (RG) intake and intermediate cardiometabolic risk factors. ObjectivesWe examined the longitudinal association between WG and RG intake on changes in waist circumference (WC); fasting HDL cholesterol, triglyceride, and glucose concentrations; and… Continue reading Consumption and Longitudinal Changes in #Cardiometabolic Risk Factors in the Framingham Offspring Cohort

#Cardiovascular drugs and #COVID-19 clinical outcomes: A living systematic review and meta-analysis

The aim of this study was to continually evaluate the association between cardiovascular drug exposure and COVID-19 clinical outcomes (susceptibility to infection, disease severity, hospitalization, hospitalization length, and all-cause mortality) in patients at risk of/with confirmed COVID-19. MethodsEligible publications were identified from more than 500 databases on 1 November 2020. One reviewer extracted data with… Continue reading #Cardiovascular drugs and #COVID-19 clinical outcomes: A living systematic review and meta-analysis