The purpose of this study was to evaluate whether the urine protein to creatinine ratio (uPCR) has have clinical significance in relation to cardiovascular risk associated with carotid artery intima-media thickness (cIMT) progression, in subjects with type 2 diabetes and normoalbuminuria. MethodsIn this retrospective longitudinal study on T2D, we recruited 927 subjects with normoalbuminuria (urine… Continue reading #Proteinuria as a Significant Predictive Factor for the Progression of Carotid Artery #Atherosclerosis in Non-Albuminuric Type 2 #Diabetes
Category: Cardiology
Effect of Long-Term Marine #Omega-3 Fatty Acids Supplementation on the Risk of Atrial #Fibrillation in Randomized Controlled Trials of Cardiovascular Outcomes: A Systematic Review and Meta-Analysis
Some, but not all, large-scale randomized controlled trials (RCTs) investigating the effects of marine omega-3 fatty acids supplementation on cardiovascular outcomes have reported increased risks of atrial fibrillation (AF). The potential reasons for disparate findings may be dose related. Methods: The MEDLINE and Embase databases were searched for articles and abstracts published between January 1,… Continue reading Effect of Long-Term Marine #Omega-3 Fatty Acids Supplementation on the Risk of Atrial #Fibrillation in Randomized Controlled Trials of Cardiovascular Outcomes: A Systematic Review and Meta-Analysis
Association of #Statin Therapy Initiation With #Diabetes ProgressionA Retrospective Matched-Cohort Study
Statin therapy has been associated with increased insulin resistance; however, its clinical implications for diabetes control among patients with diabetes is unknown. Objective To assess diabetes progression after initiation of statin use in patients with diabetes. Design, Setting, and Participants This was a retrospective matched-cohort study using new-user and active-comparator designs to assess associations between… Continue reading Association of #Statin Therapy Initiation With #Diabetes ProgressionA Retrospective Matched-Cohort Study
Long‐Term Exposure to Air #Pollution, Road #Traffic Noise, and #Heart Failure Incidence: The Danish Nurse Cohort
We examined the association of long‐term exposure to air pollution and road traffic noise with incident heart failure (HF). Methods And ResultsUsing data on female nurses from the Danish Nurse Cohort (aged >44 years), we investigated associations between 3‐year mean exposures to air pollution and road traffic noise and incident HF using Cox regression models,… Continue reading Long‐Term Exposure to Air #Pollution, Road #Traffic Noise, and #Heart Failure Incidence: The Danish Nurse Cohort
#Aging and comorbidities influence the risk of hospitalization and mortality in #diabetic patients experiencing severe hypoglycemia
Severe hypoglycemia requiring access to the Emergency Department is more frequent in older patients with multiple comorbidities.•Risk of hospitalization and mortality within one year since the hypoglycemic event is higher in older frail patients.•Severe hypoglycemia could increase the cardiovascular risk and could be a marker of future cardiovascular events.•A less stringent glycemic control and the… Continue reading #Aging and comorbidities influence the risk of hospitalization and mortality in #diabetic patients experiencing severe hypoglycemia
A Meta-Analysis on the Global Prevalence, Risk factors and Screening of Coronary #Heart Disease in Non-alcoholic #Fatty Liver Disease
Background and AimsCardiovascular disease remains the leading cause of death in patients with non-alcoholic fatty liver disease (NAFLD). Studies examining the association of coronary heart disease (CHD) and NAFLD are cofounded by various cardiometabolic factors particularly diabetes and body mass index. Hence, we seek to explore such association by investigating the global prevalence, independent risk… Continue reading A Meta-Analysis on the Global Prevalence, Risk factors and Screening of Coronary #Heart Disease in Non-alcoholic #Fatty Liver Disease
Role and Mechanism of Gut #Microbiota in Human #Disease
The human gut microbiome is a huge microbial community that plays an irreplaceable role in human life. With the further development of research, the influence of intestinal flora on human diseases has been gradually excavated. Gut microbiota (GM) dysbiosis has adverse health effects on the human body that will lead to a variety of chronic… Continue reading Role and Mechanism of Gut #Microbiota in Human #Disease
#Cysteamine Decreases Low‐Density Lipoprotein Oxidation, Causes Regression of #Atherosclerosis, and Improves #Liver and Muscle Function in Low‐Density Lipoprotein Receptor–Deficient Mice
We have shown previously that low‐density lipoprotein (LDL) can be oxidized in the lysosomes of macrophages, that this oxidation can be inhibited by cysteamine, an antioxidant that accumulates in lysosomes, and that this drug decreases atherosclerosis in LDL receptor–deficient mice fed a high‐fat diet. We have now performed a regression study with cysteamine, which is… Continue reading #Cysteamine Decreases Low‐Density Lipoprotein Oxidation, Causes Regression of #Atherosclerosis, and Improves #Liver and Muscle Function in Low‐Density Lipoprotein Receptor–Deficient Mice
The Relationship Between Body #Mass Index and In-Hospital #Mortality in the Contemporary Era of an Acute Myocardial #Infarction Management
The association between body mass index (BMI) and clinical outcomes following an acute myocardial infarction (AMI) remains controversial. Our objective was to investigate the relationship between BMI and AMI presentation, in-hospital clinical course and mortality in the contemporary era of AMI management. Methods: Patients, hospitalized for an AMI between October 2015 and December 2016, were… Continue reading The Relationship Between Body #Mass Index and In-Hospital #Mortality in the Contemporary Era of an Acute Myocardial #Infarction Management
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