Magnet wireless charging is being utilized increasingly in current generation smartphones. Apple's MagSafe is a proprietary wireless charging technology with an array of magnets that has the capacity to generate magnet fieldstrength >50 gauss (G). We hypothesize that there is clinically significant magnet interference caused by Apple's MagSafe technology on cardiac implantable electronic devices (CIED).… Continue reading Magnetic Interference on #Cardiac Implantable Electronic Devices From Apple #iPhone MagSafe Technology
Category: Cardiology
Readmission following both #cardiac and non-cardiac acute #dyspnoea is associated with a striking risk of death
Readmission and mortality are the most common and often combined endpoints in acute heart failure (AHF) trials, but an association between these two outcomes is poorly investigated. The aim of this study was to determine whether unplanned readmission is associated with a greater subsequent risk of death in patients with acute dyspnoea due to cardiac… Continue reading Readmission following both #cardiac and non-cardiac acute #dyspnoea is associated with a striking risk of death
#Zinc drives #vasorelaxation by acting in sensory nerves, endothelium and smooth muscle
Zinc, an abundant transition metal, serves as a signalling molecule in several biological systems. Zinc transporters are genetically associated with cardiovascular diseases but the function of zinc in vascular tone regulation is unknown. We found that elevating cytoplasmic zinc using ionophores relaxed rat and human isolated blood vessels and caused hyperpolarization of smooth muscle membrane.… Continue reading #Zinc drives #vasorelaxation by acting in sensory nerves, endothelium and smooth muscle
Prognostic value of #D-dimer for adverse outcomes in patients with infective #endocarditis: an observational study
Increased D-dimer levels have been shown to correlate with adverse outcomes in various clinical conditions. However, few studies with a large sample size have been performed thus far to evaluate the prognostic value of D-dimer in patients with infective endocarditis (IE). Methods613 patients with IE were included in the study and categorized into two groups… Continue reading Prognostic value of #D-dimer for adverse outcomes in patients with infective #endocarditis: an observational study
#Coronary heart disease in mothers and fathers of adult children with #alcohol use disorders
Having a family member with an alcohol use disorder (AUD) may negatively affect a person’s health. Our aim was to study the long-term risk of coronary heart disease (CHD) in parents who have an offspring with AUD. DesignCohort study. Cox regression models and co-sibling analyses. SettingSweden. ParticipantsFrom population registers, we selected all parent-offspring pairs in… Continue reading #Coronary heart disease in mothers and fathers of adult children with #alcohol use disorders
Clinical characteristics and prognosis of patients with microvascular #angina: an international and prospective cohort study by the Coronary Vasomotor Disorders International Study (COVADIS) Group
To provide multi-national, multi-ethnic data on the clinical characteristics and prognosis of patients with microvascular angina (MVA). Methods and resultsThe Coronary Vasomotor Disorders International Study Group proposed the diagnostic criteria for MVA. We prospectively evaluated the clinical characteristics of patients according to these criteria and their prognosis. The primary endpoint was the composite of major… Continue reading Clinical characteristics and prognosis of patients with microvascular #angina: an international and prospective cohort study by the Coronary Vasomotor Disorders International Study (COVADIS) Group
Evidence for a causal association between #milk intake and cardiometabolic disease outcomes using a two-sample Mendelian Randomization analysis in up to 1,904,220 individuals
High milk intake has been associated with cardio-metabolic risk. We conducted a Mendelian Randomization (MR) study to obtain evidence for the causal relationship between milk consumption and cardio-metabolic traits using the lactase persistence (LCT-13910 C > T, rs4988235) variant as an instrumental variable. MethodsWe tested the association of LCT genotype with milk consumption (for validation) and with… Continue reading Evidence for a causal association between #milk intake and cardiometabolic disease outcomes using a two-sample Mendelian Randomization analysis in up to 1,904,220 individuals
Distinctive prognostic factor of heart #failure with preserved ejection fraction stratified with admission blood pressure
The prognostic importance of admission systolic blood pressure (SBP) in heart failure with preserved ejection fraction (HFpEF) is elusive. We aimed to clarify the pathophysiological differences between patients categorized with admission SBP among HFpEF patients. Methods and resultsWe studied 1008 inpatients from PURSUIT-HFpEF, a multicentre prospective observational registry. We classified patients as having elevated (>140… Continue reading Distinctive prognostic factor of heart #failure with preserved ejection fraction stratified with admission blood pressure
#Fat-Secreted Ceramides Regulate Vascular Redox State and Influence Outcomes in Patients With #Cardiovascular Disease
Obesity is associated with increased cardiovascular risk; however, the potential role of dysregulations in the adipose tissue (AT) metabolome is unknown. ObjectivesThe aim of this study was to explore the role of dysregulation in the AT metabolome on vascular redox signaling and cardiovascular outcomes. MethodsA screen was conducted for metabolites differentially secreted by thoracic AT… Continue reading #Fat-Secreted Ceramides Regulate Vascular Redox State and Influence Outcomes in Patients With #Cardiovascular Disease
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