#Stroke risk associated with carotid and aortic #atherosclerosis in patients with atrial #fibrillation: A systematic review

This review aimed to summarize the evidence on the risk of thromboembolism associated with carotid and aortic atherosclerosis in patients with AF, and the potential impact of their inclusion in current stroke risk stratification scores. Methods MEDLINE, Web of Science and EMBASE were systematically searched to identify all published studies providing relevant data through 28 February 2021. Results We identified 10 eligible studies. There was … Continue reading #Stroke risk associated with carotid and aortic #atherosclerosis in patients with atrial #fibrillation: A systematic review

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Association of Type 2 #Diabetes Mellitus and Glycemic Control With Intracranial Plaque Characteristics in Patients With Acute Ischemic #Stroke

Type 2 diabetes mellitus (T2DM) has shown to be associated with carotid plaque vulnerability. However, the impact of T2DM on intracranial artery atherosclerosis is not well‐understood. Purpose To evaluate the association of diabetes and glycemic control with intracranial atherosclerotic plaque characteristics identified by three‐dimensional contrast enhanced MR vessel wall imaging in patients after acute ischemic stroke. Study Type Prospective. Population Two hundred and eighty‐eight symptomatic … Continue reading Association of Type 2 #Diabetes Mellitus and Glycemic Control With Intracranial Plaque Characteristics in Patients With Acute Ischemic #Stroke

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Elevated #LDL cholesterol and increased risk of myocardial #infarction and #atherosclerotic cardiovascular disease in individuals aged 70–100 years: a contemporary primary prevention cohort

Findings of historical studies suggest that elevated LDL cholesterol is not associated with increased risk of myocardial infarction and atherosclerotic cardiovascular disease in patients older than 70 years. We aimed to test this hypothesis in a contemporary population of individuals aged 70–100 years.. ..Between Nov 25, 2003, and Feb 17, 2015, 91 131 individuals were enrolled in CGPS. During mean 7·7 (SD 3·2) years of follow-up … Continue reading Elevated #LDL cholesterol and increased risk of myocardial #infarction and #atherosclerotic cardiovascular disease in individuals aged 70–100 years: a contemporary primary prevention cohort

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The change in #kidney function was associated with #carotid artery plaque in a community-based population: a cohort study

We performed the current study to evaluate the association between dynamic change in estimated glomerular filtration rate (eGFR) and the risk of carotid artery plaque (CAP) in a community-based population A total number of 37,093 Chinese adults (21,790 men and 15,303 women, aged 42.6±11.6 years) free of chronic kidney diseases were enrolled. The change in eGFR was calculated based on two measurements in 2013 and … Continue reading The change in #kidney function was associated with #carotid artery plaque in a community-based population: a cohort study

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Association of Normal Systolic Blood Pressure Level With Cardiovascular Disease in the Absence of Risk Factors

The risk of atherosclerotic cardiovascular disease (ASCVD) at currently defined normal systolic blood pressure (SBP) levels in persons without ASCVD risk factors based on current definitions is not well defined.. Of the 1457 participants, 894 were women (61.4%); mean (SD) age was 58.1 (9.8) years and mean (SD) follow-up was 14.5 (3.9) years. There was an increase in traditional ASCVD risk factors, coronary artery calcium, … Continue reading Association of Normal Systolic Blood Pressure Level With Cardiovascular Disease in the Absence of Risk Factors

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Effect of Cerebrovascular and/or Peripheral #Artery Disease With or Without Attainment of #Lipid Goals on Long-term Outcomes in Patients With Coronary Artery Disease

Involvement of atherosclerosis in extracardiac vascular territories may identify coronary artery disease (CAD) patients at higher risk for adverse events. We investigated the long-term prognostic implications of polyvascular disease in patients with CAD, and further analyzed lipid goal attainment and its relation to patient outcomes. The study was a retrospective analysis of 10,297 patients undergoing coronary revascularization, categorized as having CAD alone (83.1%) or with … Continue reading Effect of Cerebrovascular and/or Peripheral #Artery Disease With or Without Attainment of #Lipid Goals on Long-term Outcomes in Patients With Coronary Artery Disease

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Short-Term Progression of Multiterritorial Subclinical #Atherosclerosis

..Imaging detected short-term (3-year) atherosclerosis progression in 41.5% of participants (26.4% by 2DVUS, 21.3% by 3DVUS, and 11.5% by CACS), particularly in peripheral territories examined by vascular ultrasound. New atherosclerosis onset accounted for approximately one-third of total progression, also more frequently by 2DVUS and 3DVUS (29.1% and 16.6%, respectively), than by CACS (2.9%). Participants with baseline disease by all 3 modalities (n = 432) also … Continue reading Short-Term Progression of Multiterritorial Subclinical #Atherosclerosis

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Early onset of #menopause is associated with increased peripheral #atherosclerotic plaque volume and progression

Cardiovascular disease (CVD) is the leading cause of death in western countries. One risk factor unique to women is the menopausal status. The aim of this study was to analyse the influence of the onset of menopause (MP) on the extent and progression of atherosclerotic plaque volume (PV). ..110 consecutive postmenopausal women (mean age 65.5) were included. Females with an earlier onset of MP (<45 … Continue reading Early onset of #menopause is associated with increased peripheral #atherosclerotic plaque volume and progression

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