Long‐Term Exposure to Air #Pollution, Road #Traffic Noise, and #Heart Failure Incidence: The Danish Nurse Cohort

We examined the association of long‐term exposure to air pollution and road traffic noise with incident heart failure (HF). Methods And ResultsUsing data on female nurses from the Danish Nurse Cohort (aged >44 years), we investigated associations between 3‐year mean exposures to air pollution and road traffic noise and incident HF using Cox regression models, …

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Residential exposure to transportation #noise in Denmark and incidence of #dementia: national cohort study

To investigate the association between long term residential exposure to road traffic and railway noise and risk of incident dementia. Design Nationwide prospective register based cohort study. Setting Denmark. Participants 1 938 994 adults aged ≥60 years living in Denmark between 1 January 2004 and 31 December 2017. Main outcome measures Incident cases of all cause dementia …

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The Effects of Chronic Exposure to Ambient #Traffic-Related Air #Pollution on #Alzheimer’s Disease Phenotypes in Wildtype and Genetically Predisposed Male and Female Rats

Epidemiological data link traffic-related air pollution (TRAP) to increased risk of Alzheimer’s disease (AD). Preclinical data corroborating this association are largely from studies of male animals exposed acutely or subchronically to high levels of isolated fractions of TRAP. What remains unclear is whether chronic exposure to ambient TRAP modifies AD risk and the influence of …

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Early-life #environmental exposure determinants of child #behavior in Europe: A longitudinal, population-based study

BackgroundEnvironmental exposures in early life influence the development of behavioral outcomes in children, but research has not considered multiple exposures. We therefore aimed to investigate the impact of a broad spectrum of pre- and postnatal environmental exposures on child behavior. Methods and findingsWe used data from the HELIX (Human Early Life Exposome) project, which was …

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