..Our goal was to examine the association between playing games and change in cognitive function from age 11 to age 70, and from age 70 to 79.. Higher frequency of playing games was associated with higher cognitive function at age 70, controlling for age 11 cognitive function, and the majority of this association could not… Continue reading Playing analog #games is associated with reduced declines in #cognitive function: a 68 year longitudinal cohort study
#Illiteracy, #dementia risk, and cognitive trajectories among older adults with low education
..Analyses included 983 adults (≥65 years old, ≤4 years of schooling) who participated in a longitudinal community aging study. Literacy was self-reported (“Did you ever learn to read or write?”).. ..Illiterate participants were almost 3 times as likely to have dementia at baseline compared to literate participants. Among those who did not have dementia at… Continue reading #Illiteracy, #dementia risk, and cognitive trajectories among older adults with low education
Association between Dietary #Selenium Intake and the Prevalence of #Osteoporosis: A Cross-Sectional Study
To examine the correlation between dietary selenium (Se) intake and the prevalence of osteoporosis (OP) in the general middle-aged and older population in China ..Compared with the lowest quartile, the energy intake, age, gender and body mass index (BMI)-adjusted odds ratios of OP were 0.72 (95% confidence interval CI 0.55-0.94), 0.72 (95% CI 0.51-1.01) and… Continue reading Association between Dietary #Selenium Intake and the Prevalence of #Osteoporosis: A Cross-Sectional Study
#Dapagliflozin in Patients with Heart Failure and Reduced #Ejection Fraction
In patients with type 2 diabetes, inhibitors of sodium–glucose cotransporter 2 (SGLT2) reduce the risk of a first hospitalization for heart failure, possibly through glucose-independent mechanisms.. A first worsening heart failure event occurred in 237 patients (10.0%) in the dapagliflozin group and in 326 patients (13.7%) in the placebo group (hazard ratio, 0.70; 95% CI,… Continue reading #Dapagliflozin in Patients with Heart Failure and Reduced #Ejection Fraction
Altered Risk for #cardiovascular Events With Changes in the #Metabolic Syndrome Status: A Nationwide Population-Based Study of Approximately 10 Million Persons
Population-scale evidence for the association between dynamic changes in metabolic syndrome (MetS) status and alterations in the risk for major adverse cardiovascular events (MACE) is lacking ..At a median follow-up of 3.54 years, the MetS-recovery group (incidence rate, 4.55 per 1000 person-years) had a significantly lower MACE risk (adjusted IRR, 0.85 [95% CI, 0.83 to… Continue reading Altered Risk for #cardiovascular Events With Changes in the #Metabolic Syndrome Status: A Nationwide Population-Based Study of Approximately 10 Million Persons
Underuse of Clinical Decision Rules and d-#Dimer in Suspected Pulmonary #Embolism: A Nationwide Survey of the Veterans Administration Health Care System
The diagnosis of pulmonary embolism (PE) remains a challenge. CT pulmonary angiography (CTPA) for suspected PE has become the primary imaging modality, but concerns regarding overutilization, overdiagnosis, radiation, and costs have led to algorithms that combine a clinical decision rule (CDR) and highly sensitive d-dimer to identify patients in whom PE can be safely excluded… Continue reading Underuse of Clinical Decision Rules and d-#Dimer in Suspected Pulmonary #Embolism: A Nationwide Survey of the Veterans Administration Health Care System
Family history of #cancer and subsequent risk of cancer: A large‐scale population‐based prospective study in Japan
Family history (FH) of cancer is an important factor of increased risk of several cancers.. During 1,802,581 person‐years of follow‐up, a total of 16,336 newly diagnosed cancers were identified. Any site (Hazard ratios = 1.11 (95% confidence interval = 1.07–1.15]), esophagus (2.11 [1.00–4.45]), stomach (1.36 [1.19–1.55]), liver (1.69 [1.10–2.61]), pancreas (2.63 [1.45–4.79]), lung (1.51 [1.14–2.00]),… Continue reading Family history of #cancer and subsequent risk of cancer: A large‐scale population‐based prospective study in Japan
Adjunctive #Rifampin Therapy For Diabetic Foot #Osteomyelitis in the Veterans Health Administration
Among patients diagnosed with diabetes, the lifetime incidence of foot ulcers is 15%. Infection is a common complication of foot ulcers, and 20% to 60% of infections result in diabetic foot osteomyelitis (DFO). ..Patients initiating rifampin therapy within 6 weeks of the DFO diagnosis and receiving the drug for at least 14 days within 90… Continue reading Adjunctive #Rifampin Therapy For Diabetic Foot #Osteomyelitis in the Veterans Health Administration
Effects of total #sleep deprivation on procedural placekeeping: More than just lapses of attention
Total sleep deprivation (TSD) impairs attention as well as higher-order cognitive processes. Because attention is a core component of many tasks, it may fully mediate the effect of sleep deprivation on higher-order processes... A large sample of participants (N = 138 contributing data) performed the Psychomotor Vigilance Task and UNRAVEL under rested or sleep-deprived conditions.… Continue reading Effects of total #sleep deprivation on procedural placekeeping: More than just lapses of attention
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