..Thirty-day mortality was 6.0% (25 patients). Multivariate analysis revealed that infection due to A virus (P 0.035; OR 7.1; 95% CI 1.1–43.8), malnutrition (P < 0.001; OR 25.0; 95% CI 4.5–138.8), hospital-acquired infection (P 0.003; OR 12.2; 95% CI 2.3–65.1), respiratory insufficiency (PaO2/FiO2 < 300) (P < 0.001; OR 125.8; 95% CI 9.6–1648.7) and pulmonary… Continue reading Predictors of #mortality of #influenza virus infections in a Swiss Hospital during four influenza seasons: Role of quick sequential organ failure assessment
#cognitive performance in relation to #hydration status and water intake among older adults, NHANES 2011–2014
..we tested if calculated serum osmolarity (Sosm) and adequate intake (AI) of water among women (n = 1271) and men (n = 1235) ≥ 60 years old were associated with scores of immediate and delayed recall, verbal fluency, and attention/processing speed. Sosm was categorized as < 285 (hyperhydrated), 285–289, 290–294, 295–300, or > 300 (dehydrated) mmol/L. AI of water was defined as ≥ 2 L/day for women… Continue reading #cognitive performance in relation to #hydration status and water intake among older adults, NHANES 2011–2014
Complementing chronic #frailty assessment at hospital admission with an electronic frailty index (FI-Laboratory) comprising routine blood test results
..we created a frailty index from routine admission laboratory investigations (FI-Laboratory) linked to data comprising hospital outcomes. ..We found that the FI-Laboratory correlated weakly with the Clinical Frailty Scale (CFS; r2 = 0.09). An increase in the CFS and the equivalent of 3 additional abnormal laboratory test results in the FI-Laboratory, respectively, were associated with… Continue reading Complementing chronic #frailty assessment at hospital admission with an electronic frailty index (FI-Laboratory) comprising routine blood test results
Altruistic #behaviors relieve physical #pain
..Across 2 pilot studies and 3 experiments, we showed a pain-relieving effect of performing altruistic behaviors. Acting altruistically relieved not only acutely induced physical pain among healthy adults but also chronic pain among cancer patients. Using functional MRI, we found that after individuals performed altruistic actions brain activity in the dorsal anterior cingulate cortex and… Continue reading Altruistic #behaviors relieve physical #pain
Hepatic Lipoprotein Export and Remission of Human Type 2 #Diabetes after #Weight Loss
..Liver fat, VLDL1-triglyceride production, and intra-pancreatic fat decreased after weight loss and remained normalized after 24 months of remission. First-phase insulin response remained increased only in those maintaining diabetes remission. Compared with those in remission at 24 months, individuals who relapsed after initial remission had a greater rise in the content of VLDL1-triglyceride and VLDL1-palmitic… Continue reading Hepatic Lipoprotein Export and Remission of Human Type 2 #Diabetes after #Weight Loss
Association between ambient fine #particulate pollution and hospital admissions for cause specific #cardiovascular disease: time series study in 184 major Chinese cities
..At the national average level, an increase of 10 μg/m3 in PM2.5 was associated with a 0.26% (95% confidence interval 0.17% to 0.35%) increase in hospital admissions on the same day for cardiovascular disease, 0.31% (0.22% to 0.40%) for ischaemic heart disease, 0.27% (0.04% to 0.51%) for heart failure, 0.29% (0.12% to 0.46%) for heart… Continue reading Association between ambient fine #particulate pollution and hospital admissions for cause specific #cardiovascular disease: time series study in 184 major Chinese cities
State-Specific Prevalence and Characteristics of Frequent Mental Distress and History of #Depression Diagnosis Among Adults with #Arthritis— United States, 2017
..Persons with arthritis have unique challenges because the interplay between anxiety, depression, and chronic pain is cyclical, with each having the potential to exacerbate the others. What is added by this report? In 2017, frequent mental distress and history of depression were commonly reported by adults with arthritis in all states, with clustering of high… Continue reading State-Specific Prevalence and Characteristics of Frequent Mental Distress and History of #Depression Diagnosis Among Adults with #Arthritis— United States, 2017
Comparison of #Lemborexant With Placebo and #Zolpidem Tartrate Extended Release for the Treatment of Older Adults With #Insomnia Disorder
..Both doses of lemborexant therapy demonstrated statistically significant greater changes from baseline on objective sleep onset as assessed by latency to persistent sleep (log transformed) that was measured using polysomnography at the end of 1 month of treatment (nights 29 and 30) compared with placebo.. For nights 29 and 30, as measured using polysomnography, the… Continue reading Comparison of #Lemborexant With Placebo and #Zolpidem Tartrate Extended Release for the Treatment of Older Adults With #Insomnia Disorder
Risk Factors for Heart #Failure in the Community: Differences by Age and Ejection #Fraction
..the comorbidities with the largest attributable risk of heart failure were arrhythmia (48.7%), hypertension (28.4%), and coronary artery disease (33.9%); together these explained 73.0% of heart failure. Similar associations were observed for patients with reduced and preserved ejection fraction, with the exception of hypertension. The risk of heart failure attributable to hypertension was 2-fold higher… Continue reading Risk Factors for Heart #Failure in the Community: Differences by Age and Ejection #Fraction
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