Vitamin #D Insufficiency Reduces Grip Strength, Grip Endurance and Increases Frailty in Aged C57Bl/6J Mice

Low 25-OH serum vitamin D (VitD) is pervasive in older adults and linked to functional decline and progression of frailty. We have previously shown that chronic VitD insufficiency in “middle-aged” mice results in impaired anaerobic exercise capacity, decreased lean mass, and increased adiposity. Here, we examine if VitD insufficiency results in similar deficits and greater frailty progression in old-aged (24 to 28 months of age) … Continue reading Vitamin #D Insufficiency Reduces Grip Strength, Grip Endurance and Increases Frailty in Aged C57Bl/6J Mice

Rate This

#Handgrip strength variability during serial testing as an entropic biomarker of #aging: a Poincaré plot analysis

..An observational cross-sectional study was performed on 80 young adults (18–22 years old, mean age 20.01 years) and 80 older people (65–69 years old, mean age 67.13 years), with a sex ratio of 1:1 for both groups.. The analysis of the differences between groups revealed statistically significant results for most HGS-derived indices (p ≤ 0.05), and the magnitude of the differences indicated, in most situations, a large effect size (r > 0.5). Our … Continue reading #Handgrip strength variability during serial testing as an entropic biomarker of #aging: a Poincaré plot analysis

Rate This