To compare the predictive accuracy of the Suicide Intent Scale (SIS), the Suicide Assessment Scale (SUAS), the Karolinska Interpersonal Violence Scale (KIVS), and the Columbia-Suicide Severity Rating Scale (C-SSRS) for suicide attempts and suicides within 3 and 12 months of an episode of self-harm. ..At least 1 suicide attempt was recorded for 216 participants during… Continue reading A Comparison of #Suicide Risk #Scales in Predicting Repeat Suicide Attempt and Suicide: A Clinical Cohort Study
Comparisons of exacerbations and mortality among regular inhaled therapies for patients with stable chronic obstructive pulmonary disease: Systematic review and Bayesian network meta-analysis
..Compared with placebo, all drug classes significantly reduced the total exacerbations and moderate to severe exacerbations. ICS/LAMA/LABA was the most efficacious treatment for reducing the exacerbation risk (odds ratio [OR] = 0.57; 95% credible interval [CrI] 0.50–0.64; posterior probability of OR > 1 [P(OR > 1)] < 0.001). In addition, in contrast to the other… Continue reading Comparisons of exacerbations and mortality among regular inhaled therapies for patients with stable chronic obstructive pulmonary disease: Systematic review and Bayesian network meta-analysis
#Particulate matter and episodic #memory decline mediated by early neuroanatomic biomarkers of Alzheimer’s disease
Evidence suggests exposure to particulate matter with aerodynamic diameter <2.5 μm (PM2.5) may increase the risk for Alzheimer’s disease and related dementias.. ..Long-term PM2.5 exposure was associated with increased Alzheimer’s disease pattern similarity scores, which accounted for 22.6% (95% CI: 1% to 68.9%) and 10.7% (95% CI: 1.0% to 30.3%) of the total adverse PM2.5… Continue reading #Particulate matter and episodic #memory decline mediated by early neuroanatomic biomarkers of Alzheimer’s disease
Association of #troponin level and age with #mortality in 250 000 patients: cohort study across five UK acute care centres
.. A positive troponin result (that is, higher than the upper limit of normal) signified a 3.2 higher mortality hazard (95% confidence interval 3.1 to 3.2) over three years. Mortality varied noticeably with age, with a hazard ratio of 10.6 (8.5 to 13.3) in 18-29 year olds and 1.5 (1.4 to 1.6) in those older… Continue reading Association of #troponin level and age with #mortality in 250 000 patients: cohort study across five UK acute care centres
Short #Sleep Is Associated With Low Bone Mineral Density and #Osteoporosis in the Women’s Health Initiative
.. In adjusted linear regression models, women who reported sleeping 5 hours or less per night had on average 0.012 to 0.018 g/cm2 significantly lower BMD at all four sites compared with women who reported sleeping 7 hours per night (reference). In adjusted multinomial models, women reporting 5 hours or less per night had higher odds of low bone… Continue reading Short #Sleep Is Associated With Low Bone Mineral Density and #Osteoporosis in the Women’s Health Initiative
#Atopic eczema and #fracture risk in adults: A population-based cohort study
..Those with eczema had increased risk of hip (HR, 1.10; 99% CI, 1.06-1.14), pelvic (HR, 1.10; 99% CI, 1.02-1.19), spinal (HR, 1.18; 99% CI, 1.10-1.27), and wrist (HR, 1.07; 99% CI, 1.03,-1.11) fractures. We found no evidence of increased proximal humeral (HR, 1.06; 99% CI, 0.97-1.15) fracture risk. Fracture risk increased with increasing eczema severity,… Continue reading #Atopic eczema and #fracture risk in adults: A population-based cohort study
#Obesity Is the Most Common Risk Factor for Chronic #liver Disease
Obesity has been associated with liver fibrosis, yet guidelines do not emphasize it as an independent risk factor in which to have a high index of suspicion of advanced disease.. ..We prospectively recruited patients from a primary care practice with hazardous alcohol use and/or type 2 diabetes and/or obesity. Subjects were invited for a transient… Continue reading #Obesity Is the Most Common Risk Factor for Chronic #liver Disease
Relationship of #nutritional status, #inflammation, and serum #albumin levels during acute illness: A prospective study
Low serum albumin levels resulting from inflammation-induced capillary leakage or disease-related anorexia during acute illness are associated with poor outcomes. We investigated the relationship of nutritional status and inflammation with low serum albumin levels and 30-day mortality in a large cohort. ..Of 2,465 patients, 1,019 (41%) had low serum albumin levels (<34 g/L), 619 (25.1%)… Continue reading Relationship of #nutritional status, #inflammation, and serum #albumin levels during acute illness: A prospective study
Trends in Self-perceived #Weight Status, Weight Loss Attempts, and Weight Loss Strategies Among Adults in the United States, 1999-2006
..Increasing trends were observed in current measured BMI (difference, 1.20; 95% CI, 0.92-1.47; P for trend < .001), current measured weight (difference 2.77 kg; 95% CI, 1.92-3.61 kg; P for trend < .001), adjusted, self-reported, prior-year weight (difference, 2.36 kg; 95% CI, 1.52-3.21 kg; P for trend < .001), and the difference between measured and adjusted self-reported weight (difference 0.70 kg;… Continue reading Trends in Self-perceived #Weight Status, Weight Loss Attempts, and Weight Loss Strategies Among Adults in the United States, 1999-2006
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