Association of Mental Health Burden With Prenatal Cannabis Exposure From Childhood to Early AdolescenceLongitudinal Findings From the Adolescent Brain Cognitive Development (ABCD) Study

Dramatic increases in cannabis use during pregnancy are alarming because of evidence that prenatal exposure may be associated with a host of adverse outcomes. We previously found that prenatal cannabis exposure (PCE) following maternal knowledge of pregnancy is associated with increased psychopathology during middle childhood using baseline data from the Adolescent Brain Cognitive Development (ABCD) study.Here, …

Continue reading Association of Mental Health Burden With Prenatal Cannabis Exposure From Childhood to Early AdolescenceLongitudinal Findings From the Adolescent Brain Cognitive Development (ABCD) Study

Cannabis use and risks of respiratory and all-cause morbidity and mortality: a population-based, data-linkage, cohort study

Introduction Although cannabis is frequently used worldwide, its impact on respiratory health is characterised by controversy. Objective To evaluate the association between cannabis use and respiratory-related emergency room (ER) visits and hospitalisations. Methods A retrospective, population-based, cohort study was carried out, linking health survey and health administrative data for residents of Ontario, Canada, aged 12–65 …

Continue reading Cannabis use and risks of respiratory and all-cause morbidity and mortality: a population-based, data-linkage, cohort study

The associations between prenatal #cannabis use disorder and neonatal outcomes

Background and AimsCannabis use disorder (CUD) during pregnancy has increased dramatically in the United States (US). This study examined the associations between prenatal CUD and adverse neonatal outcomes and heterogeneities in the associations by mothers’ tobacco use status and race/ethnicity. DesignPopulation-based, retrospective cohort study. SettingCalifornia, USA. ParticipantsA total of 4.83 million mothers who delivered a …

Continue reading The associations between prenatal #cannabis use disorder and neonatal outcomes

Associations between adolescent #cannabis use and young-adult functioning in three longitudinal twin studies

Observational studies have linked cannabis use to an array of negative outcomes, including psychiatric symptoms, cognitive impairment, and educational and occupational underachievement. These associations are particularly strong when cannabis use occurs in adolescence. Nevertheless, causality remains unclear. The purpose of the present study was thus to examine associations between prospectively assessed adolescent cannabis use and …

Continue reading Associations between adolescent #cannabis use and young-adult functioning in three longitudinal twin studies

The effects of #alcohol and #cannabis use on the cortical thickness of #cognitive control and salience brain networks in emerging adulthood: a cotwin control study

Background Impairments in inhibitory control and its underlying brain networks (control/salience areas) are associated with substance misuse. Research often assumes a causal substance exposure effect on brain structure. This assumption remains largely untested and other factors (e.g., familial risk) may confound exposure effects. We leveraged a genetically-informative sample of 24-year-old twins and a quasi-experimental cotwin …

Continue reading The effects of #alcohol and #cannabis use on the cortical thickness of #cognitive control and salience brain networks in emerging adulthood: a cotwin control study