Dynamic Associations Between #Anxiety, #Depression, and #Tobacco Use in Older Adults: Results From The Irish Longitudinal Study on Ageing

Evidence supports moderate-to-large reductions in anxiety, depression, and perceived stress after smoking cessation; however, much of the available evidence has focused on young adults. Therefore, this study quantified associations between smoking and smoking cessation on prevalent and incident generalised anxiety disorder (GAD) and major depression (MDD) in a nationally representative sample of Irish older adults.… Continue reading Dynamic Associations Between #Anxiety, #Depression, and #Tobacco Use in Older Adults: Results From The Irish Longitudinal Study on Ageing

The associations between prenatal #cannabis use disorder and neonatal outcomes

Background and AimsCannabis use disorder (CUD) during pregnancy has increased dramatically in the United States (US). This study examined the associations between prenatal CUD and adverse neonatal outcomes and heterogeneities in the associations by mothers’ tobacco use status and race/ethnicity. DesignPopulation-based, retrospective cohort study. SettingCalifornia, USA. ParticipantsA total of 4.83 million mothers who delivered a… Continue reading The associations between prenatal #cannabis use disorder and neonatal outcomes

#Smoking is associated with impaired verbal learning and #memory performance in women more than men

Vascular contributions to cognitive impairment and dementia (VCID) include structural and functional blood vessel injuries linked to poor neurocognitive outcomes. Smoking might indirectly increase the likelihood of cognitive impairment by exacerbating vascular disease risks. Sex disparities in VCID have been reported, however, few studies have assessed the sex-specific relationships between smoking and memory performance and… Continue reading #Smoking is associated with impaired verbal learning and #memory performance in women more than men

Early-life #environmental exposure determinants of child #behavior in Europe: A longitudinal, population-based study

BackgroundEnvironmental exposures in early life influence the development of behavioral outcomes in children, but research has not considered multiple exposures. We therefore aimed to investigate the impact of a broad spectrum of pre- and postnatal environmental exposures on child behavior. Methods and findingsWe used data from the HELIX (Human Early Life Exposome) project, which was… Continue reading Early-life #environmental exposure determinants of child #behavior in Europe: A longitudinal, population-based study

#Smoking, #Radiation Therapy, and Contralateral #Breast Cancer Risk in Young Women

Evidence is mounting that cigarette smoking contributes to second primary contralateral breast cancer (CBC) risk. Whether radiation therapy (RT) interacts with smoking to modify this risk is unknown. In this multicenter, individually-matched case-control study, we examined the association between RT, smoking, and CBC risk. The study included 1,521 CBC cases and 2,212 controls with unilateral… Continue reading #Smoking, #Radiation Therapy, and Contralateral #Breast Cancer Risk in Young Women

Broadened Eligibility for #Lung #Cancer Screening Challenges and Uncertainty for Implementation and Equity

In 2013, the US Preventive Services Task Force (USPSTF) recommended annual lung cancer screening with low-dose computed tomography (CT) in US adults aged 55 to 80 years who currently smoke or formerly smoked with a 30 pack-year history, and for those who formerly smoked, quitting within the past 15 years (grade “B” recommendation).1 In this… Continue reading Broadened Eligibility for #Lung #Cancer Screening Challenges and Uncertainty for Implementation and Equity

Analysis of Active and Passive #Tobacco Exposures and Blood #Pressure in US Children and Adolescents

..Elevated blood pressure, classified as greater than 90% for a child’s age, sex, and height according to the 2017 American Academy of Pediatrics Clinical Practice Guidelines. The a priori hypothesis that there is a positive association between tobacco exposure and elevated blood pressure in the study population was tested. Analysis included logistic regression with adjustment… Continue reading Analysis of Active and Passive #Tobacco Exposures and Blood #Pressure in US Children and Adolescents

An integrative study of five biological #clocks in somatic and mental #health

Biological clocks have been developed at different molecular levels and were found to be more advanced in the presence of somatic illness and mental disorders. However, it is unclear whether different biological clocks reflect similar aging processes and determinants. In ~3000 subjects, we examined whether five biological clocks (telomere length, epigenetic, transcriptomic, proteomic, and metabolomic… Continue reading An integrative study of five biological #clocks in somatic and mental #health

#Cancer Statistics, 2021

Each year, the American Cancer Society estimates the numbers of new cancer cases and deaths in the United States and compiles the most recent data on population‐based cancer occurrence. Incidence data (through 2017) were collected by the Surveillance, Epidemiology, and End Results Program; the National Program of Cancer Registries; and the North American Association of… Continue reading #Cancer Statistics, 2021