Tag: pregnancy

The impact of timing of in utero marijuana exposure on fetal growth

On By aledopressIn Gynaecology

Objective: To examine whether timing of in utero marijuana exposure independently and negatively impacts fetal growth, and if these effects are global or specific to certain growth parameters.Study design: The two study groups were marijuana users (N = 109) and a randomly selected control group of biochemically verified non-users (n = 171). Study data were obtained via manual abstraction of electronic medical records.Results: After control for …

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Association of a Mediterranean Diet Pattern With Adverse Pregnancy Outcomes Among US Women

On By aledopressIn Diet, Gynaecology

The Mediterranean diet pattern is inversely associated with the leading causes of morbidity and mortality, including metabolic diseases and cardiovascular disease, but there are limited data on its association with adverse pregnancy outcomes (APOs) among US women.Objective  To evaluate whether concordance to a Mediterranean diet pattern around the time of conception is associated with lower risk …

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Mobile genetic elements from the maternal microbiome shape infant gut microbial assembly and metabolism

On By aledopressIn Gastroenterology, Gynaecology

The perinatal period represents a critical window for cognitive and immune system development, promoted by maternal and infant gut microbiomes and their metabolites. Here, we tracked the co-development of microbiomes and metabolomes from late pregnancy to 1 year of age using longitudinal multi-omics data from a cohort of 70 mother-infant dyads. We discovered large-scale mother-to-infant …

Continue reading Mobile genetic elements from the maternal microbiome shape infant gut microbial assembly and metabolism

Modifiable risk factors and long term risk of type 2 diabetes among individuals with a history of gestational diabetes mellitus: prospective cohort study

On By aledopressIn Diet, Endocrinology, Gynaecology

Objectives To evaluate the individual and combined associations of five modifiable risk factors with risk of type 2 diabetes among women with a history of gestational diabetes mellitus and examine whether these associations differ by obesity and genetic predisposition to type 2 diabetesSetting Nurses’ Health Study II, US.Participants 4275 women with a history of gestational diabetes mellitus, with …

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Association of Mental Health Burden With Prenatal Cannabis Exposure From Childhood to Early AdolescenceLongitudinal Findings From the Adolescent Brain Cognitive Development (ABCD) Study

On By aledopressIn Gynaecology, Psychiatry

Dramatic increases in cannabis use during pregnancy are alarming because of evidence that prenatal exposure may be associated with a host of adverse outcomes. We previously found that prenatal cannabis exposure (PCE) following maternal knowledge of pregnancy is associated with increased psychopathology during middle childhood using baseline data from the Adolescent Brain Cognitive Development (ABCD) study.Here, …

Continue reading Association of Mental Health Burden With Prenatal Cannabis Exposure From Childhood to Early AdolescenceLongitudinal Findings From the Adolescent Brain Cognitive Development (ABCD) Study